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The following excerpts are from articles or books that I have recently read. They caught my interest and I hope that you will find them worth reading. If one does spark an action on your part and you want to learn more or you choose to cite it, I urge you to actually read the article or source so that you better understand the perspective of the author(s).
Our Tiny Inner Pharmacists

[These excerpts are from an article by Claudia Wallis in the January 2020 issue of Scientific American.]

      Next time you swallow a pill, think about this: you may not be the only one digesting it. You might not even be the first. By now most people are aware that our gastrointestinal tract is teeming with microbes that live mostly in harmony with us, helping us break down food, synthesize vitamins, resist germs, and relay chemical signals to our brain and immune system. But an emerging field of research with a mouthful of a name—pharmacomicrobiomics—is demonstrating that our tiny inner denizens can process our drugs in ways that both help and harm us….

      Microbes can also sabotage the classic cardiac drug digoxin, which is used to treat arrhythmias and heart failure. Doctors have long known that about 10 percent of patients who take it do not benefit, because so much of the drug—more than 50 percent in some cases—is inactivated by a gut bacterium called Eggerthella lenta….only a few specific strains of E. lenta have this talent.

      Our inner microbes can work in our favor, too. The drug sulfasalazine, widely used for rheumatoid arthritis, Crohn’s disease and ulcerative colitis, does nothing unless gut bacteria metabolize it into an active form by breaking a chemical bond. This is also true of multiple oral antibiotics in the class known as sulfa drugs.

      Another drug that gets a microbial helping hand is metformin, the first-line medication for type 2 diabetes. In this case, it’s more of a two-way interaction. Recent studies show the drug somehow alters the mix of gut microbes in ways that make metformin more effective….

      Perhaps the most exciting work in this nascent field concerns irinotecan, used as part of a cocktail of drugs to fight advanced colon and pancreatic cancers. Irinotecan is a powerful killer of tumor cells but provokes such severe diarrhea and intestinal damage that many patients cannot tolerate enough of it to treat their disease—a phenomenon known as dose-limiting toxicity. Chemist Matthew Redinbo of the University of North Carolina at Chapel Hill has traced the issue to a family of bugs called Enterobacteriaceae (members include Salmonella and Escherichia coil). The drug, given intravenously, circulates to the tumor and gets tagged for excretion in the liver, where it is rendered harmless by the addition of a simple sugar. Unfortunately, Redinbo explains, “microbes love sugar” so when the neutralized drug hits the GI tract on its way out of the body, the bugs pick off the sugar, reactivating the toxic drug, which then proceeds to “rip the GI tract apart.”

      Motivated in part by a young colleague’s battle with colon cancer and with irinotecan's side effects, Redinbo has developed a small molecule that stops the microbes from eating the sugar so that the drug passes harmlessly through the gut….

      If Redinbo and his colleagues succeed, they will have opened the door to a class of drugs that can modify microbes with great precision….

Neighborhood Threats

[These excerpts are from an article by Melinda Wenner Moyer in the January 2020 issue of Scientific American.]

      Over the past five decades mosquito populations in parts of the U.S. have skyrocketed by a factor of 10—a situation with worrying implications for the spread of diseases such as West Nile virus, dengue and chikungunya. And some places are apparently more nerable than others. A new study…found that in Baltimore, low-income neighborhoods bear the biggest burden: they have not only more mosquitoes but also larger ones, which often survive longer. The problem most likely is rooted in the fact that Baltimore has nearly 17,000 abandoned buildings, which are concentrated in economically disadvantaged areas and serve as convenient mosquito-breeding zones. To effectively combat mosquitoes and the diseases they carry, the study suggests, cities Iwill need to account for urban infrastructure.

      …Aedes albopictus (better known as Asian tiger mosquitoes)…, introduced to the U.S. in 1987, is now the most common in many American cities. When the researchers measured the mosquitoes’ wing lengths, a proxy for body size, they found that the insects grew larger in lower-income blocks. Bigger mosquitoes are not just a bigger annoyance: the larger they are, the longer they tend to live—and the more times each one can bite. Because mosquitoes have to bite at least once to become infected with disease-causing microorganisms and again to pass them on to people, bigger mosquitoes could pose higher disease risks. Larger mosquitoes also lay more eggs, setting the stage for higher numbers later on….

      The researchers say low-income blocks produce more and larger mosquitoes because they have more abandoned buildings than affluent blocks do and are more heavily littered with discarded containers that collect standing water. And water that pools in degraded buildings is protected by shade—which helps mosquitoes grow larger. Some cities' well-intentioned efforts to plant trees in low-income blocks may worsen the problem: trees and shrubs not only shade outdoor breeding pools but also shed leaves into the water and feed the mosquito larvae, helping them grow bigger….

      Fortunately, mosquito borne diseases are not a massive problem in the U.S. for now. From January through October 2019, the Centers for Disease Control and Prevention reported 777 cases of West Nile virus and 614 cases of dengue (and most of the latter occurred in people infected outside the U.S.). But climate change could worsen the country’s disease landscape by broadening habitats and lengthening the time every summer that mosquitoes can breed and survive.

      …And low-income areas affected by natural disasters such as hurricanes can also become mosquito-breeding grounds. Research has shown that disasters disproportionately damage low-income housing, which also tends to be rebuilt slowly, if at all.

      Cities may, then, need to focus more mosquito-control efforts on these areas. Urban health departments typically educate homeowners about the importance of emptying water out of outdoor containers such as pet bowls, as well as trash and recycling bins. But nobody empties such receptacles in or around abandoned buildings, and so far most municipalities have not been willing to take on the job….

Time’s Up for “Anti-Gay Therapy”

[These excerpts are from an editorial by the editors in the January 2020 issue of Scientific American.]

      …The reason no minor should be subjected to this practice has nothing to do with partisan politics or religious beliefs. The putative therapy should be discarded because it is rooted in bad science. Its origins are tied to both rejected concepts about sexuality and therapies based on those discredited notions.

      Homosexuality—once explained erroneously as the result of an overbearing mother—was classified as a form of mental illness in psychiatry's first diagnostic manual, published in 1952. In the past, treatments to “cure” it included electroshock, chemical therapies such as the forced hormone treatments infamously inflicted on British mathematician Alan M. Turing, and the hiring of prostitutes for “behavioral” interventions. But milder versions persist today in the form of aggressive counseling and, at times, the administration of measures that induce nausea or vomiting.

      Trying to alter an individual’s sexual identity should be banned simply because of the irreparable harm it causes….

      The medical establishment, thankfully, has become a solid critic of anti-gay conversion. The American Medical Association, the American Psychological Association and other organizations characterize it as useless and injurious. The public is also opposed: a 2019 Reuters/Ipsos national poll found that 56 percent of U.S. adults think conversion therapy should be illegal.

      Although medical and psychological associations have asked explicitly that Congress and state governments ban anti-gay conversion, there has been a backlash from groups such as the Liberty Counsel, which promotes ”evangelical values….”

Asimov at 100

[These excerpts are from an article by James Gunn in the 3 January 2020 issue of Science.]

      The year 1939 was also when Asimov’s first science fiction story was published in the magazine Astounding Science Fiction. The sale of his stories paid for his college expenses, including the master's degree he would later earn in chemistry (He was rejected twice for medical school but would go on to earn his doctorate, again in chemistry.)

      In 1942, Asimov began research as a chem-ist at the Philadelphia Navy Yard. Meanwhile, he continued to sell stories but considered himself a third-rate writer until his novelette “Nightfall” received a cover story in Astounding Science Fiction in 1941. The following year, the first story of his Foundation series was published. During this period, he began the first of his robot stories, which were published together in 1950 as I, Robot….

      Kurt Vonnegut is reported to have once asked Asimov how it felt to be the man who knows everything, to which Asimov is said to have replied that he only knew how it felt /to have the reputation of omniscience….

      A case can be made that, like H. G. Wells, Asimov came along at the right time. (Wells once commented that he made his writing debut in the 1890s, when the public was looking for new writers.) But Asimov also had a restless and productive mind. His early experience of reading, and then writ-ing, science fiction gave his popular science writing a rare narrative model, while his fiction similarly benefited from his scientific training.

      Some of Asimov’s critics complained that his writing lacked style. He responded by asserting that he had a style: clarity. But it also was true that he was able to adopt new methods, particularly in his later works.

      Asimov’s fiction was based on the presumption that humanity would solve its problems by thinking coolly and logically. In his nonfiction writing, he often grappled with the messier realities of human nature. There are no records of how many minds he influenced with the latter, but his ability to communicate difficult scientific es. ideas in simple language has not been equaled since….

Study Pushes Emergence of Measles Back to Antiquity

[These excerpts are from an article by Kal Kupferschmidt in the 3 January 2020 issue of Science.]

      …Measles, which killed an estimated 142,000 people in 2017, is one of the most infectious human diseases. But when, where, and how it became a human pathogen is still debated. The closest relative of the measles virus is one that causes rinderpest, a disease that affected cattle, deer, buffalo, and other even-toed ungulate species before it was eradicated in 2011. Most researchers believe both viruses had a common ancestor that infected cattle….

      Because measles spreads so fast and infection confers lifelong immunity, scientists estimate it needs populations of 250,000 to a half-million people to avoid burning itself out. Historians believe that the largest cities reached that size around the fourth century B.C.E. But when researchers in Japan used available genomes of the measles and rinderpest viruses to build a phylogenetic tree, enabling them to date the branches, they concluded in 2010 that measles didn’t emerge until the 11th or 12th century C.E.

      The uncertainty stems in part from a surprising lack of historic sequences. Only three genomes from measles viruses occurring before 1990 are known; the oldest is one isolated in 1954 that was turned into the first measles vaccine. So Calvignac-Spencer turned to the Berlin museum, whose shelves are filled with thousands of tissues and organs floating in formalin-filled glass cases, like aquariums of human anatomy.

      Formalin fixes tissue by cross-linking proteins and other large molecules, including RNA, which the measles genome is made of. To extract RNA from such samples, scientists use techniques pioneered about 10 years ago by cancer researchers interested in formalin-fixed biopsies….

      Calvignac-Spencer’s team drew up a new phylogenetic tree using the 1912 genome as well as a new one from 1960, pieced together from a sample in another collection, and other available genomes. The resulting tree suggests the disease could have jumped to humans as early as 345 B.C.E.--- right around the time human populations reached the critical size.

      The earlier date for measles' emergence also reflects the models that the team used to analyze the viral sequences. When drawing up a family tree using differences in genomes, researchers must estimate the speed at which viral genomes diverge. In the past, their estimates were often too high, because some deleterious mutations tend to disappear over time. The new model accounts for this effect, called purifying selection. It pushes back the divergence of measles and rinderpest even without including the 1912 genome. But the genome strengthens the new timeline, Calvignac-Spencer says.

      The researchers can’t rule out that the measles virus first circulated in humans and then jumped to cattle, but that seems unlikely….And the closest relative of the two viruses, which is even older, causes peste des petits ruminants, a sheep and goat disease that probably crossed to cattle more easily than to humans….

The Higher Education Crisis

[These excerpts are from an article by Maria Ferguson in the December 2019/January 2020 issue of Phi Delta Kappan.]

      For most high school seniors (and their long-suffering parents), the holiday season is definitely not the most wonderful time of year. Soon-to-be graduates are deep in the throes of trying to figure out their next steps after graduation while their parents are busy trying to navigate costs, expectations, and lots of drama. Although not all students plan to attend college after high school, more students are pursuing a college education than ever before….almost 20 million students attended either a two- or four-year college this past fall, the highest enrollment rate ever.

      While the road to college is not easy for anyone, it can be especially challenging for low-income students. A recently released book about college admissions and the pursuit of equity in higher education sheds light on just how fundamentally inequitable thigher education can be….

      …Paul Tough…focuses on the unsavory truths about the college admissions process and how it undermines efforts to make higher education more Laccessible to low-income students….

      Tough hones in on issues many of us know well: the lingering inequities of standardized tests like the SAT and ACT; the outsized influence of the U.S. News and World Report college rankings; and the almighty algorithms that help ensure colleges and universities always meet their tuition targets. Taken together, these powerful forces form a virtually insurmountable elitist wall around higher education that calls into question the very nature of how institutions assess a student's performance and potential. We all may want to believe that U.S. education is a meritocratic endeavor, but the facts on the ground indicate otherwise. Starting with the admissions process and continuing right on through their years on campus, the inequities students of color and those who come from poverty face are formidable.

      …the College Board made a range of free test-prep resources available online after studies showed that wealthier students had a competitive edge because of the many test-prep resources their families could afford….

      …Months (years!) of discussions and negotiations have not produced any meaningful results, and the general atmosphere on the Hill is, well, not conducive to compromise….

      All of this inaction is playing out against a backdrop of mounting student debt. According to the Federal Reserve, student loan debt in the U.S. has now reached $1.6 trillion. When the words “trillion” and “debt” are used in the same sentence, one would think it is time for serious action, but the Trump administration seems to believe otherwise. Aside from a plan floated earlier this year to cap student loans (an idea most experts agree would do little to address the root causes of the debt crisis), the administration has offered no real plan to address the crisis. The one concrete step the administration did take actually works against students who are trying to avoid the curse of student debt. Earlier this year, Secretary of Education Betsy DeVos repealed the Obama-era gainful employment rule, which was developed to better protect students from predatory for-profit education providers. With its repeal, the secretary actually made it easier for profit-hungry education providers to take advantage of unwitting students.

      When looking at all these issues comprehensively, it’s hard not to believe U.S. higher education is a hot mess. But should we expect anything different when our nation’s level of income inequality is at an all-time high?...Looking ahead, it seems that if our country has indeed evolved into a knowledge-based economy, then we better get our act together when it comes to making higher education a feasible goal for most students. But righting this ship is going to take leadership, vision, and commitment, none of which seems to be present within the current administration and Congress. We have an opportunity in 2020 to bring some new ideas and energy to the problem. Let's hope U.S. voters help deliver us from this mess we are in.

Student Growth Measures: What We’ve Been Missing

[These excerpts are from an article by Doris A. Santoro in the December 2019/January 2020 issue of Phi Delta Kappan.]

      …However, NCLB [No Child Left Behind] possessed at least one major blind spot: It did little to measure students' actual academic growth. By punishing and rewarding schools on the basis of a narrow definition of proficiency — whether their students were mastering grade-level content — the law neglected other key indicators of student learning, such [as] how much progress students were making on other standards. As a result, the entire educational ecosystem, including class-room instruction, was oriented around a single and very limited measure of student performance.

      President Barack Obama’s modified version of NCLB, the Every Student Succeeds Act (ESSA), took a step to correct this problem by directing states to capture student “growth or another valid or reliable measure” as part of their accountability systems. For many, this was a positive development. In the stakeholder meetings held throughout the country to help guide the decision making for ESSA, representatives from 48 states told the Obama administration that it was important to measure growth more accurately.

      …current assessment and accountability sys-tems still fail to measure how much students actually learn….all states are still testing students and measuring instructional effectiveness on the basis of grade-level performance. As a result, these assessments measure only a slice of student learning and cannot precisely demonstrate how much or how little a student has learned. It’s like an iceberg, where only a very small amount of information is visible, while the bulk of the information remains hidden from view. Our accountability and assessment systems unfortunately measure just one tiny portion of students’ knowledge. Meanwhile, the real truth of what students are learning — or not learning —remains hidden. Because assessments and accountability focus narrowly on grade-level proficiency, teachers tend to focus their instruction only on grade-level proficiency, instead of meeting students where they are….

The Problem with Stories about Teacher “Burnout”

[These excerpts are from an article by Doris A. Santoro December 2019/January 2020 issue of Phi Delta Kappan.]

      The expressions of concern about teacher burnout correctly imply that something is amiss in many of our public schools….If teachers are burning out, it is because they are asked to do too much with insufficient support and low salaries; school resources do not come close to meeting students’ needs; and reform efforts come fast and furious, without enough time for anyone to adjust, implement, assess, and reflect.

      And yet, calling it “burnout” tells the wrong story about the kinds of pain educators are experiencing because it suggests that the problem lies within individual teachers themselves. To say they've burned out is to portray them as weak and exhausted, defeated by the pressure, with little hope for rejuvenation. Not only does this diagnosis lead policy makers to prescribe ineffectual remedies, but it likely contributes to the more significant problem I call teacher demoralization.

      …But as I use it, the term describes teachers’ feelings about the moral and ethical challenges they face. Many teachers become dissatisfied not because they’re exhausted and worn down but because they care deeply about students and the profession and they realize that school policies and conditions make it impossible for them to do what is good, right, and just.

      …If the work cannot be done ethically, then its social value and purpose are compromised, and its practitioners, such as teachers, become demoralized.

      As a teacher educator and public school advocate, I question the idea that teachers leave simply because they've burned out. The better and more accurate story is that teachers want to engage in good work that benefits students, communities, and the profession, and they become frustrated when they cannot do so. Like the story about teacher burnout, the story of teacher demoralization can be depressing because it acknowledges that many educators are unhappy with their jobs and have considered leaving the profession. But, unlike the burnout narrative, it allows for hope and possibility. To say that teachers are burned out is to imply that they are spent and done. However, to say that they are demoralized is to acknowledge that they remain passionate and energetic and would love to be given opportunities to teach in ways that are just and good….

Helping Preservice Teachers Separate Fact from Fiction

[These excerpts are from an article by Jeremy Delamarter in the December 2019/January 2020 issue of Phi Delta Kappan.]

      …Almost from the moment we are old enough to recognize the world around us, we are bombarded with images of teachers and teaching. They are in the books we read, in the childhood games of toddlers, in newspapers, and in magazines. Images of teachers “spill out into television studios, movie theaters, homes, and playgrounds, infiltrating all arenas of human activity….”

      This same hand-me-down phenomenon happens with preservice teachers. Like the rest of us, aspiring teachers have been saturated with images of teachers and classrooms.

      On one hand, these images of teaching can paint teaching in a flattering and inspiring light that can draw people into the profession. Teacher movies, for example, are essentially scripted highlight reels, showcasing three or four pivotal moments over the course of a year foregrounding relationship building and, often, racial catharsis. The teacher is the hero, the cowboy of the Wild West riding into town to save the day. No one cares for the students like this teacher does, and, consequently, his or her students’ lives are changed forever. The familiar tropes of the Hollywood teacher movie are well-worn and comfortable. Despite the fact that numerous studies have documented just how unrealistic these portrayals often are…, their appeal is undiminished, and people are often drawn to teaching in part because of these films’ implicit promises that teachers can singlehandedly change students' lives.

      On the other hand, these same images of teaching can lead to frustration and emotional turmoil, especially when new teachers enter the field and begin to face the realities of classroom practice. Our cultural images of teachers are too often one-dimensional, fictionalized accounts of a fantastically complex three-dimensional reality. In the movies, good teachers often begin the year by discarding standards-based instruction in favor of “life lessons” — there may even be a scene where the teacher literally throws the curriculum away. Imagine the fate of the new teacher who enters the classroom convinced that it’s more important to teach students to love math than it is to make sure that they can do math.

      Although changing students’ lives and fostering academic excellence are not mutually exclusive goals, the images of teaching that surround us often insist that teachers must, in fact, choose between them….

      Secondhand images of teaching are not the only shadows that get mistaken for reality, however. Even preservice teachers' own firsthand experiences as K-12 students can lead to unrealistic and incomplete expectations of teaching. Time spent in classrooms as students does not, in and of itself, prepare one for the realities of teaching. Though preservice teachers may have spent much of their lives observing their own teachers in action, the picture they have is incomplete….

      Even the most attentive K-12 student does not have access to what takes place behind the scenes. Students don't observe the meetings, trainings, and other collaborative activities that constitute much of a teacher's work. They don't see the planning, grading, or any of the other countless steps that it takes to implement effective instruction. They witness neither the self-doubt that accompanies a failed lesson nor the frustration of explaining the same thing for the third time in a row.

      …Because students don’t think like a teacher thinks, they don’t recognize the intentionality and structure behind much of what takes place in a well-run classroom. They experience it, but they don't necessarily see it for what it is.

      …Creating a thriving teacher workforce requires a willingness to guide future teachers through the sticky work of reconciling their expectations with reality. Closing the expectation gap is not supplemental to basic teacher education; it is a necessary step in the process of becoming a teacher. It is not enough for aspiring teachers to learn something new; they have to become something new, as well.

Telling New Stories about School

[These excerpts are from an article by Sarah M. Stitzlein and Kathleen Knight Abowitz in the December 2019/January 2020 issue of Phi Delta Kappan.]

      The stories we tell about schools influence our collective imagination about what schooling is and can be. They are much more than just tales we tell; they actually shape our pV beliefs and the realities that result from them….

      When we tell the story that going to school and working hard is the path to a good and lucrative job, we are promoting a set of beliefs that may lead to specific actions and outcomes, such as seeking a school that maximizes one's money-making potential. And so those stories mold the educational landscape through the policy makers we select (those who promise a strong return on our taxpayer investments in schools); the sorts of schools we offer (those aimed at preparation for well-paid careers, especially in areas high in social and economic capital); and the ways we go about assessing their quality (through tests that weed out poor-quality teachers and distinguish the best and brightest students). Our stories about education matter; they shape our preferences in the voting booth and actions on educational policies. They produce real political out-comes….

      Narratives celebrating economic aims are not new Americans have long emphasized the economic aims of education, whether those be earning certifications that lead to lucrative employment or inculcating the skills needed to succeed in a hierarchical marketplace….Since the late 19th century, business and education leaders have often been united in their expression of the idea that schools would be viewed as irrelevant and even wasteful if they could not directly link education to future job preparation and outcomes….

      Those advocating for market-based approaches tell stories with a purpose. And their stories are powerful in part because they obfuscate the interests and ideologies at play behind them. An image of happily selecting a school from an array of good choices — much as one does when selecting cereal — emphasizes the power of the consumer, but not the monetary benefit to those whose product is selected, or the harm to those who were left behind or unable to make the same choices. Policy makers…can employ such stories about school choice to increase privatization, reduce government oversight, and advance market-based reforms. Such stories have agency; they are not neutral, but rather act to bring about change, often working with the interests of school privatizers….

      …The current choice-based climate is replete with narratives that foster little reflection on public schooling's value as a public institution, its role in sustaining democracy, or its history of working to bring equal educational opportunity to more chil-dren — all of which are key aspects of the common school model and its democratic aims in early America.

      …If citizens want to shape schools with democratic purposes in mind, citizens and public education advocates need to intentionally craft new stories about present and future policy choices, resisting narratives of competition and the individualistic values driving them. Telling new stories that foreground the public or shared purposes of public education may lead us to choose candidates and back policies that better serve our children and our communities.

      …a parent who deems childrens' happiness as important may decide to support a school levy or budget to fund extracurricular activities that bring children joy, even though it is costly to taxpayers and may not deliver specific job skills….

The Toxic Twin

[These excerpts are from an article in the Winter 2020 issue of Rotunda, the member magazine of te American Museum of Natural History.]

      Our planet Earth has a twin: Venus. The second planet from the Sun and our immediate neighbor has astoundingly similar qualities to our own world. It's close in size and mass, with an internal iron core and silicate mantle and crust. Its dense atmosphere has active weather-like phenomena.

      This world also once had conditions that were very similar to those of early Earth. For 2 to 3 billion years, an active volcanic surface carved out vast plains and a mountainous landscape. Average temperatures ranged between 68 and 122 degrees Fahrenheit, and there may have even been shallow seas filled with liquid water.

      But around 700 million years ago, when multicellular life was flourishing on Earth, large amounts of carbon dioxide filled Venus' atmosphere. Today, its punishing conditions are in stark contrast with those of our own blue-and-green Earth, with its perfect setting for hosting life. Why did these two worlds diverge?

      More than 40 spacecraft have visited Venus through the years, starting with the U.S.. Mariner 2 in 1962. Currently, the Japanese mission Akatsuki is in orbit around Venus, studying atmospheric weather patterns such as the presence of lightning and looking for active signs of volcanism on the surface. But it was NASA’s Magellan mission, from 1989 to 1994, that marked a turning point in our understanding of what was then a still-“elusive” planet.

      When scientists received the first high-resolution images of the Venusian surface captured using Magellan’s Synthetic Aperture Radar “they whooped with delight at the astonishing detail captured by the spacecraft’s radar eyes,” according to The Washington Post.

      Magellan showed that Venus’ mysterious surface is complex and unique. It features thousands of volcanoes, a uniform distribution of craters formed through violent impacts of meteorites, and deep channels and wide valleys formed by ancient lava flows.

      But it’s now been 25 years since we last took a close look at Venus’ surface….

      When we do return, we’ll need to send robots in our stead. While Venus has a gravity similar to Earth's, the conditions on the ground would be deadly for human explorers. Its atmosphere is almost entirely made up of carbon dioxide, so thick that the pressure on the human body would feel like swimming 3,000 feet below the oceans’ surface. Venus, which is closer to the Sun than Earth by 26 million miles, also receives about twice as much sunlight per day.

      There’s another invisible but vital difference between Venus and Earth—a magnetic field.

      On Earth, the magnetic field created by our planet’s churning liquid iron core acts like a shield, deflecting solar wind particles. Venus, by comparison, rotates at an extremely slow rate, which is likely why it never formed a magnetic field. Without this powerful barrier against solar winds, its shallow seas dried up. With its water finally stripped away, the buildup of carbon dioxide in Venus’ atmosphere reached a point of no return, trapping solar energy as scorching heat. Temperatures soared to nearly 900 degrees Fahrenheit—hot enough to melt lead—and created thick, toxic clouds of sulfuric acid that move so furiously they circle the planet every five days….

Engineering Life

[These excerpts are from an article by Jonathan Shaw in the January/February 2020 issue of Harvard Magazine.]

      Synthetic biology, or the application of engineering principles to the design of life, presents world-changing prospects. Could components of a living cell function as tiny switches or circuits? How would that allow biomedical engineers to build biological “smart devices”—from sensors deployed inside the body to portable medical kits able to produce vaccines and antibiotics on demand? Could bacterial “factories” replace the fossil-fueled industries that produce plastics, foods, and fertilizers? Will the secrets of living creatures that enter suspended animation during periods of drought and extreme cold be harnessed to keep human victims of trauma alive? And is the genetic information preserved in long-frozen or fossilized extinct species, like woolly mammoths, sufficiently recoverable to help save living species?

      These ideas, once the stuff of science fiction, are now the stuff of science. Some aren’t yet functioning realities, but others have launched business applications, whether in medicine (such as hospital gowns that signal exposure to infection) or in land remediation (where bacterial “factories” powered by the sun capture nitrogen from the atmosphere to help plants grow). Someday, engineered forms of life that store carbon may even be one of the solutions to Earth’s climate-change problem….

      Propelling the science forward are scores of innovations in biological science, with new discoveries coming every month. Among the most important are advances in genetic editing, including improvements in accuracy, and the ability to make hundreds of changes at once. Another is computer-aided design, widely used to model biological systems, and to build new proteins by combining amino acids in ways never seen in nature. Advances in molecular engineering are driving the construction of ever-more complex circuits made from biological materials. And the ability to freeze-dry cellular transcription machinery outside the confines of cells has enabled scientists to easily manufacture proteins at will, at any time and place….

      Many of the earliest biological switches were crude and prone to accidental triggering. The inside of even a single-celled bacterium such as E. coli, where engineered synthetic circuits are often introduced and tested, is very busy….

      Agriculture is one area of critical need: a growing world population must be fed….devised a process to manufacture inexpensively one of the most energy-intensive products farmers use: fertilizer, which provides the nitrogen that plants need to grow.

      The work builds on an artificial leaf…that harnesses solar energy to split water (H2O) in order to produce hydrogen, an energy source. To create fertilizer, Silver helped connect the artificial leaf to a strain of bacteria that can “fix” both atmospheric carbon dioxide and nitrogen, converting them to organic forms that can be used by living organisms. Provided with an unlimited supply of hydrogen from the artificial leaf, the bacteria combine the hydrogen with carbon pulled from the atmosphere to create a solid fuel that the bacteria store internally, as a long-term energy supply….

      The bacteria are then mixed into the soil, where some remain, and others form associations directly with plant roots. Drawing from their stored energy reserves, they begin fixing atmospheric nitrogen, thus fertilizing the plants. (Because the carbon in the bacteria remains sequestered in the soil even after the bacteria deplete their energy stores and die, the process has the added advantage of being atmospheric carbon-negative.) On test fields, Nocera reports “big increases in crop yields” with almost no run-off, an environmentally poisonous side effect of water-soluble chemical fertilizers….

(Re)New and Improved

[These excerpts are from an article by Sarah Nightingale in the Winter 2019 issue of USC Trojan Family.]

      …Their guide on this behind-the-scenes tour, a local restaurant owner, points to what they've been looking for: a grease-splattered metal container filled with used cooking oil….

      Trying not to draw unwanted attention—they’re not there to steal anything, and questions would just slow them down—he snaps a few pictures of the grease traps. He is careful to capture the contact information for the company that promises to empty them.

      You might ask why two USC researchers care where greasy spoons dump the contents of their deep-fat fryers. The simple answer lies in the power of chemistry. They’re finding ways to transform that waste product into a much-needed renewable fuel—and make the world a cleaner place.

      …These researchers are giving a second life to byproducts and discarded materials, employing recycling and upcycling to keep waste out of landfills. Oftentimes these processes reduce the need to manufacture materials from scratch, cutting down on greenhouse gas emissions and water pollution. Ultimately, their work has a modest but increasingly important goal: to get the most out of resources with the minimum amount of waste.

      The world has a trash problem. People toss out more than 2 billion tons of garbage each year according to a World Bank report. The Environmental Protection Agency reports that the U.S. share of that pile is 262 million tons per year. Paper makes up most of it, followed by food, yard trimmings and plastic.

      The recycling of discarded plastic—which can take 1,000 years to decompose—peaked at about 9% in 2018, with the rest diverted to landfills and incinerators or simply left on the ground. That unimpressive figure nose-dived a year ago when China, long the world’s biggest importer of recyclable waste, opted out of the plastics recycling business. It feared being overwhelmed by other countries’ trash. While scientists and policymakers have contemplated creative solutions to disposing of humanity’s garbage, including launching it into space, the down-to-earth solution likely involves creating fewer single-use products and reusing the materials in the goods we do make.

      …They knew of the potential of biofuels, which burn cleaner than their petroleum-based counterparts and may reduce our dependence on foreign oil, according to the U.S. Energy Information Administration. One problem is the cost of making biofuel—an issue that has thwarted the biodiesel industry for decades. While soybeans are the biggest source of oils for the industry, the combined energy needed to grow them, extract their oils and use the oils to make biodiesel is too expensive to compete with the petroleum industry. Starting with waste cooking oil reduces the cost, but not enough to make it profitable….

      As Williams explains, the most common way to turn vegetable oil into biodiesel is a chemical reaction that produces glycerol as a byproduct. But glycerol has little use, so it’s cheap. If they’re lucky, biofuel manufacturers can sell it for a few cents per pound to livestock producers, who spray it on the ground to keep dust down. In Southeast Asia, many producers dump it into rivers….

      At USC Loker, Lu discovered a way to convert glycerol into something valuable: sodium lactate. Used in the food processing industry, the market for this non-toxic, environmentally friendly chemical is $1.5 billion and growing….

      Increasingly used by commercial air-craft manufacturers like Boeing and Airbus, carbon fiber reinforced polymer composites consist of long woven strands of carbon fibers combined with a matrix, or resin. The material’s structural marriage offers exceptional strength without substantial weight, making the composites popular for airplanes and other vehicles. Composites account for half of the weight of the world’s best-selling passenger plane, Boeing’s 787 Dreamliner, and the carbon composite chassis of BMW's popular i3 electric car is so light it can easily be lifted by two people. Compared with traditional manufacturing materials—even lightweight metals like aluminum—the weight savings offered by composites make a tangible difference in fuel efficiency.

      But there are downsides to composites: their cost, the wasteful manufacturing process and their resistance to traditional recycling….

      The process…involves cutting scraps of composite sheets into thin strips of various shapes and sizes, pressing them in molds and heating them to form new composite parts. It’s a concept he likens to the production of plywood or fiberboard.

      …While the new sheets won’t be used as major load-bearing structures in airplanes in the near future, the reclaimed composites can be crafted into structures in planes that bear less of a load, like dividers, seats and luggage compartments. They can be used for cars and buildings, too….

The Chicxulub Asteroid

[This excerpt is from chapter 9 of The Rise and Fall of the Dinosaurs, written by Steve Brusatte in 2018.]

      What happened on that day—when the Cretaceous ended with a bang and the dinosaurs' death warrant was signed—was a catastrophe of unimaginable scale that, thankfully, humankind has never experienced. A comet or an asteroid—we aren’t sure which—collided with the Earth, hitting what is now the Yucatan Peninsula of Mexico. It was about six miles…wide, or about the size of Mount Everest. It was proba-bly moving at a speed of around 67,000 miles per hour…, more than a hundred times faster than a jet airliner. When it slammed into our planet, it hit with the force of over 100 trillion tons of TNT, somewhere in the vicinity of a billion nuclear bombs’ worth of energy. It plowed some twenty-five miles…through the crust and into the mantle, leaving a crater that was over 100 miles…wide.

      The impact made an atom bomb look like a Fourth of July cherry bomb. It was a bad time to be alive.

Tyrannosaurus rex

[This excerpt is from chapter 6 of The Rise and Fall of the Dinosaurs, written by Steve Brusatte in 2018.]

      T. rex was able to gnash through most anything that it wanted to eat, whether it was splurging on a forty-foot-long Edmontosaurus or snacking on smaller contemporaries like the donkey-size ornithischian Thescelosaurus. But how did it capture its food?

      Not, as it turns out, with exceptional speed. T. rex was a special dinosaur in many ways, but one thing it could not do is move very fast. There’s a famous scene in Jurassic Park where the bloodthirsty T. rex, convulsed by its insatiable appetite for human flesh, chases down a jeep driving at highway speeds. Don’t believe the movie magic—the real T. rex likely would have been left in the dust once the jeep got up to third gear. It’s not that Rex was a plodding slouch that waddled through the forest. Far from it—T. rex was agile and energetic, and it moved with purpose, its head and tail balancing each other as it tiptoed through the trees, stalking its prey. But its maximum speed was probably in the ballpark of ten to twenty-five miles per hour. That’s faster than we can run, but it’s not as quick as a racehorse or, certainly, a car on the open road.

Explaining the Size of Sauropods

[This excerpt is from chapter 3 of The Rise and Fall of the Dinosaurs, written by Steve Brusatte in 2018.]

      Our computer modeling study and more traditional studies based on limb-bone measurements come to the same conclusion: sauropod dinosaurs were really, really big. The primitive proto-sauropods like Plateosaurus began to experiment with relatively large sizes in the Triassic, as some of them got up to about two or three tons in weight. That's roughly equivalent to a giraffe or two. But after Pangea started to split, the volcanoes erupted, and the Triassic turned into the Jurassic, the true sauropods got much larger. The ones that left tracks in the Scottish lagoon weighed about ten to twenty tons, and later in the Jurassic, famous beasties like Brontosaurus and Brachiosaurus expanded to more than thirty tons. But that was nothing compared to some supersize Cretaceous species like Dreadnoughtus, Patagotitan, Argentinosaurus—members of an aptly named subgroup called the titanosaurs—which weighed in excess of fifty tons, more than a Boeing 737.

      The biggest and heaviest land animals today are elephants. Their sizes vary, depending on where they live and which species they belong to, but most weigh about five or six tons. Apparently the largest one ever recorded was around eleven tons. They have nothing on sauropods. Which circles back to the money question: how were these dinosaurs able to attain sizes so completely out of scale with anything else evolution has ever produced?

      The first thing to consider is what animals require to become really big. Perhaps most obvious, they need to eat a lot of food. Based on their sizes and the nutritional quality of the most common Jurassic foodstuffs, it's estimated that a big sauropod like Brontosaurus probably needed to eat around a hundred pounds of leaves, stems, and twigs every day, maybe more. So they needed a way to gather and digest such vast quantities of grub. Secondly, they need to grow fast. Growing bit by bit, year by year is all well and good, but if it takes you over a century to get big, that's many opportunities for a predator to eat you, or a tree to fall on you during a storm, or a disease to take you out long before you grow into your full-size adult body. Third, they must be able to breathe very efficiently, so they can take in enough oxygen to power all of the metabolic reactions in their immense bodies. Fourth, they need to be constructed in a way that their skeleton is strong and sturdy, but also not so bulky that it can’t move. Finally, they need to shed excess body heat, because in hot weather it is very easy for a big creature to overheat and die.

      Sauropods must have been able to do all of these things. But how? Many scientists who started to ponder this riddle decades ago went for the easiest answer: maybe there was something different in the physical environment back in the Triassic, Jurassic, and Cretaceous. Perhaps gravity was weaker, so heftier animals could move and grow more easily back then. Or maybe there was more oxygen in the atmosphere, so the hulking sauropods could breathe, and therefore grow and metabolize, more efficiently. These speculations might sound convincing, but on closer scrutiny they don’t check out. There is no evidence gravity was substantially different during the Age of Dinosaurs, and oxygen levels back then were about the same as today, or maybe even slightly lower.

      That leaves only one plausible explanation: there was something intrinsic about sauropods that allowed them to break the shackles that constrained all other land animals—mammals, reptiles, amphibians, even other dinosaurs—to much smaller sizes. The key seems to be their unique body plan, which is a mixture of features that evolved piecemeal during the Triassic and earliest Jurassic, culminating in an animal perfectly adapted for thriving at large size.

      It all starts, with the neck. The long, spindly, slinky-shaped neck is probably the single most distinctive feature of sauropods. A longer-than-normal neck started to evolve in the very oldest Triassic proto-sauropods, and it got proportionally longer over time, as sauropods both added more vertebrae—the individual bones in the neck—and stretched each individual vertebra ever further. Like Iron Man’s armor, the long necks conferred a kind of superpower: they allowed sauropods to reach higher in the trees than other plant-eating animals, giving them access to a whole new source of food. They could also park themselves in one area for several hours and extend their necks up and down and all around like a cherry picker, gobbling up plants while expending very little energy. That meant they were able to eat more food, and thus take in energy more efficiently, than their competitors. That’s adaptive advantage number one: their necks permitted them to eat the huge meals necessary to put on excessive weight.

      Then there’s the way that they grew. Recall that the dinosauromorph ancestors of dinosaurs developed higher metabolisms, faster growth rates, and a more active lifestyle than many of the amphibians and reptiles that were also diversifying in the earliest Triassic. They weren't lethargic, and it didn’t take them aeons to grow into adults like an iguana or a crocodile. This was also true of all of their dinosaur descendants. Studies of bone growth indicate that most sauropods matured from guinea-pig-size hatchlings to airplane-size adults in only about thirty or forty years, an incredibly short period of time for such a remarkable metamorphosis. That’s advantage two: sauropods obtained the fast growth essential to reach large size from their distant, cat-size ancestors.

      Sauropods also retained something else from their Triassic ancestors: a highly efficient lung. The lungs of sauropods were very similar to those of birds and very different from ours. While mammals have a simple lung that breathes in oxygen and exhales carbon dioxide in a cycle, birds have what is called a unidirectional lung: air flows across it in one direction only, and oxygen is extracted during both inhalation and exhalation. The bird-style lung is extra efficient, sucking up oxygen with each breath in and each exhalation. It's an astounding feature of biological engineering, made possible by a series of balloonlike air sacs connected to the lung, which store some of the oxygen-rich air taken in during inhalation, so that it can be passed across the lung during exhalation. Don’t worry if it sounds confusing: it is such a strange lung that it took biologists many decades to figure out how it works.

      We know that sauropods had such a birdlike lung because many bones of the chest cavity have big openings, called pneumatic fenestrae, where the air sacs extended deep inside. They are exactly the same structures in modern birds, and they can only be made by air sacs. So that’s adaptation three: sauropods had ultra-efficient lungs that could take in enough oxygen to stoke their metabolism at huge size. Theropod dinosaurs had the same bird-style lungs, which could have been one factor that allowed tyrannosaurs and other giant hunters to get so large, but the ornithischian dinosaurs did not. This is why duck-billed dinosaurs, stegosaurs, horned species, and armored dinosaurs were never able to grow as huge as sauropods.

      It turns out that air sacs also have another function. Aside from storing air in the breathing cycle, they also lighten the skeleton when they invade bone. In effect, they hollow out the bone, so that it still has a strong outer shell but is much more light-weight, the way an air-filled basketball is lighter than a rock of similar size. Want to know how sauropods could hold up their long necks without toppling over like an unbalanced seesaw? It’s because all of the vertebrae were so engulfed by air sacs that they were little more than honeycombs, featherweight but still strong. And that's advantage four: the air sacs allowed sauropods to have a skeleton that was both sturdy and light enough to move around. Without air sacs, mammals, lizards, and ornithischian dinosaurs had no such luck.

      And what about the fifth special adaptation, being able to expel excess body heat? The lungs and air sacs helped with this too. There were so many air sacs, and they extended throughout so much of the body, snaking their way into bones and between internal organs, that they provided a large surface area for dissipating heat. Each hot breath would be cooled by this central air conditioning system.

      Putting it all together, that’s how you can build a supergiant dinosaur. If sauropods had lacked any one of these features—the long neck, the fast growth rates, the efficient lung, the system of skeleton-lightening and body-cooling air sacs—then they probably would not have been capable of becoming such behemoths. It wouldn’t have been biologically possible. But evolution assembled all of the pieces, put them together in the right order, and when the kit was finally assembled in the post-volcanic world of the Jurassic, sauropods suddenly found themselves able to do something no other animals, before or since, have been able to do. They became biblically huge and swept around the world; they became dominant in the most magnificent way—and they would remain so for another hundred million years.

The Size of Sauropods

[This excerpt is from chapter 3 of The Rise and Fall of the Dinosaurs, written by Steve Brusatte in 2018.]

      This raises a question that has fascinated paleontologists for over a century: how did sauropods become so large?

      It’s one of the great puzzles of paleontology. But before trying to solve it, we first need to come to grips with a more fundamental issue: how big did sauropods get? How long were they, how high could they stretch their necks, and most important, how much did they weigh? These turn out to be difficult questions to answer, particularly when it comes to weight, because you can't just stick a dinosaur on a scale and weigh it. A trade secret among paleontologists is that many of the fantastical numbers you see in books and museum exhibits—Brontosaurus weighed a hundred tons and was bigger than a plane!—are pretty much just made up. Educated guesses or, in some cases, barely that. Recently, however, paleontologists have come up with two different approaches to more accurately predict the weight of a dinosaur based on its fossil bones.

      The first is really quite simple arid relies on basic physics: heavier animals require stronger limb bones to support their weight. This logical principle is reflected in how animals are built. Scientists have measured the limb bones of many living animals, and it turns out that the thickness of the main bone in each limb that supports the animal—the femur (thighbone) for those that walk on two legs only or the femur plus the humerus (upper arm bone) for those that stand on all fours—is strongly statistically correlated with the weight of the animal. In other words, there is a basic equation that works for almost all living animals: if you can measure limb-bone thickness, you can then calculate body weight with a small but recognized margin of error—simple algebra you can do with a basic calculator.

      The second method is more intensive but a lot more interesting. Scientists are starting to build three-dimensional digital models of dinosaur skeletons, add on the skin and muscles and internal organs in animation software, and use computer programs to calculate body weight….

The End of the Triassic Period

[This excerpt is from chapter 3 of The Rise and Fall of the Dinosaurs, written by Steve Brusatte in 2018.]

      …And then, when Pangea had been stretched to its limit, the crust burst and volcanoes started to erupt, burying the basins and the creatures that lived within them.

      The first eruptions didn't occur in the Newark Basin area. They happened in what is now Morocco, which at that time was nudged up against what would become eastern North America, just a few hundred miles or so from modern New York City. Then lava began pouring out in other places where Pangea was splitting: in the Newark Basin, in what is now Brazil, in those same lake environments where we found the supersalamander graveyard in Portugal—all along that zipper line, which, many millions of years later, would transform into the Atlantic Ocean. The lava came in four waves, each scorching the once verdant rift basins, each spreading toxic fumes all over the planet, each making a bad situation worse and worse. In only about half a million years—a blink of an eye in geological terms— the eruptions stopped, but they transformed the Earth forever.

      The dinosaurs, pseudosuchian crocodile-line archosaurs, big amphibians, and early mammal relatives living in the rift basins were blissfully unaware of what was about to happen. Things went sour quickly.

      The initial eruptions in Morocco released clouds of carbon dioxide, a powerful greenhouse gas, which rapidly warmed the planet. It got so hot that strange ice formations buried within the seafloor, called clathrates, melted in unison all throughout the world’s oceans. Clathrates are unlike the solid blocks of ice we're used to, the ones we put in our drinks or carve into fancy sculptures at parties. They are a more porous substance, a latticework of frozen water molecules that can trap other substances inside it. One of those substances is methane, a gas that seeps up constantly from the deep Earth and infiltrates the oceans but is caged in the clathrates before it can leak into the atmosphere. Methane is nasty: it’s an even more powerful greenhouse gas than carbon dioxide, packing an earth-warming punch over thirty-five times as great. So when that first torrent of volcanic carbon dioxide increased global temperatures and melted the clathrates, all of that once-trapped methane was suddenly released. This initiated a runaway train of global warming. The amount of greenhouse gas in the atmosphere approximately tripled within a few tens of thousands of years, and temperatures increased by 3 or 4 degrees Celsius.

      Ecosystems on land and in the oceans couldn’t cope with such rapid change. The much hotter temperatures made it impossible for many plants to grow, and indeed upwards of 95 percent of them went extinct. Animals that fed on the plants found themselves without food, and many reptiles, amphibians, and early mammal relatives died out, like dominoes falling up the food chain. Chemical chain reactions made the ocean more acidic, decimating the shelly organisms and collapsing food webs. Climate became dangerously variable, with episodes of intense heat followed by cooler periods. This enhanced the temperature differences between northern and southern Pangea, causing the megamonsoons to become more severe, the coastal regions to become even wetter, and the continental interiors to grow much drier. Pangea had never been a particularly hospitable place, but those early dinosaurs that already were constrained by the monsoons, the deserts, and their pseudosuchian rivals were now in even worse shape.

The End of the Permian Period

[This excerpt is from chapter 1 of The Rise and Fall of the Dinosaurs, written by Steve Brusatte in 2018.]

      Imagine a continent scorched with lava. It’s the apocalyptic disaster of a bad B movie. Suffice it to say, all of the pareiasaurs, dicynodonts, and gorgonopsians living anywhere near the Siberian area code were finished. But it was worse than that. When volcanoes erupt, they don’t expel only lava, but also heat, dust, and noxious gases. Unlike lava, these can affect the entire planet. At the end of the Permian, these were the real agents of doom, and they started a cascade of destruction that would last for millions of years and irrevocably change the world in the process.

      Dust shot into the atmosphere, contaminating the high-altitude air currents and spreading around the world, blocking out the sun and preventing plants from photosynthesizing. The once lush conifer forests died out; then the pareiasaurs and dicynodonts had no plants to eat, and then the gorgonopsians had no meat. Food chains started to collapse. Some of the dust fell back through the atmosphere and combined with water droplets to form acid rain, which exacerbated the worsening situation on the ground. As more plants died, the landscape became barren and unstable, leading to massive erosion as mudslides wiped out entire tracts of rotting forest. This is why the fine mudstones in the Zachelmie quarry, a rock type indicative of calm and peaceful environments, suddenly gave way to the coarser boulder-strewn rocks so characteristic of fast-moving currents and corrosive storms. Wildfires raged across the scarred land, making it even more difficult for plants and animals to survive.

      But those were just the short-term effects, the things that happened within the days, weeks, and months after a particularly large burst of lava spilled through the Siberian fissures. The longer-term effects were even more deadly. Stifling clouds of carbon dioxide were released with the lava. As we know all too well today, carbon dioxide is a potent greenhouse gas, which absorbs radiation in the atmosphere and beams it back down to the surface, warming up the Earth. The CO2 spewed out by the Siberian eruptions didn’t raise the thermostat by just a few degrees; it caused a runaway greenhouse effect that boiled the planet. But there were other consequences as well. Although a lot of the carbon dioxide went into the atmosphere, much of it also dissolved into the ocean. This causes a chain of chemical reactions that makes the ocean water more acidic, a bad thing, particularly for those sea creatures with easily dissolvable shells. It’s why we don’t bathe in vinegar. This chain reaction also draws much of the oxygen out of the oceans, another serious problem for anything living in or around water.

      Descriptions of the doom and gloom could go on for pages, but the point is, the end of the Permian was a very bad time to be alive. It was the biggest episode of mass death in the history of our planet. Somewhere around 90 percent of all species disappeared. Paleontologists have a special term for an event like this, when huge numbers of plants and animals die out all around the world in a short time: a mass extinction. There have been five particularly severe mass extinctions over the past 500 million years. The one 66 million years ago at the end of the Cretaceous period, which wiped out the dinosaurs, is surely the most famous. We’ll get to that one later. As horrible as the end-Cretaceous extinction was, it had nothing on the one at the end of the Permian. That moment of time 252 million years ago, chronicled in the swift change from mudstone to pebbly rock in the Polish quarry, was the closest that life ever came to being completely obliterated.

      Then things got better. They always do. Life is resilient, and some species are always able to make it through even the worst catastrophes. The volcanoes erupted for a few million years, and then they stopped as the hot spot lost steam. No longer blighted by lava, dust, and carbon dioxide, ecosystems were gradually able to stabilize. Plants began to grow again, and they diversified. They provided new food for herbivores, which provided meat for carnivores. Food webs reestablished themselves. It took at least five million years for this recovery to unfold, and when it did, things were better but now very different. The previously dominant gorgonopsians, pareiasaurs, and their kin were never to stalk the lakesides of Poland or anywhere else while the plucky survivors had the whole Earth to themselves. A largely empty world, an uncolonized frontier. The Permian had transitioned into the next interval of geological time, the Triassic, and things would never be the same. Dinosaurs were about to make their entrance.

Learning to Teach

[These excerpts are from an article by Firdous A. Khan in the 20 December 2019 issue of Science.]

      While preparing to teach my first lecture as a new faculty member, I told myself: “You have many research presentations under your belt; you’ll nail this!” It didn’t take long for me to realize that I was way off base. A few minutes in, the students looked tired, distracted, and in no mood to listen—a stark contrast to my research talk audiences, which seemed attentive at least….

      I started to reflect on my own experiences as a student and tried to recall the things that helped me learn, as well as the things that didn’t. The researcher in me also began to search for scientific evidence to guide me. I sought help from experts in pedagogy, as well as colleagues who had more teaching experience than I did. They told me about tools that they used during lectures and resources on campus for new teachers.

      Within 1 year, there was a marked change in my teaching. I began to use new skills and tools that kept my students engaged. One student wrote in a teaching evaluation that my approach to teaching “made the information exciting” and “challenged students to pay attention.” Teaching gradually became a source of satisfaction rather than anxiety.

      Here are some of the lessons that have helped me become a more effective teacher.

      SEEK HELP. Teaching is a skill and as such needs to be learned. Many scientists assume that their graduate degree or post-doctoral experience qualifies them to be a teacher. The reality is far from that….

      KEEP IT INTERACTIVE. Actively engaging students is essential for holding their attention and nurturing critical thought….

      BE COMPASSIONATE. Students are more likely to learn if they feel the teacher genuinely cares about them and respects them. So treat every student with understanding and compassion, and make it clear to them that they can come to you for help. It is also important to be mindful of the diversity in student backgrounds and approaches to learning….

      Teaching isn’t always easy or intuitive, but it’s your responsibility to help your students learn. Put in the time to create an environment that maximizes learning for everyone.

A ‘Missing Link’ Microbe Emerges

[These excerpts are from an article by Elizabeth Pennisi in the 20 December 2019 issue of Science.]

      This year, microbiologists took a major step toward resolving a controversy over the origin of eukaryotes, the group that encompasses all plants and animals—including humans. After 12 years of trying, a team in Japan succeeded in growing a mysterious microbe from deep-sea sediments and sequenced its genome. It could shed light on the ultimate ancestry of us all.

      The organism, Prometheoarchaeum syntrophicum strain MK-D1, is a member of the recently recognized Asgard group of microbes, which are not bacteria but a completely separate branch of life called archaea. The Asgards were known only from DNA fragments isolated from deep-sea sediments and other extreme environments. Surprisingly, those fragments contain genes formerly thought to be found only in eukaryotes—organisms with cells that have nuclei and organelles such as mitochondria. Comparative DNA analyses indicated the Asgards, or an ancient relative, may have even given rise to eukaryotes. That radical idea would shrink the domains of life from three—archaea, eukaryotes, and bacteria—to two: bacteria and archaea, with eukaryotes reduced to a subset of archaea. But given the scant evidence, many researchers were skeptical.

      By growing an Asgard in culture, the team in Japan could sequence its full genome and confirm that it carries eukaryotic genes. The researchers also found that it seems to grow best in association with certain bacteria, and that it forms short tentacles that might engulf bacterial companions. If so, that could explain how an Asgard acquired the microbial guests that became mitochondria….

      Other studies this year have identified more eukaryotic genes in DNA fragments from other members of the Asgard group. And information derived from DNA about Asgard metabolism also bolsters the two-domain over the three-domain hypothesis. Proponents of both ideas agree, however, that events that happened almost 3 billion years ago will be hard to reconstruct, and that new ideas may emerge as more Asgards are studied—and, perhaps, cultured. But with one now in hand, researchers have a clearer window into that distant past.

Face to Face with the Denisovans

[This article by Elizabeth Culotta is in the 20 December 2019 issue of Science.]

      Almost 40 years ago, a Buddhist monk found an odd human jaw bone in Baishiya Karst Cave, high on the edge of the Tibetan Plateau. Recognizing that the jaw, with its giant molars, was something special, he gave it to another monk, who donated it to scholars. But no one knew what to make of it. Then in May, scientists applied a new method of analyzing ancient proteins and identified the strange jaw as that of a Denisovan, a mysterious human ancestor who ranged across Asia until some 50,000 years ago, about the same time as the Neanderthals. The work brings these enigmatic ancient people into focus, and heralds a potential protein-based revolution in understanding ancient life.

      The Denisovans have haunted human evolution researchers for 10 years. Back in 2010, researchers identified them by sequencing DNA from a fossilized pinkie bone found in Denisova Cave in Siberia. The DNA, which came from a girl, differed from that of Neanderthals and modern humans. Today, ghostly traces of Denisovans linger in the DNA of living people across Asia, suggesting the group was once widespread and mingled with both Neanderthals and modern humans. But until this year, only a few scraps of additional Denisovan fossils had been identified, all from Denisova Cave. Scientists were left guessing what the Denisovans looked like.

      The 160,000-year-old Baishiya jaw yielded no DNA. But a Chinese and European team managed to extract collagen, a common protein, from the bone, and match it with collagen from the Denisova Cave girl. That suggested the jaw was Denisovan and that these mystery humans had robust jaws, big molars, and teeth with three roots.

      In September, another team refined that picture by applying a new technique to the Denisova Cave girl’s genome. They traced chemical modifications of the DNA called methylation, which can silence genes, then combined that information with a data-base that describes how missing or defective genes influence anatomy in living people. The results suggested how the methylation pattern of the girl's DNA might have shaped her body. The team concluded that she would have looked a lot like a Neander-thal, with a wide pelvis, sloping forehead, and protruding lower jaw. But she also had a wider face than modern humans or Neanderthals, and a longer arch of teeth along her jaw bone. When the researchers tested their view of the Denisovan smile against the newly identified Baishiya jaw bone, it fit almost perfectly.

The Rhetorical Secretary

[These excerpts are from an article by Mark Hlavacik in the December 2019/January 2020 issue of Phi Delta Kappan.]

      …Founded in 1979, the Department of Education was meant to institutionalize the government’s role in leading civic discussion about education. As he signed the legislation creating the new federal agency, Jimmy Carter explained that he considered its rhetorical mission the equal of its regulatory mission:

        I came to the office of the Presidency determined that the American people should receive a better return on their investment in education. I came equally determined that our Nation’s formidable educational challenges should be brought to the forefront of national discussion where they belong.

      For Carter, the secretary of education would be integral to the success of the new department because the secretary would be the driving force behind its rhetorical leadership. “For the first time,” he declared, “there will be a Cabinet-level leader in education, someone with the status and the resources to stir national discussion of critical educational concerns.” By “stimulating needed debate of educational issues,” the secretary was to be, in effect, a national storyteller for the schools.

      Forty years later, it is safe to say that Carter’s vision has been fulfilled. The secretaries of education — 13 of them to date — have been integral to every major civic discussion of education from the 1980s to the present. Indeed, it has become difficult to imagine what a national discussion of education policy would sound like without their leadership.

      And yet, that is exactly what Secretary Betsy DeVos has challenged us to do. Portraying the very existence of the Department of Education as a “giant nod to union bosses,” DeVos counts its creation among a series of failed reforms. To correct this misstep, she urges her fellow Americans to cut government out of the loop, insisting that “federal mandates distort what education ought to be: a trusting relationship between teacher, parent, and student.”

      …Just as Carter hoped, education has become a national political issue, featuring arguments over accountability, choice, and equity that rely on comparisons between schools that are most meaningful when made at scale….So, although Carter declared the regulatory and rhetorical functions of the Department of Education equal, the reality is that most secretaries of education have relied on the bully pulpit as their main source of influence….

      Whenever the secretary points to a specific student, teacher, administrator, school, district, or state, and whenever she releases a report or changes a policy, the content of the story she tells is met with scrutiny, discussion, and further research, as it should be. In this way, secretaries of education are held accountable by journalists, academics, teachers, and the public for the veracity, consistency, and fairness of what they say….

      However, among those who’ve had the most lasting impact on the politics of education, we can make one generalization: While they've differed widely in their policy preferences, they’ve shared a basic commitment to encouraging the American people to take collective responsibility for the nation’s educational future….

Planning for a Warmer World

[These excerpts are from an article by Daniel A. Reifsnyder in the 13 December 2019 issue of Science.]

      …the authors point to “no more” moments that can bring about large-scale, decisive action, but they acknowledge that “the rest of the time we largely fail to learn from our experience.” Take, for example, their stunning observation that 8 of the 18 most hurricane-prone states in the union have no mandatory, statewide building code.

      Why does this happen? In their view, the reasons are many and include prohibitive construction costs, the potential for lost tax revenue, a fear of litigation, optimism bias (our tendency to believe that situations will resolve favorably), and inertia.

      …human biases that I make us reluctant to act. Here, they describe the staggering costs borne by the federal government for disaster relief ($130 billion between 2005 and 2008, for example, spent mostly in response to Hurricanes Katrina, Rita, and Wilma). The authors cite former l'reasury Secretary Henry Paulson’s argument that if Republicans really care about limited government, they should care about controlling climate change before it results in never-ending climate bailouts.

      …For years, the issue of displacement and relocation was something of a taboo subject in international climate debates, both because it is so sensitive and because solutions are not readily apparent….

      …even the Obama White House dropped “managed retreat” for more politically palatable alternatives. “Our political leaders will need to begin a national conversation on this sensitive topic, and the sooner the better….The earlier we start, the easier, and less costly, and less traumatic building resilience will be….”

DNA from Arctic Lakes Traces Past Climate Impacts

[These excerpts are from an article by Paul Voosen in the 13 December 2019 issue of Science.]

      High in the Canadian Arctic on Baffin Island, beneath 10 meters of water and many more of mud, sits a refrigerated archive of Earth’s past life. The deep sediments in a small lake called CF8 hold ancient pollen and plant fossils. But it now appears that the mud harbors something else: ancient DNA from as far back as the Eemian, a period 125,000 years ago when the Arctic was warmer than today, left by vegetation that otherwise would have vanished without a trace….

      Lately, Arctic lakes have emerged as the premier archive for sedimentary ancient DNA, because they collect clues to entire ecosystems. Leaves, flowers, dung—some part of every organism that lives around a lake ends up in the water….DNA is sprung from its cells by decay, then attaches to mineral grains or organic compounds, which provide protection from ultraviolet radiation and oxidation. Temperatures at the lake bottom hover just above freezing, keeping the DNA stable. And year after year, the sediment keeps accumulating, its layers allowing clear dating of the DNA’s deposition.

      Traditionally scientists have used pollen grains from lakebed cores to study past plant communities. But most plants in the Arctic are pollinated by insects, not by wind, so that little pollen ends up in the soil—and what’s there could have blown in from a distance. DNA in lake sediments more accurately reflects the plants and wildlife found nearby….

      It’s not easy to extract the DNA. Scientists must be careful to collect a sample—typically 1 gram of mud—without contaminating it with modern DNA. Then, in a clean lab, the DNA must be extracted in a painstaking process of trial and error….Organic-rich soils seem to be particularly problematic; they are ripe with molecules like humic acid, which behaves like DNA and can foul later 14equencing efforts….

      Early results challenge the simple notion that climate change triggers a wholesale turnover of plant species….certain larch species did not shift northward as the planet warmed after the last ice age, despite preferring a colder climate. Instead …warming allowed the forest to grow denser, which favored a cold-loving larch….The DNA suggests taller plants invaded as the region warmed: first shrubs, then trees. But Arctic flowers persisted, perhaps by retreating uphill.

      Future climate warming, however, may dislodge—or extirpate—these holdouts. For clues to the fate of ecosystems in an even warmer world, researchers want to find other ancient DNA records that stretch back to the Eemian….

      And as the lakes yield even older records, the field is inching toward studying not only the changes in plant diversity and abundance, but also how individual species adapted to climate change….

Donkeys Face Worldwide Existential Threat

[These excerpts are from an article by Crista Leste-Lasserre in the 13 December 2019 issue of Science.]

      …Over the past 6 years, Chinese traders have been buying the hides of millions of butchered donkeys (Equus asinus) from develop-ing countries and shipping them to China, where they’re used to manufacture ejiao, a traditional Chinese medicine. The trade has led to an animal welfare nightmare, along with a threat to donkey populations, the severity of which is only now emerging. Without drastic measures, the number of donkeys worldwide will drop by half within 5 years….The crisis threatens many of the world's rarer donkey breeds and a vital means of transport for the poor. But it is also spurring new studies of donkey biology—including how to speed their reproduction.

      Ejiao, in use for thousands of years, purportedly treats or prevents many problems, including miscarriage, circulatory issues, and premature aging, although no rigorous clinical trials support those claims. The preparation combines mineral-rich water from China’s Shandong province and collagen extracted from donkey hides, traditionally produced by boiling the skins in a 99-step process. Once reserved for China’s elites, ejiao is now marketed to the country’s booming middle class, causing demand to surge….

      Despite government incentives for new donkey farmers, farms in China can’t keep up with the exploding demand, which the Donkey Sanctuary currently estimates at 4.8 million hides per year. Donkeys’ gestation period is one full year, and they only reach their adult size after 2 years. So the industry has embarked on a frenzied hunt for donkeys elsewhere. This has triggered steep population declines. In Brazil, the population dropped by 28% between 2007 and 2017, according to the new report….

What’s the Deal with Rich Men and Space?

[These excerpts are from an article by Zeynep Tufekci in the December 2019 issue of Scientific American.]

      …what’s wrong with dreaming, right? In one sense, nothing. But in another, it matters how people with a lot of money dream. Bezos, Allen and Musk all have talked about their love of science fiction as part of their inspiration for investing in space. Bezos spent his summers reading authors such as Isaac Asimov and Robert A. Heinlein….

      As a former science-fiction geek myself, I can only sympathize. At its best, though, science fiction is a brilliant vehicle for exploring not the far future or the scientifically implausible but the interactions among science, technology and society. The what-if scenarios it poses can allow us to understand our own societies better, and sometimes that's best done by dispensing with scientific plausibility. For example, Ursula K. Le Guin’s brilliant book The Left Hand of Darkness imagines an envoy from Terra (our Earth) to Gethen, a planet without fixed boundaries between genders. Through the hero's encounter with an “ambisexual” species, we end up interrogating our own cultural norms around masculinity and femininity—groundbreaking for a book published in 1969.

      Science fiction is sometimes denigrated as escapist literature, but the best examples of it are exactly the opposite. For me, it’s not the scientifically implausible part of science fiction that is most interesting. It's what the expanded imagination allows us to discover about ourselves and our societies—and then to make them better.

      Science and art have always been somewhat funded through the eccentric interests of the wealthy, and the combination has always been a mixed bag. One thing about being a billionaire is that it’s probably not hard to find people who will encourage you to spend money chasing space operas that either will not happen because of scientific constraints or will end up in disaster.

      But more important, tech billionaires can shape our lives today, through how their companies operate, by repaying their obligations to society through taxes on their enormous wealth (at the moment, fairly little), and through their investments in solving the problems that threaten us. Doing that requires imagination. It’s just not the kind depicted on the covers of science-fiction books I, too, read as a child; it's the kind that takes us to expanded universes only to have us think harder about how to understand the one inhabitable place for us in this vast universe—our fragile, pale blue dot—and make it a better place to live.

Utility-Scale Storage of Renewable Energy

[These excerpts are from an article by Andrea Thompson in the December 2019 issue of Scientific American.]

      The way the world gets its electricity is undergoing a rapid transition, driven by both the increased urgency of decarbonizing energy systems and the plummeting costs of wind and solar technology. In the past decade electricity generated by renewables in the U.S. has doubled, primarily from wind and solar installations, according to the Energy Information Administration. In January 2019 the EIA forecast that wind, solar and other nonhydroelectric renewables would be the fastest-growing slice of the electricity portfolio for the next two years. But the intermittent nature of those sources means that electric utilities need a way to keep energy in their back pocket for when the sun is not shining and the winds are calm. That need is increasing interest in energy-storage technology—in particular, lithium-ion batteries, which are finally poised to be more than just a bit player in the grid.

      For decades pumped-storage hydropower, a simple process that features reservoirs at different elevations, has been the dominant large-scale energy-storage method in the U.S. To store energy, water is pumped into the higher reservoir; when that energy is needed, the water is released into the lower reservoir, flowing through a turbine along the way. Pumped-storage hydropower currently accounts for 95 percent of U.S. utility-scale energy storage, according to the Department of Energy. But as efficiency and reliability have improved, and manufacturing costs have tumbled, lithium-ion batteries have surged. They account for more than 80 percent of the U.S.'s utility-scale battery-storage power capacity, which jumped from just a few megawatts a decade ago to 866 mega-watts by February 2019, the EIA says. A March 2019 analysis by Bloomberg New Energy Finance reports that the cost of electricity from such batteries has dropped by 76 percent since 2012, making them close to competitive with the plants, typically powered by natural gas, that are switched on during times of high electricity demand. To date, whereas batteries have largely been used to make brief, quick adjustments to maintain power levels, utilities in several states, including Florida and California, are adding lithium-ion batteries that will be able to last for two to four hours. Earlier energy research firm Wood Mackenzie estimated that the market for energy storage would double from 2018 to 2019 and triple from 2019 to 2020.

      Lithium-ion batteries will likely be the dominant technology for the next five to 10 years, according to experts, and continuing improvements will result in batteries that can store four to eight hours of energy—long enough, for example, to shift solar-generated power to the evening peak in demand.

      But getting to the point where renewables and energy storage can handle the baseline load of electricity generation will take energy storage at longer timescales, which will mean moving beyond lithium-ion batteries. Potential candidates range from other high-tech options, such as flow batteries, which pump liquid electrolytes, and hydrogen fuel cells, to simpler concepts, such as pumped-storage hydropower and what is called gravity storage. Pumped-storage hydropower is cheap once it is installed, but it is expensive to build and can be used only in certain terrain. Similarly simple is the concept of gravity storage, which purports to use spare electricity to raise a heavy block that can later be lowered to drive a turbine to generate electricity….

      The oldest animal remains that almost everyone can agree on are fossils from Newfoundland that date to about 571 million years ago, shortly after the last regional “Snowball Earth” glaciation that encased much of the planet in thick ice. These earliest known representatives of the Ediacaran biota were dominated by soft-bodied creatures up to a meter in height or width. Some took the form of large, featherlike fronds with vertical stalks that rooted them to the seafloor; others sprawled across the ocean bottom, their flat bodies exhibiting a fractal architecture, with branching units that showed the same patterns at all scales. All these body plans maximize surface area, suggesting that these animals absorbed nutrients directly from the surrounding water.

Bioplastics for a Circular Economy

[These excerpts are from an article by Javier Garcia Martinez in the December 2019 issue of Scientific American.]

      Our civilization is built on plastics. In 2014 alone, industry generated 311 million metric tons, an amount expected to triple by 2050, according to the World Economic Forum. Yet less than 15 percent of it gets recycled. Much of the rest is incinerated, sits in landfills or is abandoned in the environment—where, being resistant to microbial digestion, it can persist for hundreds of years. Plastic debris accumulating in the ocean causes all kinds of problems, from killing wildlife when mistakenly ingested to releasing toxic compounds. It can even enter our bodies via contaminated fish.

      Biodegradable plastics can ease these problems, contributing to the goal of a “circular” plastic economy in which plastics derive from and are converted back to biomass. Like standard plastics derived from petrochemicals, biodegradable versions consist of polymers (long-chain molecules) that can be molded while in their fluid state into a variety of forms. The options currently available—mostly made from corn, sugarcane, or waste fats and oils—generally lack the mechanical strength and visual characteristics of the standard kinds, however. Recent breakthroughs in producing plastics from cellulose or lignin (the dry matter in plants) promise to overcome those drawbacks. In an added boon for the environment, cellulose and lignin can be obtained from nonfood plants, such as giant reed, grown on marginal land not suitable for food crops or from waste wood and agricultural by-products that would otherwise serve no function.

      Cellulose, the most abundant organic polymer on earth, is a major component of plant cell walls; lignin fills the spaces in those walls, providing strength and rigidity. To make plastics from those substances, manufacturers must first break them into their building blocks, or monomers. Investigators have recently found ways to do so for both substances. The lignin work is particularly important because lignin’s monomers are composed of aromatic rings—the chemical structures that give some standard plastics their mechanical strength and other desirable features. Lignin does not dissolve in most solvents, but investigators have shown that certain environ-mentally friendly ionic liquids (which are composed largely of ions) can selectively separate it from wood and woody plants. Genetically engineered enzymes similar to those in fungi and bacteria can then break the dissolved lignin into its components….

      Many hurdles must be overcome before the new plastics can be widely used. One is cost. Another is minimizing the amount of land and water used to produce them—even if the lignin comes only from waste, water is needed to convert it into plastic. As with any major challenge, the solutions will require a combination of measures, from regulations to voluntary changes in the ways society uses and disposes of plastics. Still, the emerging methods for producing biodegradable plastic offer a perfect example of how greener solvents and more effective biocatalysts can contribute to generating a circular econmy in a major industry.

Smarter Fertilizers Can Reduce Environmental Contamination

[These excerpts are from an article by Jeff Carbeck in the December 2019 issue of Scientific American.]

      To feed the world's growing population, farmers need to increase crop yields. Applying more fertilizer could help. But standard versions work inefficiently and often harm the environment. Fortunately, products that are more ecologically sound—controlled-release fertilizers—are available and becoming increasingly smart.

      Farmers typically fertilize crops in two ways. They spray fields with ammonia, urea or other substances that generate the nutrient nitrogen when they react with water. And they apply granules of potash or other minerals to produce phosphorus, also in reaction to water. But relatively little of those nutrients makes its way into the plants. Instead much of the nitrogen goes into the atmosphere in greenhouse gases, and phosphorus ends up in watersheds, frequently triggering excessive growth of algae and other organisms. Controlled-release formulations, in contrast, can ensure that significantly higher levels of nutrients reach the crops, leading to higheryields with less fertilizer.

      A class known as slow-release fertilizers has been sold for some time. These formulations typically consist of tiny capsules filled with substances that contain nitrogen, phosphorus and other desired nutrients. The outer shell slows both the rate at which water can access the inner contents to liberate the nutrients and the rate at which the end products escape from the capsule. As a result, nutrients are meted out gradually, instead of in a wasteful, rapid burst that cannot be absorbed efficiently. Newer formulations include substances that slow nutrient delivery still further, by retarding the conversion of starting materials, such as urea, to nutrients.

      Recently fertilizers that more fully fit the description “controlled release” have been developed—made possible by sophisticated materials and manufacturing techniques that can tune the shells so that they alter nutrient-release rates in desired ways as the soil’s temperature, acidity or moisture changes. By combining different types of tuned capsules, manufacturers can make fertilizers that have profiles tailored to the needs of specific crops or growing conditions….

      Although controlled-release technologies make fertilizers more efficient, they do not eliminate all drawbacks of fertilizer use. The products still include ammonia, urea and potash, for example; producing these substances is energy-intensive, which means that their manufacture can contribute to greenhouse gas production and climate change. This effect could be mitigated, however, by using environmentally friendlier sources of nitrogen and incorporating microorganisms that improve the efficiency of nitrogen and phosphorus uptake by plants. There is no evidence that the materials composing the shells hurt the environment, but this risk must be monitored whenever any new substances are introduced in high volumes.

      Controlled-release fertilizers are part of a sustainable approach to agriculture known as precision farming. This approach improves crop yield and minimizes excessive nutrient release by combining data analytics, artificial intelligence and various sensor systems to determine exactly how much fertilizer and water plants need at any given time and by deploying autonomous vehicles to deliver nutrients in prescribed amounts and locations. Installing precision systems is costly, though, so only large-scale operations tend to have them. In comparison, advanced controlled-release fertilizers are relatively inexpensive and could be a front-line technology that would help farmers to sustainably increase crop production.

Teaching the Human Dimensions of Climate Change for 30 Years

[These excerpts are from an article by Pamela Wasserman in the December 2019 issue of Population Connection.]

      There are many excellent teacher resources available to explain climate science, but fewer that address the role that population growth has played in greenhouse gas emissions, or that delve into how vulnerable communities are being impacted by a rapidly changing climate….

      Despite polling that shows 8 in 10 Americans now acknowledge that human activity is fueling climate change, some teachers are still reticent to address the topic, fearing a backlash from parents, especially in politically conservative areas….the emphasis on presenting scientific data and allowing students to draw their own conclusions makes it easier to teach a “controversial” subject….

Climate Change and Contraception

[These excerpts are from an article by John Bongaarts and Regine Sitruk-Ware in the December 2019 issue of Population Connection.]

      Global climate change represents a grave threat to the future of human welfare and our natural environment. The contentious ongoing policy debate about potential interventions focuses on switching to renewable energy sources and increasing energy use efficiency. But given the urgency of the problem and the lack of political will, other approaches to limit greenhouse gas emissions should be given higher priority. Improving access to effective contraception is one such policy that has thus far been largely ignored by the international climate community….

      In 2100, our planet is expected to be home to 10.9 billion people, up from today’s 7.7 billion. This expansion of humanity will take place mostly in sub-Saharan Africa and South Asia. Rapid population growth has pervasive adverse effects on societies, economies, and the natural environment. In particular, with an additional 3 billion people producing greenhouse gases, the global warming problem will become even more intractable in the coming decades.

      …Lack of access to services and the relatively high cost of modern contraceptives are obvious obstacles for poor women, in particular in rural areas of the developing world. Addressing these issues is a key objective of family planning programs which bring services to local communities and provide methods for free or at low cost. However, there are other, often more important, obstacles such as myths about hormones, traditional social norms, and disapproval of husbands. In fact, fear of side effects and dissatisfaction with available methods are often the dominant reasons women are reluctant to use (or continue to use) contraception.

      Social norms dictate how people ought to behave, particularly in traditional societies where patriarchy is dominant; women are expected to follow the decisions of their husbands and community elders. These customs constrain the introduction of new behaviors such as fertility regulation in societies where it has been absent….

Global #ClimateStrike Demands Real Action to Mitigate Climate Crisis

[This excerpt is from an article by Lindsay Apperson in the December 2019 issue of Population Connection.]

      …We’ve already seen the impacts of climate change. Humanity has killed off 60 percent of the global wildlife population since 1970, with human-induced climate change being one of the leading causes. Sea ice in the Arctic has shrunk every decade since 1979. Sea levels are rising, inundating coastal communities, wildfires are ravaging old-growth forests, hurricanes are getting stronger and destroying everything in their paths, and droughts are plaguing farmers and thirsty people around the world.

      Marginalized communities are disproportionately impacted by unfair environmental and climate practices. The Inuit in the Arctic, the Yanomami in the Amazon, the Sioux in Standing Rock, and other indigenous groups across the world are losing their lands and facing negative health implications as a direct result of climate change. In the United States, low-income people and people of color have elevated exposure to pollution from extrac-tive industries (e.g. living near toxic coal plants, causing increased rates of asthma). They are more likely to lack access to clean water (Flint), and they die at higher rates during natural disasters and severe weather events.

      Yet even in the face of the most pressing crisis facing humanity, world leaders are rolling back the few regulations that exist to seriously address climate change. In the United States, Donald Trump reversed environmental regulations, causing a 3.4-percent rise in carbon dioxide (CO2) emissions in 2018—the largest increase since 2010, and the second largest increase since 1996. In Brazil, fires devastated the earth’s largest rainforest—which absorbs nearly one-third of CO2 emissions—largely due to President Jair Bolsonaro's policies that ignored environmental regulations in favor of boosting Brazil's beef industry. Despite demands from climate activists across the world, leaders still have not done enough to address climate change….

Nitrogen Crisis Threatens Dutch Environment—and Economy

[These excerpts are from an article by Erik Stokstad in the 6 December 2019 issue of Science.]

      …They are protesting a Dutch high court decision that in May suspended permits for construction projects that pollute the atmosphere with nitrogen compounds and harm nature reserves. The freeze has stalled the expansion of dairy, pig, and poultry farms—major sources of nitrogen in the form of ammonia from animal waste. Also blocked are plans for new homes, roads, and airport runways, because construction machinery emits nitrogen oxides….

      The government is preparing to enact short-term measures, including lowering a highway speed limit, which could reduce nitrogen emissions a sliver. To make a significant dent, many experts say the country’s farm animal sector—the densest in the world—must shrink and recycle more of its nitrogen. Last month, farmers asked for nearly €3 billion over 5 years to help pay for more environmentally friendly ways to deal with manure. Although agriculture is a large source of nitrogen emissions, other sectors will have to rein in their pollution, too….

      Nitrogen, a key nutrient for plants, is also an insidious pollutant. Fertilizer washing off fields ends up in lakes and coastal areas, causing algal blooms that kill marine life. Airborne nitrogen can also harm ecosystems. One source is nitrogen oxides, mostly from power plants and engine exhaust. In the Netherlands, even more comes from the ammonia vapors from livestock urine and manure. Both kinds of nitrogen react to form aerosols that cause smog, damage foliage, and acidify the soil, hindering roots’ absorption of nutrients. (Dutch farmers must add lime to their fields to fight acidity.)

      The Netherlands is a nitrogen hot spot partly because it is a dense, urbanized nation, although controls on power plants and catalytic converters in autos have helped curb nitrogen oxide emissions. The bigger problem is ammonia emissions from concentrated livestock operations….Dutch agriculture is responsible for nearly half of nitrogen pollution that falls in the country….

      Some scientists and environmental groups say the Netherlands should move to circular agriculture: Farms should only produce as much manure as they can use to fertilize nearby fields; cows should graze rather than be fed nitrogen-rich, imported soy; and pigs and poultry should eat food waste. That would mean 50% fewer animals….

The Pursuit of Earth’s Waters

[These excerpts are from an article by Lydia Barnett in the 29 November 2019 issue of Science.]

      How did climatology become climate science? More fundamentally, how did the idea of Earth as an interconnected natural system—one of the conceptual foundations of climate science—emerge from a welter of different disciplines? In clear and engaging prose, historian Sarah Dry narrates the life stories of six individuals….

      Waters of the World takes readers from the lab to the study to the field and back again….

      The main thread linking these biographies is, as the book’s title suggests, water. Tvndall’s studies of glaciers and experiments with water vapor led him to develop the theory of greenhouse gases. Walker’s failed attempts to develop a science of monsoon prediction fostered instead a dawning realization that interlocking systems of high and low pressure conspired to produce what he called “world weather.” Simpson’s lifelong pursuit of tropical clouds and storms generated novel understandings of atmospheric circulation on a global scale, just as her contemporary Stommel’s work on the Gulf Stream revealed the interconnectedness of the world's oceans. Dansgaard’s fascination with snow and rainwater led him to engineer the method of ice core sampling that proved foundational to the birth of paleoclimatology.

      Dry shows how disappointments and dead ends, creative workarounds, and the contingencies of funding, training, family relationships, scholarly networks, health and mental illness, and access to instruments, institutions, and other people’s labor all shaped scientific inquiry into the planet's oceans, atmosphere, and ice sheets….

      …Waters of the World is a history that functions as a plea for interdisciplinary work on the problem of climate. The book ends with a call to climate scientists to embrace their interdisciplinary roots and to recognize and celebrate that there are “multiple ways of knowing the planet.”

An Even Bigger Climate Problem

[These excerpts are from an editorial by Carolina Schmidt in the 29 November 2019 issue of Science.]

      Holding a major international summit on climate change against a backdrop of civil discontent like the kind that has rocked Chile might have given the world the impression that issues like clean energy can be addressed without also confronting problems of social justice….

      This year, Chile made bold moves to limit climate change. In September, it launched a broad alliance that encourages nations, regions, cities, businesses, and investors to accelerate measures to reduce greenhouse gas emissions and reduce vulnerability to the effects of climate change. And although Chile contributes a mere 0.25% to global carbon emissions, its proposed nationally determined contribution (NDC)—the reductions in greenhouse gas emissions that are at the heart of the international Paris Agreement to limit global temperature rise—was formulated with Chile’s own national agenda of reaching carbon neutrality by 2050.

      Achieving a net zero carbon footprint will require one of the fastest coal shutdowns of any country because the fuel accounts for about 40% of Chile’s electricity generation. The Mitigation Plan for the Energy Sector is aligned with goals set in Chile’s 2050 energy strategy, which has a renewable energy generation target of at least 60% by 2035. Thanks to an Electromobility Strategy, Chile operates the largest electric urban public bus fleet in Latin America, with plans to achieve 100% electric public transport by 2050. These are examples of necessary short-term actions to limit global temperature increase to 1.5°C. In the meantime, a Climate Change Law proposal is under discussion. It is the first Latin American law that formulated a carbon neutrality goal in conjunction with the scientific community. It also proposes a Scientific Council and a Civil Society Council to expand input into policies and a Regional Committee on Climate Change to develop local climate action plans.

      But dealing with climate change will require not only technical and practical transformations in sectors like energy and transportation, but also social transformations. Climate change amplifies social inequities. Sea level rise, droughts, heat waves, and wildfires, among other hazards, affect food, water, air, land, energy, and other securities. Some groups are affected more than others, depending on where they live and their ability to cope. What is needed are “green transitions” that support people who live in poverty and in indigenous communities with limited resources, as well as those in urban communities struck by higher energy costs and air and water pollution.

      How can climate action advance a more sustainable, fairer, and united Chile? Goals, technologies, and policies surrounding climate must be discussed in the context of their impacts across the income distribution. For example, in Chile’s updated NDC, a new aggressive goal to reduce up to 30% of carbon emissions by 2030 was created to address the huge pollution problem associated with cities mainly in the south. The complete coal phase-out program was agreed upon in a roundtable where the government, private sector, local authorities, and civil representatives discussed a transition process that is sensitive to the health and employment of those affected most. And the inclusion of the water security was given priority to address a 10-year drought that has afflicted 70% of the population.

      …Nations cannot address development and prosperity without addressing climate change, and vice versa….

Sidestepping Politics to Teach Climate

[These excerpts are from an article by Ragupathy Kannan in the 22 November 2019 issue of Science.]

      …I teach climate science in my biology classes because I think it’s important to lay out how the climate is changing before I talk about how those changes may impact plants and animals. Some of my students aren’t science majors, so it may be the only time they hear about climate science in a university lecture.

      Recognizing that science doesn’t exist in a vacuum, I also try to make connections between the topics I’m teaching and the wider world. To do that, I set aside a few minutes at the beginning of lectures to talk about science in the news….

      A turning point came the following semester when I received a message from my dean, who regularly reads student evaluations. He had circled a comment from one of my students, writing, “Be careful here.” After thinking it through more carefully, I came to realize that in a polarized political landscape, talking about politicians and the decisions they make is counterproductive. Students may put their guard up, thinking that I’m partisan, and tune me out when I'm lecturing about other things, such as climate modeling. So, I made a conscious decision to change my approach to teaching the subject.

      As part of my modified strategy, I joined a local bipartisan group that aims to bring people together by emphasizing the potential consequences, rather than causes, of climate change. The group taught me about tactful, nonconfrontational ways to discuss climate science.

      Over the past year, I have experimented with my teaching methods, and I have learned that to open my students' minds to the science, I need to find common ground with them. Now, when I discuss climate science news, I focus on things that all of us care about and choose examples that illustrate how climate change might affect their lives. For instance, this summer Arkansas and neighboring states were devastated by catastrophic flooding. It was a topic that hit close to home for all of us, and it gave me the chance to tell my students that major floods are now happening more often than they did in the past.

      Since I altered my teaching strategy, I’ve noticed a shift in my student evaluations. I still get the occasional comment that I’m a “climate doomsdayer,” but overall the evaluations have been much more positive.

      As teachers, we strive to make connections with our students. I’ve learned that delving into the quagmire of politics hinders those connections. But when I instead highlight the ways in which climate change may affect our shared experience on this planet, it’s easier to communicate and connect with all of my students, regardless of their political affiliation.

After 20 Years, Golden Rice Nears Approval

[These excerpts are from an article by Erik Stokstad in the 22 November 2019 issue of Science.]

      Soon. That has long been scientists’ answer when asked about the approval of golden rice, a genetically modified (GM) crop that could help prevent childhood blindness and deaths in the developing world. Ever since golden rice first made headlines nearly 20 years ago, it has been a flashpoint in debates over GM crops. Advocates touted it as an example of their potential benefit to humanity, while opponents of transgenic crops criticized it as a risky and unnecessary approach to improve health in the developing world.

      Now, Bangladesh appears about to be come the first country to approve golden rice for planting….Still, environmental groups haven’t dropped their opposition….And more research will be needed to show the extent of real-world benefits from golden rice.

      Golden rice was developed in the late 1990s…to combat vitamin A deficiency, the leading cause of childhood blindness. Low levels of vitamin A also contribute to deaths from infectious diseases such as measles. Spinach, sweet potato, and other vegetables supply ample amounts of the vitamin, but in some countries, particularly those where rice is a major part of the diet, vitamin A deficiency is still widespread; in Bangladesh it affects about 21% of children….

      Over the past 2 years, regulators in the United States, Canada, New Zealand, and Australia approved golden rice for consumption. There are no plans to grow the crop in these countries, but approval will prevent problems if golden rice somehow accidentally turns up in food supplies….

The Context of Diversity

[These excerpts are from an editorial by Cato T. Laurencin in the 22 November 2019 issue of Science.]

      The term “diversity,” which came about in connection with the passage of the U.S. Civil Rights Act of 1964, has been expanding to include an ever-growing list of identities—from race, gender, and sexual orientation to physical appearance, belief systems, thought styles, socioeconomic status, and rural/urban geographic location, among others. This is a welcome extension of representation, but this added texture has a downside—it threatens to muddle targets and obscure actions when achieving diversity is the goal. This consequence is particularly serious in the context of addressing equity for specific underrepresented racial and ethnic groups….Forging systemic changes that bring Black diversity at all education and career levels will hopefully bring racial equity to practices in these fields and in doing so, expand the benefits of science, engineering, and medicine to society.

      There are unintended negative consequences of the expanded definition of diversity. With so many groups, success in achieving diversity is increasingly measured in a pick-and-choose manner, where progress is defined through any lens that shows success. Also, with so many groups, diversity is often described through the lens of gender, leaving other groups as seemingly less important, or unimportant. And with so many groups, it has become easier for diversity efforts to disregard the historical and present drivers of discrimination that concepts of diversity began with. In other words, the greater context of inclusion and equity can get lost, making strides to diversify meaningless. The latter point is particularly relevant to Blacks in the United States who have experienced slavery, legally enforced segregation and discrimination, and now battle conscious and unconscious racism, and mass incarceration. Institutionalized racism, past and present, has resulted in the disregard, disrespect, and dismissal of Black people from all walks of life, and this is true in science, engineering, and medicine.

      …For example, the number of Black males entering medical school between 2013 and 2014 in the United States was only 500, a historic low. Black men represented only 37.7% of Blacks entering medical school, which represented only 2.5% of all students entering medical school. This occurred during a historic increase in the number of medical schools in the nation….

      In response to this downward trend of Blacks in science and medicine, a number of individuals, including me, convened a U.S. National Academies workshop in 2017 that focused specifically on the growing absence of Black men in medicine in the United States. The ideas became a blueprint for actions that address not only Black men in medicine, but also the trajectory for Black women, and issues in engineering and science overall.

      Embracing the expanding definition of diversity is easy, but using the word with focus so as not to weaken the paths for achieving diversity will take great attention….

Learning to Love Plastic

[These excerpts are from an article by Wade Roush in the December 2019 issue of Scientific American.]

      “Biodegradable” plastic doesn’t do what you think it does. Your paper or metal straw takes only a tiny sip at the problem of plastic pollution. And your supposedly eco-conscious cloth grocery bag is more damaging to the environment than conventional plastic bags—unless you reuse it literally thousands of times. In other words, many of our ideas about plastic and the environment are confused. And that may be getting in the way of the fight against global warming.

      Take the ruckus over single-use plastic bags and straws….The hullabaloo has spurred restaurateurs to roll out cups and utensils made from biodegradable materials such as polylactic acid (PLA), a polyester derived from starchy plants, including corn and sugarcane. The popular myth is that you can safely toss such items onto the forest floor or into the ocean, and microbes will break them down into raw materials that will magically be reborn as daisies or seahorses.

      Not so much. In America and Europe, the technical standards for biodegradability are mostly about industrial composting. Put a plastic bag or bottle into a composting vessel, throw in some microorganisms and turn up the temperature to between 50 and 60 degrees Celsius (122 and 140 degrees Fahrenheit). If 90 percent of the material is released as carbon dioxide within 180 days, then you get to call the item “biodegradable” or “compostable.”

      In other words, a biodegradable material is one deliberately designed to dump its carbon into the atmosphere at the end of its life cycle. Even worse, if biodegradable plastic ends up in an oxygen-deprived landfill rather than a composting facility, anaerobic decomposition will turn it into methane, a gas that warms the planet from 34 to 86 times as much as carbon dioxide. And if you dump biodegradables into the ocean, they break up into tiny bits that choke marine animals long before they degrade appreciably.

      Globally, we produce an eye-popping amount of plastic—some 380 million tons a year, virtually all of it from fossil-fuel feedstocks. So it's understandable why consumers would cling to the comforting 1980s-era idea that plastic can be engineered to disappear back into the environment. But the reality is that 60 percent of all the plastic ever produced is accumulating in landfills or as litter.

      And from a climate scientist’s point of view, that may actually be a good thing. Of course, it’s a crime that so much plastic waste gets into terrestrial and aquatic ecosystems. But we won’t outgrow our need for plastic anytime soon: for one thing, it substitutes for heavier materials in cars and planes, which saves fuel. On top of that—and this is my main point—plastic can function as an artificial carbon sink. If we’re going to extract carbon from the ground at all, far better that it ends up in a soda bottle that will last 400 years than in the combustion chamber of your car.

      If we want to save Earth, we should stop obsessing over biodegradability and invest instead in plastics that are bio-based. Plants use photosynthesis to convert water and CO2 from the atmosphere into sugars, starch and cellulose, all of which can be processed to make plastics. PLA is one of those, but it's designed to be composted, which makes it carbon-neutral at best. The most exciting work in this area focuses on nonbiodegradable plastics such as polyethylene terephthalate (PET), which Coca-Cola uses in its PlantBottle. The current version, introduced in 2009, uses PET that is 30 percent plant-based. Both Coca-Cola and Pepsi have announced bottles made from 100 percent plant-derived PET, although neither has a market-ready version yet.

      The United Nations Intergovernmental Panel on Climate Change points out that to limit global warming to 1.5 degrees C above preindustrial levels, we may need to remove tens to hundreds of gigatons of CO2 from the atmosphere, ideally by 2050. If the world fully converted to nonbiodegradable bioplastics starting in 2020, the carbon sequestered over the next 30 years could amount to more than 10 gigatons—which would be a good start. When it comes to plastic, it's time to think more flexibly.

The Great Molasses Flood

[These excerpts are from an article by Brian Rohrig in the December 2019 issue of ChemMatters.]

      It was a beautiful day in Boston. Even though it was mid-January, the temperature had risen above 4.4 oC (40 oF) by lunchtime, a welcome respite from recent bone-chilling cold. Spirits were high for other reasons, too. World War I had just ended. Bostonians' beloved Red Sox were fresh off a World Series win.

      But on that fateful clay in 1919, the good spirits shattered abruptly when the ground began to shake, and a deafening roar was punctuated by what sounded like machine-gun fire. In short order, anyone within earshot of the blast ran for their lives, if they were able.

      A tank of molasses five stories high had burst, releasing more than 7.6 million liters (2 million gallons) of molasses in a sticky avalanche that enveloped everything in its wake. Buildings crumbled. A fire station near ground zero was destroyed. Steel girders supporting an elevated train bent and twisted. The 1-kilometer (0.62-mile) swath surrounding the tank looked like a war zone.

      At one point, the sticky wave was more than two-stories high, radiating in all directions. It reached a speed of 56 km/h (35 mph), carrying with it shards of jagged metal from the ruptured tank, as well as other debris caught in the flow.

      Unable to outrun the surge of molasses, 21 people died, and more than 100 were injured. Many died from asphyxiation as the thick, sticky fluid filled their lungs. Others were killed by fast-moving debris. Animals also died in the flood—nearly a dozen horses mired in the sweet goo had to be put down, as no amount of effort could free them….

      If you’ve ever tried to pour molasses, you know how slow it is. Molasses is about 5,000 to 10,000 times more viscous than water. Viscosity is defined as resistance to flow—the more viscous the liquid, the slower it flows. Viscosity is highly temperature dependent. A 10 °C drop in temperature can create a threefold increase in viscosity.

      Viscosity comes from the intermolecular forces of attraction acting between adjacent molecules within a substance. Strong intermolecular forces contribute to greater viscosity. If molecules are strongly attracted to one another, they are less likely to flow past each other.

      At colder temperatures, molecules move more slowly and have less energy to overcome intermolecur attractions. This leads to greater viscosity. Think of it this way: Suppose you want to grasp the hands of a person in passing. Running would make this hard to do. But if you are ambling slowly by, it would be easy to join hands, and harder to lose your grip.

      This phenomenon turned a normally useful substance into a deadly one. At first, the distilling company’s molasses flowed out quickly due to warmer temperatures inside the tank, which had been recently filled. But the syrup cooled as it met the wintry air. Its viscosity increased, creating a gooey quagmire.

      The stickiness of the molasses also contributed to the morass. Molasses, being primarily a concentrated sugar solution, clings to just about any surface it encounters. This stickiness is the result of adhesive forces—adhesion is the attraction of unlike surfaces to one another, and is also the result of intermolecular forces. Viscous substances tend to be clingy but not always, since stickiness is dependent on the nature of both surfaces that come into contact. Molasses won’t stick to Teflon, for example.

      Molasses is mostly sugar, and sugar gets sticky when wet. Dry sugar poured from a bag doesn’t stick, but add a little water, and it sticks like glue.

      Sugar molecules’ stickiness is due to polarity. The molecules' protruding hydroxyl groups (-OH) create distinct regions of positive and negative charge. The H side of the -OH group has a partial positive charge, while the O side has a partial negative charge. Sugar readily dissolves in water because the partial positive and negative sides of a polar water molecule will be attracted to the opposite partial charges on a sugar molecule, forming hydrogen bonds.

      When a polar molecule contacts a neutral surface, polarity is induced in the neutral surface as its negative charges are slightly repelled, leaving positive charges at the surface. The negative side of the polar molecule is thus attracted to the now-positive side of the formerly neutral surface.

      To clean up the molasses spill, the affected areas were flushed with salt water from nearby Boston Harbor….

Biome Boost

[These excerpts are from an article by Prachi Patel in the December 2019 issue of Scientific American.]

      Rivers act as Earth’s arteries and veins, providing sustenance and sweeping away waste to keep terrestrial habitats in shape. By that measure, England is unhealthy: a startling 86 percent of its rivers do not meet water-quality standards, posing a risk to wildlife and human health.

      A new study offers hope. Invertebrate biodiversity in one Thames River tributary has increased in the past 30 years, thanks to an adjustment in wastewater treatment….

      Invertebrates such as crustaceans, insects and worms are key players in aquatic ecosystems. They shape their environment by digging into riverbeds and filtering water, and they are both predators and prey. These animals also respond quickly to environmental changes, indicating an ecosystem’s health.

      The researchers analyzed data collected by the U.K. Environment Agency between 1977 and 2017 for a 12-kilometer stretch of the River Ray downstream from a large wastewater treatment plant in the southwestern town of Swindon. They found a steady increase in the variety and numbers of invertebrates since June 1991.

      That timing coincides with the 1991 European Union Urban Wastewater Directive, which pushed treatment plants to switch from filtration to an activated sludge process that uses microbes to break down contaminants. This dramatically cut the organic matter and toxic ammonia going into rivers—and so invertebrate biodiversity slowly improved, the team concluded….

      John Sumpter, an ecotoxicologist at Brunel University London, says this increase most likely boosted diversity among larger creatures, too, and that these results probably apply in other places. Still, published studies showing such improvements are rare….

      …But full restoration will require more work and tougher regulations, he adds, noting the growing problem of agricultural pollution….

Adapt or Mitigate? Both

[These excerpts are from an editorial by the editors in the December 2019 issue of Scientific American.]

      Not that long ago “adaptation” was considered a dirty word among climate activists. Their view was that if we could retool our lives to accommodate the consequences of climate change—rising seas, longer wildfire seasons, and a long list of other not so natural disasters—industries and governments would use that as an excuse to avoid a more important job: curbing our emissions of the heat-trapping greenhouse gases that cause these problems in the first place.

      That position might have been reasonable in 1988, when climatologist James E. Hansen first focused the world’s attention on the threat. Back then there was still time to cut back on emissions in a measured way. More than three decades later, however, we know mitigation didn’t happen. The atmosphere is packed with more carbon dioxide and methane than ever. The most significant reduction effort to date, the much hailed 2015 Paris climate accord, has not yet put a dent in the problem. Climate change is a clearer and more present danger than it has ever been.

      As a result, dismissing adaptation is no longer an option….

      But adapting well takes serious money, and the mechanisms for funding it are misaligned. Many industries and governments, still staving off a systematic overhaul of energy and economic frameworks, are only taking incremental steps to deal with the effects of global warming. One result is that vulnerable communities already experiencing the impact are not receiving adaptation funding from the groups that contributed most to the problem.

      Powerful tools are coming on the scene that could help increase adaptation funding and direct it to those who need it most. Researchers in the emerging field of attribution science, for example, can determine how much climate change is worsening the impact of natural events….

      The focus on mitigation has led to research and debate about the methods, technologies and economics of lowering concentrations of greenhouse gases. But innovations for adaptation tend to be far behind. Ideas for adapting to sea-level rise, for instance, are too focused on “hard” solutions such as seawalls, whereas natural features could be used more widely as protective infrastructure. More cities could be changing their zoning laws to prevent the development of frequently flooded land….

      None of these adaptive actions—which are essential for health, safety and economic stability—diminish the need for a rapid global transition from fossil fuels to clean energy. But they do make climate risk more visible and much harder for politicians and the financial sector to ignore.

What Teachers Know (and Don’t Know) about Learning

[This brief article is in the November 2019 issue of Phi Delta Kappan.]

      A recent survey reveals that teachers’ beliefs about learning do not always match the findings of cognitive scientists. Of the 200 educators surveyed, 97% agreed that people have different learning styles, an idea that has been debunked by scientists. Another myth that teachers endorsed was the idea that people are either right- or left-brained, a belief held by 77% of respondents. Teachers were more skeptical about such myths as the idea that certain kinds of learning are impossible after a certain age, the idea that education cannot help students overcome developmental differences in brain function, and the idea that experience cannot alter a person's mental capacity because it is a genetic trait.

      What about learning strategies that have been endorsed by scientists? A majority of teachers (around 60%) recognized that elaboration (linking new information to old); spacing (spreading out study time, as opposed to cramming the night before), and metacognition (understanding one’s own learning) were effective strategies. However, only 20% of respondents agreed that interleaving (working on a sequence of different types of problems) would be more effective than working on a block of similar problems. Only 31% said that retrieval practice is more effective than rereading, but when presented with a specific classroom scenario, almost 60% preferred the retrieval practice option over rereading.

      According to the report, these findings suggest that findings from cognitive science are not being effectively transmitted to teachers. Because teachers stated on the survey that they get most of their information from professional development courses, conferences, and peers, these avenues are important for sharing the latest science related to learning.

Teacher Stress: Balancing Demands and Resources

[These excerpts are from an article by Christopher Jay McCarthy in the November 2019 issue of Phi Delta Kappan.]

      Teaching is widely recognized to be a stressful occupation, characterized by numerous and varied challenges: administrative burdens, long hours, classroom management difficulties, and lack of autonomy, to name but a few. Teachers are isolated from colleagues for much of the day, spending less than 5% of their work time collaborating with peers….They are also paid less than other workers with similar experience and education, a gap that has grown from 4.3% in 1996 to 17% in 2015, according to the Economic Policy Institute….Further, teachers face significant social and political scrutiny as to how they do their jobs….

      These demands take a toll, resulting in job dissatisfaction, workplace fatigue, burnout, and reduced occupational commitment. The statistics on teacher turnover are grim: Research estimates that between 19°/o and 30% of new teachers leave the field within the first five years of teaching, which can reduce the espirit de corps of their campus community and negatively affect student learning….

      But if it’s clear that teacher stress is widespread, it’s not always clear how teacher stress should be defined. Traditionally, educational policy research has focused on working conditions (i.e., school administration, teacher autonomy, and collegiality with colleagues) as the main driver of occupational health….That is, teacher stress tends to be viewed as a result of working in a stressful environment, often characterized as lacking sufficient funding or effective leadership. However, if only 20-25% of teachers report high levels of stress, then that would suggest that the working environment itself is only part of the issue. In many schools, some teachers are stressed out while others are not; but if working conditions were all that mattered, then every teacher in the school would be equally stressed. Clearly, then, there must be more to the story.

      Chris Kyriacou…and others have argued that teacher stress is better understood as resulting from a mismatch between the pressures and demands made on educators and their ability to cope with those demands. Workforce conditions alone are not sufficient to explain why some teachers are highly stressed. Rather, what matters most is how each teacher sees the demands they face in relation to the resources they have available to meet those demands. Just as beauty is said to be in the eye of the beholder, stress depends on the teacher’s unique view of their classroom. And if this is true, then it should be possible to identify and intervene with teachers who are most vulnerable to stress, above and beyond efforts to improve the larger working environment….

      Of course, on any given day, a teacher might experience some occasions when demands exceed resources and others where the resources meet the demands. Yet, research suggests that it is our overall appraisal that makes the difference: Teachers who chronically find themselves on the losing end of the demand/resource equation are the most vulnerable to stress and most at risk for lowered job satisfaction, greater burnout, and lowered occupational commitment….

How Kappan Authors Have Addressed Stress

[These excerpts are from an article by Teresa Preston in the November 2019 issue of Phi Delta Kappan.]

      Stress and anxiety have no doubt been part of schools since schooling began, but, for decades, they were not frequently addressed….

      In May 1976, Thomas Ringness…took up this idea of anxiety as a fearful anticipatory response to some common event, such as going on stage before an audience, competing in physical education class, taking a test, or visiting the principal’s office. Such fears are common, he argued, and their effects tare not entirely negative….

      …Louis Chandler’s December 1981 article…began with an attempt to help adults understand the child’s perspective when seeking to help them manage stress. Children perceive limits, for example, differently from adults. While adults might chafe against limitations, for children, they create a sense of security and confidence that enables them to seek out new challenges. He also cautioned adults to avoid pushing their own stresses onto children….

      Too often, goals set by outsiders involve factors that are outside students’ (and teachers’) control. And when that happens, said Docterman and Weber, “stress overtakes inspiration. Anxiety replaces optimism….”

      There is no simple way to manage stress in schools, as it arises from so many different sources. But schools can create a climate where mental health is emphasized, and perhaps that will help students and teachers cope….

Everyone’s First Drink

[These excerpts are from an article by Kate Lowenstein and Daniel Gritzer in the September 2019 issue of Reader’s Digest.]

      …The big twist with you humans, of course, is that you figured out how to continue your habit of drinking me well beyond your infancy and into adulthood. And rather than collect human milk and bottle it up, you chose a more efficient lactating creature to supply you: the cow.

      This was an udder stroke of genius. By domesticating a milk-supplying animal—actually, over history, a bunch of them, including sheep, goats, buffalo, camels, and yaks—you found a way to take advantage of otherwise nutritionally useless grasslands and pastures. Ruminants such as cows, sheep, and goats are equipped with multiple stomachs and the (somewhat impolite) habit of regurgitating and re-chewing the contents of those stomachs until they’ve squeezed out every last nourishing molecule. With this unrivaled digestive determination, these beasts manage to turn scraggly weeds into copious amounts of rich and creamy me—and more.

      A milk-producing cow makes on average six or seven gallons of me a day….But studies conducted since the height of fat phobia in the 1990s have suggested that full-fat dairy can be satisfying and decently healthy. Skim milk and low-fat cheese, while lower in calories, just aren’t as satiating.

      The gallon you have of me in your fridge (assuming it’s cow's milk) probably came from an industrial farm, where the cows are often fed grain and corn. Here’s a tip: When you spend a little extra to get a carton marked “from grass-fed cows,” who are out munching their way through pastures, I taste different—some might say better. Further, my flavor will change with the seasons, as the makeup of the grass changes. You might buy the same cheese all year long, but if it’s from pastured cows, its taste and texture will also evolve as spring turns into summer, and so on….

      About 5,000 years ago, a wandering group of you noticed another way I go from perishable liquid to a more long-lasting solid. Shepherds transporting me from field to home would open the bags in which they carried their milk and discover me curdling. There was something about those bags, made from the stomachs of sheep and goats, at work: The stomachs contained an enzyme called rennet, which helps young animals digest their mothers’ milk. Thus began the epic food tradition of making cheese. To this day, rennet from calf stomachs is still used to make many cheeses….

‘Secret Science’ Plan Is Back, and Critics Say It’s Worse

[These excerpts are from an article by David Malikoff in the 15 November 2019 issue of Science.]

      Critics are blasting a revised Trump administration plan to give the U.S. Environmental Protection Agency (EPA) broad power to ignore research results when setting public health rules if officials decide the underlying data are not adequately accessible to the public….

      One issue, critics say, is that EPA wants to greatly broaden the policy's scope, applying it to all studies and data used by the agency and not just the “dose response” studies mentioned in the initial version. The draft also asks the public to comment on whether, in some cases, the transparency rule should be applied retroactively to past studies used to support regulation, potentially opening the door to challenges of existing rules.

      EPA officials have argued that the data transparency policy is needed to ensure that the agency uses only the best “pivotal regulatory science” that can be “independently validated” when crafting “significant” rules that are expected to impose major economic costs. The leaked proposal says EPA regulators should have “the right to place less weight” on certain studies, “to the point of entirely disregarding them,” if the underlying data are “not made available in full to EPA.”

      Critics say that language is primarily designed to weaken regulation by preventing EPA from considering epidemiological and other studies in which researchers have promised to protect the privacy of human subjects. Such confidential health information, which is typically not released to the public, has played a major role in shaping stricter EPA limits on air pollutants. For example, the iconic 1993 Six Cities Study, which linked particulate air pollution to human death and disease, helped spur new EPA soot controls. But some industry groups have long objected to EPA’s use of such “secret science.”

      EPA already has ways to assess the quality of studies and decide which it should consider when writing new rules, notes Chris Frey, a former scientific adviser to the agency and an air quality researcher at North Carolina State University in Raleigh. “But what those methods don’t do is say: ‘Just because there isn’t full public disclosure of the data, we’re going to wipe out and ignore that study, regardless of its quality.’ Doing that would prevent you from considering the full weight of the scientific evidence.”

      The draft acknowledges that full disclosure may not be possible for some studies involving health or proprietary business information; it would empower political appointees at EPA to exempt certain studies from transparency requirements. It also asks for comment on whether EPA should adopt methods, such as those used by the U.S. Centers for Disease Control and Prevention, for only sharing sensitive data with approved researchers.

      But the proposal doesn’t discuss how much such vetting might cost, or how the rule might affect efforts to protect public health….

One Nation under Stress

[These excerpts are from an editorial by Rafael Heller in the November 2019 issue of Phi Delta Kappan.]

      According to Gallup’s…most recent international survey of emotional health, Americans are more frazzled than ever before. On any given day, roughly 55% of us say we feel highly stressed. (Only the citizens of Greece, the Philippines, and Tanzania report higher rates.)

      What’s gotten into us? It's complicated, says the eminent Stanford University biologist Robert Sapolsky, who has spent nearly four decades studying stress, its causes, and its effects. On one hand, stress hormones help humans, like other mammals, respond to immediate physical threats (e.g., hungry lions) and ongoing challenges (e.g., looking for food in the dry season). On the other hand, those hormones also respond to social and psychological conditions. Unlike, say, zebras…, we humans fret about what might happen tomorrow, what happened yesterday, and what didn’t happen at all. We torment ourselves over insults real and perceived. We agonize over threats to our social status. In short, we give ourselves ulcers for a dizzying array of reasons, which have only been amplified by our growing income inequality, declining social cohesion, increasingly sedentary lifestyles, racial tensions, and other political, economic, and societal changes.

      Unfortunately, though, our popular media tend to project a much simpler, one-dimensional version of what stress is and how to cope with it, warns Sapolsky. We Americans tend to think about stress as a personal problem for individuals to “manage” with diet, exercise, yoga, and spa days….

      How, then, should we cope with our stress? That depends, argues Sapolsky, on what’s making us stressed in the first place. (Paying the rent? Impressing our parents? Dealing with climate change?) We shouldn’t expect to find one-size-fits-all solutions, he con-dudes. People need to find the “right strategy for the right time.”

      Today, countless schools across the country are investing in mindfulness programs and wellness rooms. And plenty of research suggests that such programs tend to be helpful. However, by focusing too narrowly on mindfulness and other kinds of stress management, we risk distracting ourselves from the social and institutional forces that are causing so many of us to be so stressed out in the first place.

      …There is much that we can do to make our L schools less stressful places, but first we will need to understand the stressors we face.

Seeking Shared Ground in Space

[These excerpts are from an article by Andrea Ravignani in the 8 November 2019 issue of Science.]

      They shared hits of LSD with dolphins to enhance mutual communication capacities. They suggested that we detonate all existing nuclear bombs on the Moon to create a far-reaching message. They claimed to have received communications from Mars. These individuals, who sound more like characters in a B movie than real people, populate a few of the many fascinating (and true) anecdotes recounted by Daniel Oberhaus in his new book, Extraterrestrial Languages, which chronicles the adventures of scientists who have sought to communicate with extraterrestrial life.

      Oberhaus delivers an engaging read, striking a good balance between “hard” and “popular” science. He reviews centuries of initiatives, combining science with anecdotes, and using linguistics, mathematics, astrophysics, cognition, and art as feedstock. Focusing on practicalities of extraterrestrial communication, he asks: Is it more convenient to send a plaque on a spacecraft or to radio broadcast a mathematical message?

      Presented with these scenarios, the reader realizes a key feature of traditional human communication: It happens in real time. Space messages, on the other hand, might take hundreds of years to reach their intended audience, so they must be self-explanatory.

      A space message should have three features: First, it should be clearly distinguishable from random noise. This could mean sending a signal at specific frequencies and with a character count equaling one prime number times another, so that there is only one possible way to visualize the characters. Second, the message should start by establishing common ground. But choosing universal truths is no obvious task: One overarching question addressed in the book is whether what we call “mathematics,” “language,” and “culture” are absolute or human-relative. Finally, the message should contain information about our planet and us.

      …He defines language as a tool for thinking, not for communicating, borrowing from Noam Chomsky’s theory of generative linguistics. According to this view, humans are the only species with language, a by-product of our language-adapted brains. This all-or-nothing stance sets the bar high, leading him to dismiss, perhaps prematurely, the relevance of animal communication to the discussion….

Laugh Yourself Smarter

[These excerpts are from an article by Adam Piore in the September 2019 issue of Reader’s Digest.]

      …It has been only in the past few years that scanning technologies, such as functional magnetic resonance imaging (fMRI), have let us see how the brain works when it is processing information: which parts do what and what benefits might accrue from exercising different areas. It turns out that joking, long dismissed by some as a frivolous diversion from the serious business of reality, may make us smarter and healthier. There is even some evidence that a sense of humor helps the human species survive.

      To understand why humor is a kind of superfood for the brain, it helps to know what our brains crave in the first place. You might think they’d prefer when we sit alone in a room and stare at a blank wall—we don’t burn up much energy doing that. But the brain is like a muscle, and it needs exercise. What gives the brain a workout? Information. When researchers asked people to look at a series of pictures while their brains were being scanned in an fMRI machine, it was the more complex images—a work of art, a sprawling vista, a group of animals—that tickled the neurons in their heads most.

      It’s the activation of those neurons— nerve cells, which, among other things, send and receive sensory information—that “lights up” the fMRI scans in bright, almost psychedelic colors. In fact, there is an almost druglike effect taking place. The brain is filled with opioid receptors—yes, opioid, as in the drug. Made of specialized proteins, these receptors poke out of our neurons like tiny radio antennas designed to pick up passing signals. When the right kind of molecule bumps into a receptor—perhaps one of the body’s naturally occurring opioids, such as an endorphin, or a synthetic drug designed to look like one, such as heroin or morphine—it can kick off a cascade of brain activity that bathes the neurons in feel-good neurotransmitters and other chemicals. The more neurons that are activated (and the more activated they are), the more pleasure we feel. In essence, learning and problem solving get us high.

      …People who study humor generally agree that most jokes are built around an incongruity—an inappropriate, absurd, surprising, or unusual combination of two fundamentally different ideas or elements….When we first see or hear this mash-up, we’re confused. That’s the setup. The punch line is the resolution of that confusion….

      So in that sense, appreciating humor is not unlike solving a puzzle, and it yields a similar kind of satisfaction. Instead of an aha moment, you get a haha moment. In fact,…because humor requires the brain to process lots of distinct types of information,…funny revelations would activate different and more disparate parts of the brain than unfunny ones. This would excite the neurons even more, which would lead to the release of more neurotransmitters and activation of the reward centers of the brain.

      …When we “get” a joke, the neurons are activated in a quick burst. When we construct a joke, activity in the same brain regions increases slowly as we rack our brains for dissimilar elements that we can link. If appreciating humor is good exercise for our brains, then writing a joke is exercise on steroids.

      Humor helps our cognition in less obvious ways too. Laughter is a natural stress reliever, and our brains work better when they aren’t slowed down by a fog of worry. In 2014, researchers in California demonstrated that elderly subjects who watched a funny video experienced significant improvements in their ability to learn and retain new information, possibly because the feelings of mirth reduced levels of cortisol, a stress hormone that has been shown to hinder recall.

      A good joke can function as a release valve for the whole body….

      …Others have demonstrated that laughter can be associated with increased blood flow, improved immune response, lower blood sugar levels, and better sleep. You don’t have to write a joke to reap the benefits. Merely experiencing humor will do the trick….

Our World in 2050

[These excerpts are from an article by Katharine Gammon in the Autumn 2019 issue of USC Trojan Family.]

      …By 2050, the reality of climate change will no longer be up for debate. The subtle signs we're starting to see around us will be more pronounced, and their impact will be easy to spot in everyday life. The warming trend can feel overwhelming to understand, much less confront—especially with so many factors believed to affect how the planet is changing. But there’s good news: Humanity has tools to shape our future…and some are already working in places across the globe….

      The 20th century was Earth’s warm-est period in nearly 2,000 years….Data he examined from a wide variety of sources, including ice cores, tree rings and coral reefs, show that the warming trend began after the industrial revolution—the 1850s. For the vast majority of the globe, the warmest temperatures have come within the past 100 years. He agrees with the broad scientific consensus that if the trend continues—and physics says it will—sea level rise and droughts could render areas of the planet unsafe or even uninhabitable…

      In the Southern California of 2050, Angelenos could spend a quarter of the year sweating it out in temperatures of 90 degrees or more. That’s 95 days of dangerously hot weather a year, significantly higher than the 67 days we see in 2019. Air conditioning will raise energy bills, but researchers anticipate costs to health as well.

      When temperatures spike, deaths rise too….Research suggests that uncomfortable heat stresses the body, increasing risk of heart problems and stroke, especially in the elderly. High temperatures have also been linked to an increase in pre-term births and infant mortality. Studies on students and stockbrokers and other workers have shown that temperatures above 80 degrees slow down thinking processes, making it harder to focus and make decisions.

      These problems disproportionately harm people with the fewest resources to deal with discomfort and health risks. Several researchers raise the alarm that any climate plan must address society's systemic inequalities….

      We don’t need to travel to 2050 to imagine the impact of climate change on the air. In spring 2018, Los Angeles’ air quality exceeded federal safety levels for 87 days….

      When temperatures rise, so does “bad” ozone. Don’t confuse this ozone with the ozone layer in the upper atmosphere, which shields Earth from the sun’s radiation. Bad ozone forms at ground level when pollutants from cars and other industrial sources react to sunlight….

      By 2050, if climate mitigation strategies and air pollution regulation don’t halt rising temperatures, the skies of Los Angeles could revert to the soupy smog of the 1970s….

      More than 90% of the warming created by humans since the 1970s has been absorbed by the oceans. And just as on land, there is a shift underway in the sea that Lwill affect the global oceans of 2050….

      Numbers of large predator fish have plunged, and about half of the world’s coral reefs have been lost to bleaching caused by warming temperatures….By 2050, most reefs may have vanished, according to a National Oceanic and Atmospheric Administration report. Some governments, like Australia’s, are taking action, trying to protect reefs by reducing other threats to coral such as dredging and runoff from land. And scientists are identifying and growing types of coral that may be better able to cope with warm water….

      Water distribution across the planet is a challenge, too: By 2050, more parts of the world will go through droughts, while others will be deluged with floods….

The Science of Sex

[These excerpts are from an article by Bennett McIntosh in the November/December 2019 issue of Harvard Magazine.]

      The “SINS OF THE MOTHER,” trumpets a headline in the journal Science, warning of a “maternal assault” against children. Another headline calls mothers “smoking guns,” the source of incalculable harm. What wrongs have these mothers committed? Not any sort of physical violence: these articles describe a series of subtle, poorly understood chemical changes, passed from mother to child during pregnancy, that cause obesity and other long-term impairments.

      But such charges stand on shaky ground….

      It’s an idea that dates hack to Aristotle, who declared that mothers had merely to glance at an object to imprint some quality of that object on her child. But in recent decades, scientists using the tools of epigenetics have examined the molecular basis for such claims as never before. Epigenetics (literally meaning “on top of” genetics) is concerned with chemical modifications to DNA that don’t change its sequence, but can still be perpetuated as cells divide, affecting genes’ function in complex but profound ways. It’s a field of compelling possibilities, demonstrating that DNA sequence is not destiny—and putting forward specific chemical explanations for why events during gestation might manifest as health prob-lems later in life.

      …While in utero exposure to specific dangers like the chemical thalidomide or diseases like rubella and syphilis has well-documented effects, those exciting early results seemed to give momentum to far-reaching claims about the dangers (or advantages) of everything from chocolate to the traumas of World War II. These claims routinely reach the public as scientific truth despite their origins in small studies and the even smaller effects they report, and despite study designs that have taken as a given that in utero effects—rather than genetic or postnatal effects—were the only effects worth considering….

      Though “gender,” in popular use, is often simply a synonym for “sex,” for the scientists and scholars who study them; they are distinct. “Sex” is the biological category: the coalescence of genes, hormones, and anatomy shaped by eons, of evolution to differentiate males and females. “Gender” is the cultural category: the “masculine” and “feminine” behavioral expectations and social roles commonly expected of the sexes.

      How did the X and Y chromosomes come to be seen as the essence of biological sex? What does that history mean for the researchers who study them—and everyone who carries them in their cells? How can medical research account for the distinct but entangled influences of sex and gender?...

Why Clean War Is Bad War

[These excerpts are from an article by Anthony Swofford in the November/December 2019 issue of MIT Technology Review.]

      …My lethality increased with each personnel addition: from me, the rifleman, to the four-man fire team, the squad, the platoon, the company, the battalion. Each time, add new men, add new hunger, more firepower, more expertise, more technology with which to lay waste to the enemy. As the fighting organism grows in size, so does the inability to pause mission and, consider whether the killing is just or moral: the killing just is.

      Every generation of American warfighters is handed excellent new gadgets with which to wage war. And who doesn’t love a new toy? Their creators become fabulously rich developing, training the military on, and helping deploy the newest technology….

      During Operation Desert Shield, the Barrett .50 caliber semi-automatic sniper rifle arrived in the Saudi Arabian desert where I and my battalion and tens of thousands of other American forces waited for war with Iraq….

      …With the Barrett we both hit iron targets out at 1,600 to 1,800 yards. The shooting was easy. The shooting was fun. We had been gifted this weapon that extended our dark arts by nearly a thousand yards. The Geneva Convention banned us from using a .50 caliber weapon on a human target, so the official reason the weapons had been released to us was to stop enemy vehicles. But we all knew the best way to stop a vehicle is to kill the driver. The technology told us so. And we listened to the technology….

      Many now profess that the young Marine or soldier with a rifle is obsolete. The greatest weapons race of all is among academic scientists trying to win DARPA funding for new warfighting technology they insist will require scant human interface with the killing act, thus relieving the combatant of the moral quandary and wounds of war. Private-sector startups sell a myth of smart war through AI, or robotic soldiers. In labs where the newest and cleanest ways to kill are being invented, the conversation is not about the morality of going to war, but rather the technology of winning. But when you rely on a myth of technology and distance killing to build a rationale for easy war, your country will lose its soul.

      …we use a $30 million aircraft to drop a JDAM (joint direct attack munition) and kill a dozen guys living in tents on the side of a mountain. What has that $30 million technological advantage bought us? The highly (and expensively) trained aviator piloting a beautifully complex flying and killing machine just extinguished some men living under canvas and sticks, men with a few thousand rounds of small arms ammo at their disposal….

      …And in a draw or valley a few klicks away from where the pilot's munitions impacted, there is another group of men living under extremely basic circumstances, eating boiled rice and maybe a little roasted meat. They will ambush an American convoy or attack a govemment-friendly village in the morning. Native grit debases our technologically superior forces and materiel. Native grit wins a war….

      At the street level, war is a people business. And people are complex. They are also fragile. Their bodies break, crumble, split open, and cease operating with surprising ease when met with the awesome newest war technology. The reality of a war-dead civilian or combatant is not changed by how advanced the tool was that delivered the fatal assault to the body.

      The lust for new defense technology is an insidious attempt to distance ourselves and our leaders from the moral considerations and societal costs of waging war. It’s not so much about the newest tools—swarm drones, exoskeletons, self-guided sniper projectiles. It is that this reliance on technological cool, the assumption that it lessens or alters the lethality of war, allows zero accountability for how, when, and why we fight.

      This is not an anti-intellectual or anti-technology argument. I am not a grunt who thinks wars can only be won with boots on the ground. However, all wars must eventually be won with boots on the ground. The problem is not the technology, but the equivocation that high-tech military armament invariably invites. If fighting war is like swiping your smartphone for an order of groceries or posting a meme to Instagram, how bad can it really be? And if a politician is seduced by the lies and supposed ease of technological warfare and leads us into a mistaken conflict, is it really his or her fault? Didn’t we all think it would be a breeze?

      The moral distance a society creates from the killing done in its name will increase the killing done in its name. We allow technology to increase moral distance; thus, technology increases the killing. More civilians than combatants die in modern warfare, so technology increases worldwide civilian murder at the hands of armies large and small….

      War was supposed to be easy or fast, because of smart bombs and the latest bit of warfighting technology. But this means nothing when years later you only see dead men, women, and children when you try to sleep.

      When we believe the lie that war can be totally wired and digitized, that it can be a Wi-Fi effort waged from unmanned or barely manned fighting apparatus, or that an exoskeleton will help an infantryman fight longer, better, faster, and keep him safe, no one will be held responsible for saying yes to war. The lie that technology will save friendly, civilian, and even enemy lives serves only the politicians and corporate chieftains who profit from war. The lie that technology can prevent war, or even create compassionate combat, is a perverse and profane abuse of scientific thinking.

Masculinity Molecule, Debunked

[These excerpts are from an article by Erika Lorraine Milam in the 1 November 2019 issue of Science.]

      Sexual desire, intelligence, strength, power, and speed. Popular culture would have us believe that these traits and more are enhanced by testosterone. For Rebecca Jordan-Young and Katrina Karkazis, such claims have transformed masculinity into the property of young, white, successful men and made this seem the natural result of a small steroidal hormone.

      Jordan-Young and Karkazis style their book as a daring push from outside the world of testosterone science, challenging long-held assumptions about the hormone….At the heart of their book is a hope of replacing readers’ beliefs that testosterone is merely biological with a nuanced understanding of how both social interactions and internal physiology affect levels of testosterone and its effects.

      Each of the book’s chapters disposes of zombie facts and “undead ideas” about testosterone that have lingered in popular culture despite repeated attempts to vanquish them. The authors label their exploration of testosterone’s influence “unauthorized,” which allows them to explore those narrative threads they find the most interesting—the confounding intellectual spaces rather than the tidy ones.

      Testosterone is not just a male hormone. It appears to play a crucial role in ovulation….

      …people hoped to be able to mobilize testosterone like a personalized precision drug. Reality proved more complicated. As Jordan Young and Karkazis make clear, the entanglements of biology and culture matter.

      These mutual entanglements are at the core of their analysis throughout the book. Risk-taking behavior, for example, has been associated with elevated testosterone in stock brokers, and Jordan-Young and Karkazis query what these results mean when some men, such as coal miners, often take risks out of financial necessity and restricted job opportunities. Risk-taking, they note, is rather less risky for those with high social status.

      Research also indicates that testosterone levels in men drop when they become parents. This might mean that men have evolved a physiological adaptation that shifts their behavior from mate seeking to involved parenting, but Jordan-Young and Karkazis point out that even this claim reinforces stereotypes that fatherhood and other masculine traits function as trade-offs. For athletes, testosterone may help build muscle mass but only in combination with rigorous workouts; the hormone alone has almost no effect.

      In broad prospect, Jordan-Young and Karkazis warn against investing too much in debates over the details of testosterone’s role in determining gender, risk-taking, parenting behavior, and fairness in athletics. They demonstrate in each case that concentrating on testosterone as a molecule draws our attention away from important social and economic sources of systemic inequality”T talk,” as they define it, therefore serves to maintain the status quo as natural. All claims about testosterone, they argue, are power moves in a competitive intellectual landscape….

Stepping out of the Dinosaurian Shadow

[These excerpts are from an article by Riley Black in the 25 October 2019 issue of Science.]

      We live in the Age of Mammals, yet warm-blooded beasts are still over-shadowed by dinosaurs. Even when considering the last great shake-up to life’s story, when an enormous asteroid triggered a mass extinction that decimated dinosaurs and gave mammals a shot at terrestrial expansion, we are often more focused on the terrible lizards lost than the furry creatures who set the stage for the Cenozoic. But a new NOVA documentary—“Rise of the Mammals” —seeks to change that and, in the process, offers viewers a window into paleontology beyond bone hunting.

      …the 1-hour program promises to tell how life surged back after the Cretaceous-Paleogene mass extinction. The catastrophe, we learn, did not just affect dinosaurs. Flying pterosaurs and seagoing mosasaurs disappeared, as did coil-shelled ammonites and huge clams called rudists, along with mass extinctions of birds, lizards, and mammals. But the mammal-versus-dinosaur competition is the film’s primary focus, with images of tiny, shrewlike insectivores living beneath the feet of dinosaurs providing the background for what follows.

      The “Mesozoic mammals as underdogs” trope should be extinct by now. In the past several decades, paleontologists have recognized that mammals thrived during this era, evolving into an impressive array of forms. All were small, fair enough, but so are most of today’s mammal species. To navigate a clear relationship of cause and effect, then, “Rise of the Mammals” emphasizes size. When did mammals start to get big?

      …Instead of following the standard—and often false—story of how a single discovery changes everything, the program follows various threads to assemble a picture of life in the first million years of the Paleocene.

      …the latter half of Rise of the film broadens in scope. “Rise of the Mammals” ends up being a short course in modern paleontology, following the story as it goes back and forth between museum and fossil outcrops. The changing face of paleontology is visible, too; the cast of scientists shown and interviewed is much more gender-balanced and diverse than many programs of the past few decades.

      The Corral Bluffs fossils are phenomenal, and what they have to tell us about the Paleocene is just starting to drip out into the published record, but the ancient ecosystem is only one small part of a global story Where the film shines—and offers something rare—are the moments when the process of science is allowed to unfold, revealing how experts assemble views of lost worlds. And if nothing else, it is helpful to pry the spotlight out of dinosaurian claws now and then.

How Life Blossomed after the Dinosaurs Died

[These excerpts are from an article by Elizabeth Pennisi in the 25 October 2019 issue of Science.]

      …Plants and animals came back much faster than thought, with plants spurring mammals to diversify…

      When the asteroid slammed into Earth, it wiped out 7596 of living species, including any mammal much larger than a rat. Half the plant species died out. With the great dinosaurs gone, 66.0 mammals expanded, and the new study traces that process in exquisite detail.

      Most fossil sites from after the impact have gaps, but sediment accumulated nearly continuously for 1 million years on the flood plain that is now the Corral Bluffs site. So the site preserves a full record of ancient life and the environment.

      Such sites can be hard to date. But Miller, a paleobotanist, and his colleagues collected 37,000 grains of pollen and spores, which revealed a clear marker of the asteroid impact: a surge in the growth of ferns, which thrive in disturbed environments. The site also includes two layers of ash from nearby volcanoes. Volcanic ash includes radioactive minerals whose decay can be used as a precise geochronological clock, providing two time markers. The known flips in Earth’s magnetic poles, which some minerals in the layers had recorded, add detail to the chronology….

      The record confirms the devastation wrought by the impact. Racoon-size mammal species had swarmed the site before the catastrophe, but for 1000 years afterward just a few furry creatures no bigger than 600-gram rats roamed a ferny world where flowering plants, with their nutritious seeds and fruits, were scarce.

      By 100,000 years later, twice as many mammal species roamed, and they were back to raccoon size. These critters foraged in the palm forests that replaced the ferns….

      Over the next 200,000 years, what he calls the “palm period” gave way to the “pecan pie” period, when walnutlike plants arose. New mammals evolved to take advantage of the nutritious seeds. Mammal diversity increased threefold, and the biggest of the new species reached 25 kilograms—beaver size.

      After about 700,000 years, legumes showed up; their fossil pea pods are North America’s oldest discovered to date. Pea and bean species from the “protein bar period” provided protein-rich meals that further boosted mammalian size and diversity….Mammals topped 50 kilograms—a 100-fold increase over those that survived the asteroid. The forests, too, had recovered….

      …no matter what happened to temperature and plant life, the loss of dinosaurs alone might have opened the door to bigger, more diverse mammals….

      The record also holds a sobering message about the future, and how quickly ecosystems might recover from ongoing, human-driven extinctions. Even a recovery that geologists call “fast” took hundreds of thousands of years, and the world was never the same….

Shootings and Social Contagion

[These excerpts are from an article by Zeynep Tufekci in the November 2019 issue of Scientific American.]

      Tragically, more than 20 percent of mass shootings, as tracked by the National Institute of Justice for the past 50 years, have occurred in the past five. The past three have been the deadliest. In the U.S., there is well-deserved attention on the availability of guns (because the deadliness of method and ease of access to weapons matter greatly) and on whether we pay sufficient attention to mental health support for troubled young men.

      But there is one more factor that is only recently getting some of the scrutiny it deserves: the role that social contagion plays in inspiring those troubled individuals to choose this course. People routinely underestimate how social humans are. We all have a viewpoint and an inner life, of course. But in the 20 years since Columbine and other mass shootings, we can say with increasing confidence what is, in retrospect, almost blindingly obvious: the shooters are inspired by those who came before—and how we react to shootings is part of the unfortunate cycle feeding them.

      We can look all the way back to ancient Greece for the archetype: Herostratus, the arsonist who burned down the second Temple of Artemis in Ephesus to immortalize his name, albeit in infamy. As Roman writer Valerius Maximus noted, “A man was found to plan the burning of the temple of Ephesian Diana so that through the destruction of this most beautiful building his name might be spread through the whole world.”

      Indeed, here I am, spreading it. In response to his terrible act, Herostratus was given the damnatio memoriae treatment: he was removedtrom all official historical records, and all public mention of him was banned. The magnitude of his crime, however, meant that he eventually found his way to some accounts nonetheless.

      Contrast damnatio memoriae with our own treatment of mass shooters. Most readers who were old enough when the Columbine tragedy happened almost certainly know the names of the shooters….Even if they are being condemned, they —I are noted, remembered and immortalized.

      Unfortunately, not everyone reacts in horror. The man who murdered 26 people at an elementary school in Newtown, Conn., an almost unfathomable crime, was obsessed with the fame and attention the Columbine shooters received….He then went on to commit his own horror.

      This is not an isolated case. We have quantitative evidence that reveals a spike in such shootings in the period following extensive mass media coverage of one, and reports and law-enforcement investigations show that many shooters study previous shooters, collect news stories about them and study their methods. In a terrible twist, they even focus on the numbers of their victims in an effort to up that count—realizing that the higher the number, the more coverage and attention they will receive in the "rankings," so to speak….

      ….damnatio memoriae may well be the correct method, as hard as it may seem.

      In the modern world, we cannot and should not censor media coverage of the event; however, we can definitely change the way we report it and talk about it. Instead of profiling the murderers, we can focus on the victims….

The Price of Warming

[These excerpts are from an article by Andrea Thompson in the November 2019 issue of Scientific American.]

      When a major heat wave engulfed western Europe in late July, Paris and other cities recorded their highest temperatures ever. The furnacelike weather did not just cause sweaty brows—it also exacted a financial toll in infrastructure damage, lost labor productivity and potentially lower agricultural yields. The situation illustrates how even relatively wealthy countries can take an economic blow from climate change.

      That is a key message of a new study from the nonprofit National Bureau of Economic Research (NBER). Much earlier research has suggested that climate-related losses would be higher for poorer, hotter countries and that colder countries could even see economic benefits from warming. But the new analysis indicates financial suffering will be widespread….

      If greenhouse gas emissions continued to grow along their current trajectory, about 7 percent of global GDP would be lost by 2100, the researchers found. Rich and poor countries, as well as those with hot and cold climates, would all see GDP losses….The U.S. would lose 10.5 percent of its GDP, whereas Canada—which some economists say could benefit from warming because of expanded agriculture—would lose 13 percent.

      Limiting emissions in accordance with the Paris climate agreement (which aims to keep global temperature rise below two degrees Celsius by 2100) would substantially stem the losses. Globally, the decline in GDP would be a mere 1 percent; in the U.S. and Canada, it would about 2 percent.

      Unlike earlier studies, this one looked not just at temperatures but at how they deviate from the normal conditions to which societies have adapted. Although rich countries such as the U.S. may have more resources to compensate for swings away from those norms, the study results make clear that adaptation alone will not prevent major losses….

End Vaccine Exemptions

[These excerpts are from an editorial by the editors in the November 2019 issue of Scientific American.]

      As of late August, there had been more than 1,200 cases of measles across 31 U.S. states this year. It’s a dispiriting comeback for a disease that was declared eliminated in this country in 2000. If the disease has not stopped spreading by the time you read this, the U.S. will likely have lost this status. The illness has been cropping up mainly in pockets of unvaccinated people. Those who choose not to immunize their families are placing at risk not only themselves and their children but also others who cannot be vaccinated because they are too young or have medical issues.

      There isn’t an iota of doubt that vaccines are an overwhelmingly safe and effective way to prevent measles and other diseases, including mumps, rubella, poliomyelitis and pertussis. All 50 states mandate that children entering school get immunized unless they have a medical exemption. Yet almost every state also offers religious exemptions, and more than a dozen offer personal belief/philosophical ones as well. California, Mississippi, West Virginia, Maine and, most recently, New York State have gotten rid of all nonmedical waivers. The others must follow suit. It’s imperative for protecting public health.

      It doesn’t take many unvaccinated people to cause an outbreak. Measles was one of the first vaccine-preventable diseases to reappear because it is so contagious; the threshold for resistance to a disease conferred by sufficient community-wide levels of immunity or vaccination—so-called herd immunity—is 93 to 95 percent. If vaccination levels fall below that threshold, an infected person can cause an outbreak.

      Hesitancy about vaccines is nothing new. People have questioned inoculations since Edward Jenner discovered the smallpox vaccine in 1796. Today vaccines are partly a victim of their own resounding success. People rarely, if ever, see once common diseases such as measles and polio, so they don’t understand their potential danger. On top of that, relentless misinformation campaigns have touted such false claims as the idea that vaccines cause autism….

      Despite the existence of religious exemptions to vaccines, most major faith groups in the U.S. do not prohibit vaccination, and many religious leaders encourage it….

      Many people who choose not to vaccinate believe no government should force them to put medicine into their bodies or their children’s. They frame the choice as a personal right, but they are not taking into account the rights of others, including their own children, to be free of disease. When it comes to balancing the two, we need to consider the needs of the community as well as those of the individual. The Supreme Court ruled in Jacobson v. Massachusetts that states have the authority to require vaccination against smallpox, and in Prince v. Massachusetts it reaffirmed that the right to religious liberty does not include the right to expose a child or the community to disease.

      Some experts argue we should just make it more difficult to obtain religious and philosophical exemptions. But unless the exemptions are removed completely, there will always be people who want to use them. Partial elimination, as the Washington State Senate enacted in the case of philosophical exemptions for the MMR (measles, mumps and rubella) vaccine alone, is also shortsighted because it sends the message that some immunizations are less important than others. The only surefire solution is to eliminate nonmedical exemptions to recommended vaccines.

      People who cannot be vaccinated for medical reasons—such as those with compromised immune systems—should of course remain exempt. But there is no legitimate argument against vaccination for the vast majority of healthy people, and there are many powerful arguments in favor of it. Refusing to vaccinate is not a matter of freedom. It's a matter of public safety.

In Defense of Science

[This excerpt is from an article by Charlie Miller in the Fall 2019 issue of EDF’s Solutions.]

      …Whenever reality collides with the president’s wishes, facts fall by the wayside, from the crowd size at his inauguration to his claim that voter fraud cost him the popular vote. On the environment, however, Trump and his enablers have taken matters to a new level.

      Government scientists have been muzzled, bad data has been used to prop up misguided policies, and research that runs counter to the administration’s id-ology has been censored.

      Exhibit A in Trump’s war on science is climate change, which Trump once labeled a hoax invented in China. Not only did he commit to withdrawing from the Paris climate agreement but he refused to sign an international statement on protecting the Arctic until all references to climate change were scrubbed….

      Trump is taking direct aim at two powerful tools for fighting climate change — the Clean Power Plan and clean car standards. This summer, the EPA completed a full-scale rollback of the Clean Power Plan, designed by the Obama administration to curb carbon emissions from power plants. In August, 22 states and seven cities filed suit to block the rollback….

Exposed: Families at Risk from Oil and Gas Pollution

[This excerpt is from an article by Shanti Menon in the Fall 2019 issue of EDF’s Solutions.]

      …Alexis has uncontrollable bloody noses that arrive unannounced. She gets rashes and bruises that no makeup can cover. Last year she temporarily lost her vision and was unable to walk. Her mother, a nurse, was dumbfounded by her symptoms — until a toxicology report revealed that Alexis had been exposed to benzene, a cancer-causing chemical that is released into the environment by oil and gas activity It’s impossible to prove where Alexis’ exposure happened, but her family's former home in McDonald, Pennsylvania, is near about 20 active oil and gas sites….

      According to a Moms Clean Air Force report, about 10 million people live, and nearly 3 million kids attend school, within half a mile of an active oil and gas site. In 2016, the Mama administration established groundbreaking national safe-guards on climate and air pollution from 36,000 new and recently modified oil and gas wells across the country. These standards…will prevent an estimated 300,000 tons of climate-polluting methane, 150,000 tons of smog-forming chemicals and 1,900 tons of benzene and other hazardous pollutants from getting into our air in 2020 alone. They ensure stronger protections for communities and lay the groundwork for future safeguards on 850,000 older drilling sites.

      The Trump administration tried to prevent these protections from taking effect, an attempt EDF blocked in court. Now the administration is trying to eliminate all federal methane regulation, despite the heartbreaking protests of people like Alexis….

      Some major players in the oil and gas industry are also opposed to the planned EPA rollback. Shell, BP, Exxon Mobil and Equinor have all voiced support for federal methane regulations. These companies and others have set their own methane reduction targets, and some are testing new methane monitoring technologies, which EDF helped develop.

      Ultimately, there’s no substitute for strong federal pollution standards….

A Defining Moment for Democracy

[These excerpts are from an editorial by Randi Weingarten in the Fall 2019 issue of American Educator.]

      …President Trump has trampled rights enshrined in the Constitution and waged a war on truth. He has fanned biases that aim to dehumanize “the other” and that erode our democracy. He is enamored of despots, and distances our allies. He has put commerce and greed over human rights.

      Trump boasts that the economy is the “best ever,” but nearly all of the benefits of economic growth have gone to the wealthiest Americans and large corporations, while millions of Americans tread water. Forty percent of Americans say they couldn’t cover a $400 emergency. More than 28 million Americans are uninsured. Today’s average wage has the same purchasing power as in 1978. The median American family has just $5,000 saved for retirement. Americans hold $1.6 trillion in student debt. And teachers, who routinely spend their own money on supplies for their students, are paid almost 20 percent less than similarly educated professionals.

      Yet Trump is not addressing these problems. Instead, he is stoking America’s divisions in order to exploit them….

      Americans must be clear-eyed about the perilous time we are in. We must think seriously about what we can do to take a stand, and about the implications of doing nothing. We can’t ignore Trump’s bigotry and cruelty, or the fact that his erratic behavior is intended to create chaos and confusion. And we can’t assume things won’t get worse….

Lithium-ion Battery Development Takes Nobel

[These excerpts are from an article by Robert F. Service in the 18 October 2019 issue of Science.]

      You probably have the work of Nobel Prize winners in your pocket. This year's Nobel Prize in Chemistry was awarded last week to the pioneers of the lithium-ion battery, an invention that has become ubiquitous in the wireless electronics that permeate modern life: your phone, tablet, laptop, and perhaps even your car. Lighter and more compact than the rechargeable batteries that preceded them, lithium-ion batteries are now moving beyond gadgets to power homes, airplanes, and even the electric grid that feeds power to entire cities….

      Virtually all batteries have three essential components: two electrodes—an anode and a cathode—separated by an electrolyte. In today’s lithium-ion cells, the electrolyte is typically a liquid that allows lithium ions to move back and forth between the electrodes. When the battery is providing electricity, lithium atoms at the anode give up electrons that flow through an external wire. The positively charged lithium ions left behind migrate through the electrolyte to the cathode, where they nestle between the cathode’s layers of metal oxide materials. Applying an electric voltage to charge the battery reverses the flow, pushing the lithium ions out of the metal oxide, through the electrolyte, and back to the anode, where they retrieve electrons.

      …repeated charging deposited thin whiskers of lithium, known as dendrites, on the anode, causing some batteries to short out and catch fire….

      For starters, battery researchers are working feverishly to do away with cobalt, an expensive metal often mined by child laborers in the Democratic Republic of the Congo, which supplies some 70% of the world’s total. Current lithium-ion batteries reduce the need for cobalt by mixing in manganese and nickel, but stabilizing the layered cathode still requires some cobalt….

      Another major research thrust is replacing liquid electrolytes with polymers and other solid materials. If perfected, solid electrolytes could enable researchers to return to using solid lithium anodes without fear of creating dendrites. That could lead to batteries able to store enough energy to propel electric vehicles as far as gas-powered cars without recharging, power short-hop electric planes, and even store backup electricity from wind and solar plants to light up cities at night and when the wind is still….

Sauropods Get a New Diet and a New Look

[These excerpts are from an article by John Pickrell in the 18 October April 2019 issue of Science.]

      How did sauropod dinosaurs, the biggest creatures ever to have thundered across Earth, bulk up to the weight of more than 10 African bull elephants on a spartan diet of prehistoric greens? Many herbivores today grow fat on energy-rich grasses, but these and other nutritious flowering plants didn’t become common until near the end of the dinosaurs’ reign. Now, researchers think they have glimpsed the answer: a surprisingly nutrient-rich plant that could have been a mainstay of these dinosaurs’ diets, and turtlelike beaks that buttressed sauropods’ peglike teeth as they relentlessly stripped foliage from plants.

      …sauropods were eating machines that gulped down vegetation without chewing. They swung their long necks over vast areas, like prehistoric lawn mowers, while saving energy by keeping their bodies in one spot. The new studies add detail by exploring the beasts’ diet and jaw structure.

      …identified what may have been the superfood of the dinosaur era. Her team zeroed in on the nutritional content of low-growing, spore-bearing horsetails, or Equiserum, which were widespread during the Jurassic period and still grow today.

      Horsetails appeared to be poor fodder in previous tests, which simply burned the plants to measure carbon content….They fermented modern horsetails for 3 days to simulate the journey through a sauropod's gut and measured the volume of gas produced—an indicator of energy content. The researchers were astounded to find that horsetails released more energy than any other plant group, including 16 modern grasses. Equisetum is rich in protein, they say, and far more nutritious than the ferns, cycads, and conifers common in the dinosaur era….

      Even eating superfoods, sauropods must have vacuumed up as much as 1 ton or more of plant matter per day. To understand the mechanics, another Bonn team analyzed the beasts’ jaws.

      For decades, paleontologists have dug up puzzling fossils: rows of isolated sauropod teeth, still neatly arranged as they would have been in the mouth, with not a scrap of bone encasing them….

      …Instead of the lizardlike lips shown in artists’ concepts, the behemoths likely sported beaks as well as teeth, unlike any living animal.

      The researchers found that sauropod teeth typically show surface wear only about halfway down to the jaw. That suggests the teeth were once deeply embedded in a supporting structure. The researchers also found tiny pits in the surface of the jaw, perhaps indicating blood vessels to nourish beaks. Similar pits and foramina are seen in other dinosaur bones near inferred structures, like the sheaths covering horns, thought to have been made of keratin, which forms our nails and birds’ beaks and feathers.

      Poropat cautions that expanded gum tissue, rather than a beak, might have held the teeth in place. But bony scaffolding that supported beaks is obvious in other dinosaurs, including Triceratops, Stegosaurus, and duck-billed hadrosaurs….

Bringing Clarity to Science Instruction

[These excerpts are from an article by John Almarode, Douglas Fisher and Nancy Frey in the October 2019 issue of The Science Teacher.]

      Through teaching science, we have the pleasure of developing and implementing learning experiences that allow students to discover how the world works….Interweaving the laws, principles, and theories of the universe with scientific practices that have allowed scientists to discover these ideas is the focus of teaching and learning in the science classroom. The overall intention is that learners will walk away with the ability to engage with science-related issues, and with ideas and processes or practices of science beyond the walls of the classroom—the definition of scientific literacy….We want our learners to take ownership of their learning in pursuit of knowing and understanding things in the world….

      The learners in these classrooms are just waiting to be entertained by the demonstration, checking off the steps in a laboratory investigation, memorizing discrete facts, doing science only when they are in the science classroom, and learning textbook definitions of words. These situations do not provide an authentic context that is relevant to these adolescent learners. What results is that students are no closer to three-dimensional learning (science and engineering practices, disciplinary core ideas, and crosscutting concepts) as envisioned by the National Research Council and articulated in the Next Generation Science Standards, much less scientific literacy….

      Planning and implementing cohesive science learning experiences that build and utilize science knowledge to explain phenomena, while at the same time drawing on problem-solving within that context is more than just clarity. However, without clarity about learning, students are less likely to make meaning of these experiences, and thus not engage in working toward the learning intentions or goals in the science classroom….

      Clarity refers to the overall awareness of the teacher and the learners regarding what the science learning is for that day or class period, why we are learning this science content or engaging in these practices of science, and what successful learning looks like. Put differently, for learners to have clarity in the science classroom simply means they must know the what, why, and how of the day’s learning….

Deforestation

[These excerpts are from an article by Chris Anderson in the October 2019 issue of The Science Teacher.]

      From the boreal forests in Siberia and Canada to the temperate deciduous forests of eastern North America and Europe to the tropical rain forests that encircle the Earth’s equator, forests occupy nearly a third of the land surface on our planet and provide a foundation for nearly all terrestrial ecosystems.

      This month, the world watched in stunned disbelief as wildfires broke out across 5.5 million acres of the Amazon rainforest. Dry weather, wind, and heat has burned up an ecosystem already under threat from agriculture, logging, and mining.

      Sadly, the inferno raging in one of the last few treasure troves of biodiversity on our planet is not an isolated ecological disaster. Wildfires are consuming wilderness in Siberia, Indonesia, Central Africa, and Alaska. Fires are not the only cause, however. Our forests are being cut down at an unprecedented rate.

      Whether it’s for expanding agriculture for cattle and palm oil, mining, or human development, an area equal to 27 soccer fields of the Earth's forests is destroyed every minute. Approximately 18.7 million acres of forest are felled annually, larger than the island of Ireland. In the last few months, Brazil has opened up even more of the precious remaining Amazon to resource extraction.

      …Getting our students to see the relevance of forest being destroyed thousands of miles away when the impacts may not be felt in their daily lives is our biggest challenge. The key is to highlight how fewer forests, whether it’s down the street or on another continent, will make their air and water dirtier, make them sicker, and make their world a hotter place to live.

      …Understanding how the global economy affects the natural world is a great way to show deforestation’s impact on students’ lives and offers many potential cross-curricular projects for willing history and social studies teachers.

      After giving the students some background on the causes and impacts of deforestation, the easiest and most obvious application is in biology, where teachers can use deforestation as a theme for discussing biodiversity, populations, tro-phic levels, and biogeochemical cycles….

      Energy cycling throughout ecosys-tems is another excellent concept to apply to deforestation….

      Understanding the human impact on the environment may be the most important lesson we teach our children. When kids understand that forests make our world a cleaner, cooler, healthier, and more peaceful place, they will fight to protect it….

Bad Bites

[These excerpts are from an article by Steve Mirsky in the October 2019 issue of Scientific American.]

      …Most people are probably more frightened of sharks than they are of mosquitoes—it's tough to get too worked up over something you can swat. But as author Timothy Winegard points out, sharks kill fewer than 10 people annually, whereas the average yearly mosquito-related death toll over the past two decades is about two million. Mosquitoes are the deadliest predator of people on the planet.

      The runner-up killer of human beings is—you guessed it—human beings. In that same stretch, we’ve offed about 475,000 of our fellows on average annually….Granted, it would be tough for 7.7 billion humans to outkill the 110 trillion mosquitoes that are alive at any time. That's more than 14,000 of them for every person. In the Arctic during the summer, they can completely cover something (or someone) edible in a flash. “Ravenous mosquito swarms,” Winegard writes, “literally bleed young caribou to death at a bite rate of 9,000 per minute, or by way of comparison, they can drain half the blood from an adult human in just two hours.”

      Of course, human expiration via exsanguination by mosquito is exceedingly rare. “It is the toxic and highly evolved diseases she transmits that cause an endless barrage of desolation and death.” Winegard writes. He uses “she” because only females bite, attracted to us mostly by the carbon dioxide exhalations that they can detect up to 200 feet away. They also like really smelly feet. So if you think you can hide in plain sight by holding your breath, be sure to also wash between your toes before you pass out.

      Of the more than 15 diseases mosquitoes transmit, the deadliest—malaria—has been sickening animals for an exceedingly long time. “Amber-encased mosquito specimens contain the blood of dinosaurs infected with various mosquito-borne diseases, including malaria….”

      The book claims that mosquito diseases played a critical role in the American colonists' underdog win in 1783 against the British in the Revolutionary War. George Washington, himself a malaria sufferer, “had the advantage of commanding acclimated, malaria-seasoned colonial troops.” Meanwhile many British troops had never been exposed and were mowed down by the kill-buzz….

Smart Start

[These excerpts are from an article by Lisa Guernsey in the October 2019 issue of Scientific American.]

      …In many preschool classrooms in the U.S., children are asked to do little more than identify shapes and letters and sit quietly on rugs during story time. But a growing body of research is overturning assumptions about what early education can look like….when children learn certain skills, such as the ability to focus attention—skills that emerge when teachers employ games and conversations that prompt kids to think about what they are doing—the children do better socially and academically for years afterward. A study published last year, which tracked kids for a decade starting in preschool, found some evidence that children with teachers trained to foster such abilities may get better grades com-pared with children who did not get this type of education.

      Politicians routinely promise to give more money to prekindergarten schooling….But experts say that to do right for kids, any program will need to focus on at least two foundational skills: executive functioning and oral language.

      Executive function involves a suite of cognitive skills, such as being able to hold an idea in one’s head and recall it a short time later (working memory), the ability to control impulses and emotions, and the flexibility to shift attention between tasks. Oral language skills mean not just expressing sounds and words but using them in meaningful conversations that involve increasingly complex sentences.

      …a few decades ago cognitive scientists and behavioral researchers began to examine how and when children develop the ability to “self-regulate”--to know when to control emotions and how to follow through on tasks even when they might be difficult….(The term “self-regulation” some-times is used interchangeably with “executive function.”)

      …Opportunities to practice independence and autonomy may be another key ingredient. A 2018 study in the Journal of Applied Developmental Psychology links improvements in children’s executive function to the extent to which adults give them a little autonomy….

Monsters of the Mesozoic Skies

[These excerpts are from an article by Michael B. Habib in the October 2019 issue of Scientific American.]

      …Pterosaurs were the first vertebrate creatures to evolve powered flight and conquer the air—long before birds took wing. They prevailed for more than 160 million years before vanishing along with the nonbird dinosaurs at the end of the Cretaceous period, around 66 million years ago. In that time, they evolved some of the most extreme anatomical adaptations of any animal, living or extinct. The smallest of these aerial predators was the size of a sparrow. The largest had a wingspan that rivaled that of an F-16 fighter jet. Many possessed heads larger than their bodies, making them, in essence, flying jaws of death. Pterosaurs patrolled every ocean and continent on Earth. No animal in the Mesozoic would have been safe from their gaze.

      Unlike dinosaurs, which are survived today by birds, pterosaurs left behind no living descendants. As a result, all that paleontologists know about pterosaurs comes from the fossil record. And that record has been frustratingly fragmentary, leaving us with just a glimmer of their former glory and a host of questions about their bizarre anatomy and ill fate. Paleontologists have scratched their heads over these mysteries for decades. Now new fossil discoveries, combined with mathematical modeling methods in which anatomical structures are simplified just enough that equations of physical properties can be applied to get best estimates of strength, weight, speed, and so forth, are finally generating insights. And what scientists are finding is that pterosaurs were even more extraordinary than we ever imagined….

      One of the enduring mysteries of pterosaurs is how the largest members of this group became airborne. Giants such as Quetzalcoatlus, first discovered in Texas, and Hatzegopteryx, from modern-day Romania, stood as tall as a giraffe and had wingspans of more than 30 feet These animals possessed jaws twice the length of those belonging to Tyrannosaurus rex. Their upper arms would have been nearly as large around as the torso of an average-sized adult human. They were true behemoths, attaining weights exceeding 650 pounds. For comparison, the largest bird to ever take to the air—Argentavis, living six million years ago in Argentina—most likely weighed less than 165 pounds.

      The discrepancy between the biggest members of each of these groups is so vast, in fact, that multiple researchers have suggested that the largest pterosaurs could not fly at all (although this would be puzzling given their many anatomical adaptations for flight). Others have suggested that they could fly but only under very special air and surface conditions—if the atmosphere in their day were denser than it is today, for instance. After all, it seems unfathomable that birds of such sizes could fly. In fact, recent power-scaling studies from several researchers, including me, have demonstrated that supersized birds would have insufficient power to launch themselves into the air in the first place.

      But pterosaurs were not birds. Indeed, over the past decade my colleagues and I have carried out numerous calculations of pterosaur launch and flight power, showing not only that giant pterosaurs could launch and fly but also that they probably did not need any special circumstances to do so. In line with these conclusions, we now know from geochemical analyses of sedimentary rocks and microanatomical analyses of plant fossils that air and surface conditions in the Late Cretaceous—the heyday of enormous pterosaurs—were not remarkably different from what we experience today. What was different, and unique, was the anatomy of pterosaurs.

      There are three things that an animal needs to be able to fly at gigantic sizes. The first is a skeleton with a very high ratio of strength to weight, which translates to a skeleton with large volume but low density. Pterosaurs and birds both have such skeletons: many of their bones are quite hollow. The walls of the upper arm bone of Quetzalcoatlus, for example, were about 0.12 inch thick—comparable to an ostrich eggshell—yet the bone had a diameter of more than 10.5 inches at the elbow.

      The second thing that a giant flier needs is a high maximum lift coefficient. This number describes how much lift the wings produce for a given speed and wing area. At a high lift coefficient, an animal can be heavier because its wings will support more weight at a lower speed. This relation, in turn, means the creature needs less speed on takeoff, which makes a huge difference in the muscle power required for launch. Membrane wings, such as those of pterosaurs and bats, produce more lift per unit speed and area than the feathered wings of birds. This additional lift improves slow-speed maneuvering capability, which for small animals helps with making tighter turns and for big animals facilitates takeoff and landing.

      The third and most important prerequisite is launch power. Even with very efficient, large wings, a big flier still needs to produce lots of leaping power to become airborne. Flying animals do not flap their way into the air or use gravity to take off from an elevated location such as a cliff. Wings do not produce much lift at low speeds, and gravity launching would mean trying to take off by accelerating in the wrong direction—a dangerous prospect. Instead, a powerful jump provides critical speed and height to begin flight. Increased leaping power yields better launching power. Large fliers therefore need to be good jumpers.

      Many birds can manage impressive leaps. They are constrained by their heritage as theropod dinosaurs, however: like their theropod ancestors, all birds are bipedal, meaning they have only their hind limbs to use for jumping. Pterosaurs, in contrast, were quadrupedal on the ground. Their wings folded up and served as walking, and therefore jumping, limbs. Numerous exquisitely preserved fossil trackways confirm this odd aspect of pterosaur anatomy. Being quadrupedal drastically changes the maximum size of a flying animal. Pterosaurs could use not only their hind limbs for launch but also their much larger forelimbs, thereby more than doubling the available power for takeoff. They had the perfect combination of adaptations to become aerial behemoths.

      Previous studies have modeled bipedal launches for giant pterosaurs. For example, in 2004 Sankar Chatterjee of Texas Tech University and his colleague worked out how Quetzalcoatlus could propel itself into the air using only its hind limbs. But the researchers determined that for that approach to work, the animal could not weigh more than 165 pounds and had to run downhill into a headwind. The quadrupedal launch allows for more realistic body weight and less restrictive environmental conditions.

      …The proportions of pterosaurs are downright bizarre. All pterosaurs had oddly proportioned limb elements. Their hands, for example, are probably the most specialized in all of the vertebrate world, with an immense fourth finger that supported the wing. Yet this is not especially surprising in and of itself because that unusual hand was intrinsic to the pterosaur wing and the animal’s ability to fly. What really confuses scientists and enthusiasts alike is not the wings of pterosaurs but the heads.

      Even early pterosaurs had decidedly large noggins. The head on Rhamphorhynchus, a representative species from 150 million years ago, in the Late Jurassic period, was nearly as long as its body. Then in the Cretaceous head size got even more extreme. Fossils of species such as Quetzalcoatlus, as well as Anhanguera from Brazil, show that pterosaurs got bigger on average, but their heads became proportionately gigantic. The skull on a rather typical Cretaceous pterosaur might be two or even three times the body length (usually taken as the distance between the shoulder and hip). Some had skulls surpassing four times the length of their bodies. The braincases on these animals were not terribly large, though. It is mainly the faces and jaws that expanded to an outrageous degree. Bony flanges under the jaw, towering crests atop the cranium and other elaborations further exaggerated pterosaur skull anatomy. In all, the head could almost seem like it was from a different animal than the body.

      The oddities do not end there. Whereas in most animals, including humans, the bones of the neck are among the smallest in the spine, the neck vertebrae in pterosaur specimens are often the largest. In fact, the neck vertebrae are often twice the volume of the vertebrae in the torso. One of the newest additions to the pterosaur family tree offers a great example of this trend….It has neck vertebrae that are nearly as long and twice as strong as its humerus, the wing bone to which most of the flight muscles attach and that does most of the work to keep the animal up in the air. In some species the neck is triple the length of the torso, with the head size triple again, such that the head and neck could make up more than 75 percent of the total length of the pterosaur. Why would any animal be so ridiculously proportioned? And how could such a body plan possibly work for a flying creature?

      Specialists are still working out why pterosaurs ended up with such crazy anatomy, but one probable explanation is what I call the “if it were easy, everyone would do it” hypothesis. In short, having a big set of jaws to eat with and a big face with which to signal to mates and rivals might be a great option for a lot of animals if the costs associated with these traits were not normally so prohibitive. For example, mammals have big braincases, so mammal heads become very heavy as they grow larger in overall dimensions. Pterosaurs might have stumbled into a developmental zone where the proportions of the face were less coupled to those of the back of the skull. This would have allowed them to evolve a giant set of jaws without having a huge braincase.

      Pterosaurs also had extra openings in their skulls, the large of which was an opening in front of the eyes known as an antorbital fenestra. Dinosaurs had this opening, too, but pterosau took it further, in some cases evolving an opening so large that the torso skeleton could have fit inside it. This opening would have been covered with skin and other tissues in life and probably would not have been visually obvious, but it made the skull quite light relative to its volume. The bones of the skull might also have had large air spaces within them, similar to the air-filled skull bones of some living birds.

      Even with these weight-saving features, however, pterosaurs’ heads were often so colossal that they still would have been quite heavy. Perhaps counterintuitively, the fact that they were flying animals may have worked in their favor in this regard. The main problem with a heavy head is not the overall increase in body weight. Rather it is the disproportionate effect that the skull weight has on the animal’s center of gravity. A huge head, especially if mounted on a huge neck, moves the center of gravity quite far forward. For a typical walking animal, this creates a serious problem with gait: the forelimbs have to move into an awkward forward position for the animal to be balanced. But pterosaurs had enormous forelimbs purpose-built for flight.

      …when a pterosaur was walking, those forelimbs were positioned just about right to take up the weight of the head, neck and chest. Most of the propulsion dur ing walking came from the legs, so pterosaurs could hold the weight of their hefty heads on their extrabulky arms and push themselves along with their much more normal-sized hind limbs….

      This arrangement would not have made for the most efficient walking gait, but it was doable. And anyway, pterosaurs traveled primarily by flying. Pterosaur species with especially long, narrow wings, like those of some modern seabirds, might have flown continuously for months or even years, touching down only to mate or lay their eggs. The pterosaur Nyctosaurus may have had the most efficient wings—and thus the longest continuous soaring flight—of any vertebrate animal ever.

      In the air, the center-of-gravity problem becomes much easier to deal with. For an animal to be stable in the air, its center of lift and center of gravity must be in alignment. This might seem like a difficult prospect for a creature with a supersized head and a correspondingly forward center of gravity. But a pterosaur’s center of lift was close to the front of a wing, which means that the animal needed only to angle its wings moderately for-ward from the root to align the center of lift with the center of gravity….Forward-swept wings can themselves be sources of instability, but the flexibility of pterosaur wings and the rapid cerebellar reflexes that all vertebrate creatures possess could have compensated for it….

      Why did pterosaurs suffer a fate worse than that of the birds at the end of the Cretaceous? One reason might be their tendency to grow large. Hardly any land animals with an adult body mass of more than 44 pounds survived that apocalyptic time….When the asteroid struck, it vaporized part of Earth’s crust, along with much of itself, and the reentry of this superenergized rock-metal cloud essentially set the sky on fire around the world….global soaring conditions might well have been ruined for a month after the impact—enough time to starve every pterosaur that needed to soar to eat….

      Although it ends with extinction, the story of pterosaurs is one of success: they were the ultimate aerial giants, having evolved a dazzling array of extraordinary anatomical features not seen in any other group before or since. From them we have learned much about the limits of animal form and function. Those lessons help us understand the history of Earth and the complexity of ecology. They are even inspiring new technologies, including novel aircraft designs. Their fossil record is a thrilling window into a bygone world filled with real flying monsters. Pterosaurs were not just extreme—they were exceptional.

The Precautionary Tale of Golden Rice

[These excerpts are from an article by Andrew J. Wright in the 11 October 2019 issue of Science.]

      The term genetically modified organisms (GMOs) inspires images of crazy crops: a single plant that bears tomatoes above ground and potatoes beneath, or a tree that bears a fruit with stripes of yellow sour orange and green stripes from citron. Unlikely as they may sound, the two plants described above are very real, although neither was made in a laboratory. They are products of simple grafting, a technique used by horticulturalists for thousands of years. In Golden Rice: The Imperiled Birth of a GMO Superfood, science writer Ed Regis explores why certain food plants are treated by regulatory authorities and the public as “genetically modified,” and therefore worthy of strict cautionary regulation, whereas others are seen as “natural,” despite intensive human intervention in their growth and development.

      The book’s title refers to rice whose yellow grains have been genetically altered to express beta-carotene to address the widespread problem of vitamin A deficiency, symptoms of which include frequent infections, blindness, and even death. Vitamin A deficiency is estimated to affect one in three children under the age of 5, claiming 670,000 lives every year. The idea behind golden rice was that expressing beta-carotene, a vitamin A precursor that occurs in other parts of the rice plant, in the grain, would facilitate the delivery of the vitamin to children in Africa and Southeast Asia, whose main diet is rice.

      Golden Rice is a thoughtful and carefully documented tale of how difficult it can be to take something that works in the laboratory and get it to the people who stand to benefit from it. Regis puts his cards on the table from the start, dedicating the book to the scientists who led the development of golden rice. But he also makes clear that these researchers were responsible for some of the missteps that thwarted the rice’s journey….

      From a scientific standpoint, the technology was a success. So, what prevented golden rice from being quickly disseminated? Although Greenpeace and other anti-GMO activists have been vocal critics of the project, Regis also points to another culprit: the Precautionary Principle.

      The Precautionary Principle, cited in the Cartagena Protocol of 2000 (an international agreement on biosafety), allows countries to restrict, postpone, or ban any product or technology without offering any evidence that the item poses a threat or danger—“better safe than sorry” writ large. Many years of the Golden Rice Project have thus been spent attempting to comply with stringent regulatory hurdles….

      Although nuclear energy has Chernobyl and pharmaceuticals has thalidomide, Regis points out that no such disaster exists for GMOs. (A suspected link between Monarch butterfly decline and Bt corn might have fit the bill, but these claims were later debunked by numerous studies.) While one could argue that it is better to be proactive than to wait for a tragedy to occur before taking precautions, Regis invites the reader to consider whether it may be worth the unknown risks ostensibly being prevented by regulation to prevent the death and disability that is known to accompany vitamin A deficiency.

      After millions of dollars and years of effort, the United States, Canada, Australia, and New Zealand have all recently approved golden rice as safe for consumption. Now, the end goal is in sight: Golden rice is in front of regulators in the Philippines and in Bangladesh, where it is expected to Lbe approved by the end of 2019.

Confronting Climate Change

[These excerpts are from an article by Miriam Aczel in the 11 October 2019 issue of Science.]

      …In On Fire, writer and activist Naomi Klein distills the development of the climate change mitigation movement over the past decade into a series of thoughtful essays that poignantly highlight the dire situation of the planet. At the same time, she chronicles the unfolding of a “people’s emergency;” characterized by tidal waves of climate-focused civil disobedience.

      The largest threats—rising sea levels and increased flooding, droughts and famines, rising global temperatures, and increasing extreme weather events—are also harming livelihoods, deteriorating services and wages, and disproportionately affecting the poor. We have a “once-in-a-century chance to fix an economic model that is failing the majority of people,” Klein argues. And although the transformation would require ending current consumption patterns, confronting the climate crisis, Klein contends, would lead to creation of millions of good jobs, guaranteed health care, and opportunities for the most “systematically excluded” populations.

      A key threat to concerted action is climate skepticism, coupled with a drastic shift in the intensity of emotional responses related to climate issues. When challenging a person’s position on an issue means challenging a central tenet of their identity, facts can be perceived as attacks and are easily deflected. Klein maintains, however, that enhancing communication and tying climate change to other concerns, including the economy and social justice, will help mitigate these threats.

      Amid increasing tension between climate advocates and those disavowing climate change, a shift in values is occurring. Today’s activists understand that to change environmental policy requires confronting the values of “rampant greed and individualism” that led to the economic crisis. Social change, Klein contends, begins with radically altering how we relate to each other (and to nature), accepting our collective responsibility to future generations, and respecting the interconnection of all life.

      …In The Green New Deal, Rifkin confronts skepticism about the feasibility of making a transition of the scale required by countering that we are already making these changes in many global regions. It is time, he argues, for the United States to join the E.U. and China as leaders toward a zero-carbon economy.

      …we are currently entering the “green digital Third Industrial Revolution,” a paradigm shift in which ownership is replaced with access. The “sharing economy”—made possible by digital infrastructures of energy, communication, and mobility—is, he argues, the first economic system to have emerged since capitalism and socialism. Although the federal government will play a crucial role in framing the transformation, he writes, in today’s increasingly “laterally distributed glocal era,” municipalities and local counties are particularly equipped to play an important role.

      …a “carbon bubble” —in which fossil fuel prices will be reduced to compete with renewable prices-- would lead to economic and environmental damage if not deflated early. He believes that we can avoid this with rapid decarbonization….

Obesity on the Brain

[These excerpts are from an article by Ellen Ruppel Shell in the October 2019 issue of Scientific American.]

      …Among those views is the idea that particular nutrients such as fats, carbs or sugars are to blame for our alarming obesity pandemic. (Globally the prevalence of obesity nearly tripled between 1975 and 2016, according to the World Health Organization. The rise accompanies related health threats that include heart disease and diabetes.)….a dramatic shift in how we make the food we eat—pulling ingredients apart and then reconstituting them into things like frosted snack cakes and ready-to-eat meals from the supermarket freezer—bears the brunt of the blame. This “ultraprocessed” food…disrupts gut-brain signals that normally tell us that we have had enough, and this failed signaling leads to overeating.

      …His first study found that, contrary to many predictions, a diet that reduced carb consumption actually seemed to slow the rate of body fat loss. The second study, published this year, identified a new reason for weight gain. It found that people ate hundreds more calories of ultraprocessed than unprocessed foods when they were encouraged to eat as much or as little of each type as they desired. Participants chowing down on the ultraprocessed foods gained two pounds in just two weeks….

The Physicist and the Dawn of the Double Helix

[These excerpts are from an article by Karl Sigmund in the 4 October 2019 issue of Science.]

      Three quarters of a century ago, Nobel laureate Erwin Schrodinger published What Is Life?, which described the forays of a “naive physicist” into biology and suggested that hereditary properties are encoded in an “aperiodic crystal.” A meme was born that changed the life sciences forever….

      What Is Lift? became one of the most important science books ever, not for its content (whose limitations were soon evident) but for its influence on a cohort of brilliant scientists. Almost all of the protagonists of the double helix saga acknowledged, at one time or another, the impact of Schrodinger’s book (the one possible exception being crystallographer Rosalind Franklin, who died before writing her memoirs)….Many of them—including Francis Crick, Maurice Wilkins, and Seymour Benzer—were physicists, but some were chemists (such as Erwin Chargaff and Gunter Stent) or physicians (such as Francois Jacob). Even a teenage bird watcher named James Watson became “polarized towards finding out the secret of the gene” after reading Schrodinger's booklet….

      Schrodinger’s prescient vision of genetic coding is one message in What Is Life?. Another is that cells create order from order….

      Six months after the discovery of the double helix, and a mere 10 years after the Dublin lectures, Francis Crick sent a letter to Schrodinger, acknowledging the impact of What Is Life? on both himself and Watson. Schrodinger did not reply. Even stranger, he never returned to biology….

Parched Peatlands Fuel Indonesia’s Blazes

[This excerpt is from an article by Dennis Normile in the 4 October 2019 Science.]

      Once again haze is suffocating Indonesia, but some scientists say it could have been worse. Acrid smoke from fires set to clear land for agriculture has sent scores to hospitals with respiratory problems and closed thousands of schools in Indonesia and neighboring Malaysia. At its thickest, in mid-September, more than 100 flights had to be canceled because of poor visibility. Although the government has tried to seed clouds for rain and dump water from the air, only the monsoon rains due later this month are likely to quench the fires.

      Yet countermeasures Indonesia has taken since the last major haze event, in 2015, have helped limit this year’s disaster. A new agency is restoring degraded peatlands, where agribusiness has drained and dried out meters-thick layers of waterlogged vegetation, making it vulnerable to ground fires that are almost impossible to stop. The government has also beefed up a moratorium on the conversion of prime forest land underlain by peat….But virtually all experts agree that more is needed, including stricter enforcement of a ban on setting fires.

      Small farmers in Indonesia have long practiced slash-and-burn agriculture, and in recent decades large corporations have industrialized the practice. They own long-term concessions to develop plantations within publicly owned forests, many in swampy landscapes rich in organic material. Concentrated in the coastal plains of Sumatra, Borneo, and Papua, these peat forests provide a habitat for rare species such as orangutans, leopards, Sumatran tigers, tapirs, white-winged ducks, and freshwater turtles. But in the 1980s, concession holders started to dig drainage canals through peatlands to float out logs and dry out the peat to plant dryland crops, especially oil palm and acacia trees for pulp and paper. Fires they set to clear the land can burn out of control.

      Peatlands play an outsize role in the hazes because dry underground peat deposits provide “an inexhaustible supply of fuel”….And because the very ground is burning, “the fires can’t be contained until the monsoon.” They release not just smoke, but vast quantities of greenhouse gases. Indonesian tropical peatlands, 36% of the world's total, hold an estimated 28.1 gigatons of carbon, according to a 2017 study—more than all the country’s upland forests.

      The conflagrations are paced by the weather. In 2015, an El Nino in the western Pacific Ocean combined with another irregularly recurring climatic phenomenon called the Indian Ocean dipole to make Indonesia’s typically dry summer even drier….Fires raged from late June until the end of October, burning 2.6 million hectares, an area half the size of Costa Rica. The haze affected countries as far away as Thailand and the Philippines….

      To remove the Incentive to set fires—as well as preserve Indonesia’s remaining rainforests—the government in 2018 decided not to grant new licenses for oil palm plantations, instead focusing on boosting yields from existing sites and lessening their environmental impact….And in August, Indonesia made permanent a temporary moratorium on converting primary forests and peatlands to agricultural use. The government has also promised stricter enforcement of laws that make concession holders responsible for fires in their holdings, regardless of whether they are deliberately set. Penalties can include criminal prosecution.

      Because the years since 2015 have been relatively wet, the measures had never really been tested—until this year. The Indian Ocean dipole again gave Indonesia an extremely dry summer….

Language and the Brain

[These excerpts are from an editorial by Lera Boroditsky in the 4 October 2019 issue of Science.]

      Languages—exquisitely structured, complex, and diverse—are a distinctively human gift, at the very heart of what it means to be human. As such, language makes for both a particularly important and difficult topic in neuroscience. A dominant early approach to the study of language was to treat it as a separate module or organ within the brain. However, much modern empirical work has demonstrated that language is integrated with, and in constant interplay with, an incredibly broad range of neural processes.

      Unlike other areas of neuroscience investigation (e.g., vision, motor action) that have relied heavily on invasive techniques with animal models, the study of language lacks any such model….

      At the same time, language is a powerful engine of human intellect and creativity, allowing for endless recombination of words to generate an infinite number of new structures and ideas out of “old” elements. Language plays a central role in the human brain, from how we process color to how we make moral judgments. It directs how we allocate visual attention, construe and remember events, categorize objects, encode smells and musical tones, stay oriented, reason about time, perform mental mathematics, make financial decisions, experience and express emotions, and on and on.

      Indeed, a growing body of research is documenting how experience with language radically restructures the brain. People who were deprived of access to language as children (e.g., deaf individuals without access to speakers of sign languages) show patterns of neural connectivity that are radically different from those with early language exposure and are cognitively different from peers who had early language access. The later in life that first exposure to language occurs, the more pronounced and cemented the consequences. Further, speakers of different languages develop different cognitive skills and predispositions, as shaped by the structures and patterns of their languages. Experience with languages in different modalities (e.g., spoken versus signed) also develops predictable differences in cognitive abilities outside the boundaries of language. For example, speakers of sign languages develop different visuospatial attention skills than those who only use spoken language. Exposure to written language also restructures the brain, even when acquired late in life. Even seemingly surface properties, such as writing direction (left-to-right or right-to-left), have profound consequences for how people attend to, imagine, and organize information.

      The normal human brain that is the subject of study in neuroscience is a “language” brain. It has come to be the way it is through a personal history of language use within an individual’s lifetime. It also actively and dynamically uses linguistic resources (the categories, constructions, and distinctions available in language) as it processes incoming information from across the senses.

      Put simply, one cannot understand the human brain without understanding the contributions of language, both in the moment ofthinking and as a formative force during earlier learning and experience. When we study language, we are getting a peek at the very essence of human nature. Languages—these deeply structured cultural objects that we inherit from prior generations—work alongside our biological inheritance to make human brains what they are.

Coming of Age in the Animal Kingdom

[These excerpts are from an article by Linda Wilbrecht in the 27 September 2019 issue of Science.]

      An enduring story plot finds a youth suddenly alone in the world, struggling to find shelter from the elements, safety from predators, food, and new friends. These struggles usually involve some tough lessons but ultimately lead to knowledge, a new identity, self-reliance, and maybe even love. In Wildhood, this theme comes to exhilarating life as evolutionary biologist Barbara Natterson-Horowitz and science writer Kathryn Bowers describe the challenges faced by adolescent animals.

      The book relates the coming-of-age stories of a king penguin named Ursula, a hyena named Shrink, a humpback whale named Salt, and a European wolf named Slavc—all adolescent animals and research subjects followed by field biologists. We meet Ursula as she leaves her parents for the first time and jumps daringly into the icy sea filled with hungry leopard seals. We watch Shrink, who has an unusual knack for social situations, rise in the stark hierarchy of hyenas. We observe Salt develop desire and navigate courtship and consent among “rowdy groups” of bull whales and follow Slave as he sets out on an epic journey across the Alps in winter.

      In addition to these four stories, the authors include smaller anecdotes and gleanings from observations of other wild animals and human youth, all members of the “horizontal tribe of adolescents.” On a single page, you might meet bald eagles, flying foxes, salamanders, and fruit flies. Collectively, the stories illustrate four competencies: how to stay safe, how to live with others, how to communicate sexually, and how to leave the nest and care for oneself.

      Learning to stay safe involves taking risks and getting close to danger. The first pages of the book introduce readers to a group of adolescent sea otters in California that swim in the “Triangle of Death,” where great white sharks lurk and there are few places to hide. In choosing to swim where no others dare, those that survive learn to identify and evade predators. Additional examples—from clueless farmed salmon to human teenagers at scary movies—emphasize the fact that some level of risk-seeking behavior may make individuals safer, more informed adults….

      Some animals, like some kids, never leave home. In the animal kingdom, this can be a rather good strategy. Male western bluebirds that stick around for the winter sometimes inherit their parents' territory, and there are red squirrel mothers who fill up caches for their young and then move out, leaving behind a proven territory for their lucky offspring.

      There are special considerations for social animals that live in groups. A parent wondering why their teenager is obsessed with status and social media will likely be interested to learn that “status is like gravity,” helping social creatures from chickens to hyenas to humans gain greater access to food, territory, and other resources. The authors point out that in the natural world, status assessments may be limited by space and season, but for modern youth, the internet may create status assessment overload.

      Wildhood’s chapters on sexual development call for more education on courtship, relationships, and consent and less focus on the sex act itself. They explain that moths, songbirds, and whales first must practice courtship rituals and need to learn to correctly read the cues made by others.

      …By laying out the adolescent experience of so many species in rich detail, the authors normalize and celebrate the beauty and complexity of our own species’s journey into the big wide world.

The Education of an Educator

[These excerpts are from an article by Roshini Ramachandran in the 27 September 2019 issue of Science.]

      …I also knew that the course had a reputation for doling out few A’s. This was a source of stress for premed students in particular, who feared that a low grade in organic chemistry would keep them from getting into medical school. I had no idea that my exam could elicit a full-blown panic attack, though….

      The following day, I was scheduled to lecture to the same class. I knew that I had to address what had happened during the midterm. I didn’t want to infringe on the student's privacy by mentioning her. So, I started by saying: “I want to take some time today to talk about something important. How many of you think that this is a weed-out course?” Half of my students raised their hands gingerly. “I’m sorry to hear that,” I continued. “I want you all to know that I do not consider any of you to be weeds; you all deserve to be here.”

      I flashed a slide of flowers in various shapes and hues—a stark contrast from the chemical structures I'd shown in past lectures. I smiled at my students and said: “I think of you as flowers—different flowers with different needs. You may not bloom at the same time, but you will bloom! You may not do well in a midterm exam, but you will learn from your mistakes and do better on the final exam. I believe this. I believe in you.”

      From that point on, my office hours were packed. Previously, only a few top-performing students had come, but the new batch included students who were struggling as well as those who were first-generation college attendees. Some asked about lecture topics and study strategies; others opened up about personal issues—family health problems, impostor syndrome, depression—that they’d been struggling with. I was amazed that a simple, frank discussion in lecture could make such a difference.

      We educators shouldn’t need a crisis to remind us of our students’ emotional needs. But it took a crisis to transform my approach to teaching. I now make a point of talking about mental health at the outset of every course, giving the students my “flower” speech and mentioning places where they can go for extra support. Before exams, I ask my students to use digital clickers to rate their current mental health and I share the results on-screen, which helps students realize that they're not alone in feeling stressed.

      Finally, I do my best to learn my students’ names. This may seem like a small thing, and it’s challenging in such a large class. But I’ve found that they feel valued—and are more likely to ask me for help—when I put in the effort to recognize them as unique individuals.

Minefield

[These excerpts are from an article by Warren Cornwall in the 27 September 2019 issue of Science.]

      …Bristol Bay consistently sees tens of millions of returning fish, year after year, making it one of the world’s most productive and lucrative salmon fisheries….A mining company wants to extract copper and gold from a massive ore deposit beneath headwaters of two of Bristol Bay’s main salmon rivers. The Pebble Mine could become one of the world's biggest mineral producers, with an open pit nearly as deep as the Grand Canyon and vast infrastructure and waste piles that would stretch for kilometers.

      Opponents of the project, including Native Alaskan, fishing, and environmental groups, have long argued that the mine’s short-term economic benefits would pale in comparison with the long-term risks to Bristol Bay’s salmon runs, including toxic runoff and habitat destruction. Critics have seized on Schindler's science to help make their case, and in 2014 the findings helped persuade then-President Barack Obama’s administration to move to block the mine. But this year President Donald Trump’s administration signaled it might allow the project as part of its efforts to encourage development.

      …Over the past 4 decades, an average of nearly 40 million salmon have returned to the bay each year. (By comparison, it's a good year when 3.5 million fish return to the Columbia River, the largest salmon river in the lower 48 states.) Most are sockeye, which spend their first year or two in freshwater and then head out to the North Pacific Ocean for 1 to 3 years before returning to reproduce. The deluge of fish draws more than 2000 commercial fishing boats, fueling a salmon economy worth about $300 million a year. Bristol Bay accounts for nearly half of all sockeye caught in the world….

      If Northern Dynasty Minerals, based in Vancouver, Canada, has its way, a piece of the landscape will be transformed. Several versions of the Pebble Mine have emerged in company proposals and studies done by the Environmental Protection Agency (EPA) in Washington, D.C. Under the most expansive scenarios, it would become the world’s biggest gold producer and one of the top 10 copper mines, yielding up to 24 million tons of copper and 1400 tons of gold over its lifetime. An open pit covering 18 square kilometers would be the largest in North America. Infrastructure would include 195 kilometers of road and humanmade lakes full of toxic mine wastes covering an area nearly the size of New York City’s Manhattan island. It could employ more than 1000 people during regular operations and bring in revenues of $300 billion to $500 billion, according to an EPA study.

      Even that massive operation would be dwarfed by the immense Alaskan landscape. Constructing a smaller version of the mine, for example, would touch on streams draining less than 1% of the land surrounding Bristol Bay, according to the U.S. Army Corps of Engineers.

      But mine opponents fear that once roads and other infrastructure are built, the mine could expand and surrounding mining claims could become viable. And Schindler notes that even a single mine could have big impacts. It would straddle two of Bristol Bay’s watersheds. One drains into Lake IIiamna, Alaska’s biggest, which has produced about one-fifth of the bay’s sockeye salmon over the past 2 decades. The other feeds the Nushagak River, which has produced an average of 6.5% of sockeye populations….

      In 2014, Obama’s EPA took the unusual step of announcing it planned to veto Northern Dynasty's expected application for a federal permit needed to fill wetlands and streams, effectively killing the project. The agency pointed to a host of hazards: tens of kilometers of streams and tributaries destroyed, disruption of water flows, and the risk of stream pollution from copper—a potent aquatic poison—stirred up by mining. If a tailings dam failed in the earthquake-prone region, contaminated waste could pour down a nearby river. Even a smaller version of the mine, the agency declared, “jeopardizes the long-term health and sustainability of the Bristol Bay ecosystem.”

      The portfolio effect underpinned those concerns. Though the mine would touch only a small percentage of the overall system, and even a catastrophic failure wouldn’t reach most watersheds, agency scientists feared that losing even some pieces could undermine the whole system. What would happen in years when salmon populations in other streams went bust, and damaged streams weren't there to take Lup the slack?

      …Trump’s election, however, as well as the later election of a pro-mining Alaskan governor, has given the Pebble Mine new life. In 2017, the company proposed a mine with a smaller footprint and more environmental safeguards, which it says would address EPA's concerns. For example, the company says that after 2 decades of mining it would dump the tailings into the pit and cover them with water, eliminating the need for storage ponds.

      Several federal agencies, now led by Trump appointees, have greeted the new plan more warmly. In February; the Army Corps, which controls federal wetlands permits, issued a draft environmental impact statement, finding the project would cause no population-level damage to salmon. In July, EPA withdrew its earlier veto proposal, saying its previous conclusion was outdated. Trump administration officials have suggested they hope to issue a final decision on the mine’s wetland permits by mid-2020. Whatever the timeline, any decision is certain to be challenged in court.

      …The company’s newest proposal calls for mining roughly 15% of the ore deposit and not reaching the richest veins….many critics, including Schindler, suspect the current plan is just a first phase, downsized to pass regulatory muster while opening the door to a much bigger future mine—with much greater environmental impacts.

      Federal wildlife agencies have expressed similar concerns. The National Marine Fisheries Service and the Department of the Interior (DOI) have warned that the Army Corps has largely ignored the possibility of a bigger mine and understated or failed to consider risks to salmon. DOI officials wrote that the draft study was “so inadequate that it precludes meaningful analysis….”

Warming Transforms the Oceans and Poles

[These excerpts are from an article by Paul Voosen in the 27 September 2019 issue of Science.]

      Water, liquid and frozen, occupies most of Earth’s surface, with oceans covering two-thirds of it and ice another 10th. All is being transformed by climate change, posing greater threats to life and human society than scientists had realized, according to a special assessment of climate science focused on oceans and ice released this week by the United Nations.

      The report, from the Intergovernmental Panel on Climate Change (IPCC), comes during a week when the world is fixated on what many now call the climate crisis. The planet has already warmed 1°C since preindustrial times, and July was the hottest month in the modern record….

      …the watery parts of the planet are already entering a new state. After 0.2 meters of sea level rise since the late 1800s, some coastal cities flood routinely during high tides. With the Arctic warming at double the global rate, sea ice is in rapid decline, causing severe disruption to Indigenous communities and wildlife. Permafrost is thawing, undermining infrastructure and releasing uncertain amounts of buried carbon. The ocean is warming at all depths, and heat waves increasingly strike its inhabitants….

      Compared with the last U.N. climate report, in 2014, the new assessment paints a grimmer picture of the future. By 2100, within the lifetime of those striking children, global sea level would likely rise by up to 1.1 meters if greenhouse gas emissions continue unabated; the last IPCC report had set the upper limit at 0.98 meters. Even with steep cuts in fossil fuel burning, the oceans will rise between 0.29 and 0.59 meters, the report adds….

      Without action, rare, catastrophic storm surges will become common within 30 years….Rising waters pose a particular threat to small island nations near the equator, where storms are rare and sea level typically varies little, allowing infrastructure to be built close to the ocean. There are also examples of resilience: Shanghai, China, for example, pumped water back into its underground aquifers to counteract subsidence that had made the city more vulnerable to sea level rise—a challenge also facing many other coastal cities.

      The ocean’s structure and composition are changing in less obvious ways….Over the past 15 years, an array of 4000 autonomous floats has documented steady, continuous warming extending to the ocean depths. This warming makes surface waters less dense and more buoyant and reduces mixing with deeper layers. Fewer nutrients well up from the deep, and less oxygen mixes downward….

      Across the Arctic, the thawing permafrost could amplify climate change by releasing carbon it has held for millennia. But when the impact of those extra emissions will be felt is unclear. Warmer temperatures are causing the Arctic to become greener, and the increasingly luxuriant plants are capturing extra carbon and storing some of it in the soil. At some point, however, the carbon released is likely to overwhelm the carbon absorbed….

      Like all IPCC reports, this week’s assessment reflects only science submitted for publication, which means it is already out of date….

      Perhaps the biggest struggle for IPCC scientists has been assessing the speed of future sea level rise, which hinges largely on the fate of the West Antarctic Ice Sheet. The odds are low that the ice sheet will collapse this century, which would eventually drive meters of extra sea level rise. But in recent years, several of its vital buttressing glaciers have slid toward the sea, and an international team is now studying its most at-risk glacier, Thwaites. Scientists continue to debate whether an unstoppable collapse has already begun….

      It’s one more reason for the world to make big cuts in carbon emissions, right away….

Fly Less to Convey Urgency

[These excerpts are from an editorial by Peter Kalmus in the 27 September 2019 issue of Science.]

      Last week, just days before the United Nations Climate Summit in New York, students across the globe protested in response to inaction over the greatest threat to humanity. Climate breakdown exists on a continuum of harm—it will get worse the hotter the planet gets. Limiting the catastrophe requires an effort at all scales of society.

      Climate breakdown can't be fully understood without data, sophisticated analysis, and models. These tools of science are needed, for example, to formally attribute disasters such as hurricanes, floods, and wildfires to human-caused global heating, or to understand what humanity will face on a hotter planet. It is understandably difficult for the public and policy-makers to directly consult the peer-reviewed literature and respond appropriately. This suggests that scientists have an ethical responsibility to alert the public.

      …Now, the climate crisis is so severe that many scientists are looking for other ways to persuade society to accelerate climate action.

      …When a scientist speaks only in the language of facts, the message gets through mostly to other scientists. Those without scientific training tend to look for emotional cues and reasons to trust scientists; without them, they may underestimate a scientist’s level of concern. Scientists can bridge this gap by also speaking from the perspective of a concerned citizen and by taking personal actions that the public can relate to….

      Hour for hour, it’s hard to find a better way to heat the planet. Flying coach burns 0.2 to 0.3 kg of carbon dioxide (CO2) worth of jet fuel per passenger mile, roughly equivalent to driving (alone) a gasoline car that gets 40 to 50 miles per gallon. Add three passengers, and the car emissions go down to 0.06 kg of CO2 per passenger mile. Short-term radiative forcing from ozone production, contrails, and cirrus cloud formation further increases the climate impact of planes. Although aviation accounts for only 2% of global carbon emissions, flying less could be a powerful lever for cultural shift. In some sectors, including academia, flying reflects freedom and even success. If scientists fly less, it could communicate climate urgency more effectively.

      Frequent flying is often justified by carbon offsets or by invoking the possibility of future carbon-free flight. However, battery energy densities are still an order of magnitude too low to support long-distance fights, and there is not enough biofuel to support aviation at the scale needed. Offset companies cannot guarantee that offsetting practices will permanently sequester an equivalent amount of carbon and even if they could, people should be embracing those practices anyway, without negating them with flight emissions.

      Not all scientists can eliminate flying, but it’s time for the scientific community to find creative alternatives to the fly-in meeting. These could include regional meeting hubs connected by remote technology, asynchronous on-line-only conferences, or virtual reality conferences. Such efforts could lead to co-benefits such as smaller, specialized meetings and increased participation by students and low-income nations. Flying is tied to the scientific profession and flying less is an action that can be taken as a community, amplifying individual actions through the authority of its institutions and professional societies and sending a clear message of climate urgency to the public.

Low-Carbon Air Travel Is Coming

[This excerpt is from an article by Wade Roush in the October 2019 issue of Scientific American.]

      …An online calculator showed that the flights I take every year put a yikes-inducing 15 metric tons of carbon into the atmosphere—equivalent to the overall annual carbon emissions of three average earthlings. So I signed up with a company called terrapass to buy offsets for 12 tons of carbon a year, at about $10 per month. Terrapass uses that money to do commendable things such as capturing methane from landfills, building wind farms and preserving carbon-sequestering forests.

      I’m not under the illusion that these projects cleanse my sins as an air traveler. At best., they simply prevent the release of an equal quantity of greenhouse gases down the road. The offsets do help me and other consumers feel less guilty about flying—which is probably why airlines such as United and Delta now offer them as part of the booking process. And on a larger scale, there’s evidence that offsets function as a kind of self-imposed carbon tax, encouraging people who buy them to keep their own energy use in check. But the reality is that voluntary offsets will never come close to matching aviation emissions, which account for 2 percent of overall human-induced carbon emissions.

      For one thing, any benefit from offsets is likely to be overwhelmed by growing demand for air travel. According to a recent report from Airbus, about 4.0 percent of the world population is now middle class, and by 2037 this group will have mushroomed to more than 50 percent, or some five billion people—“all in the pool of regular or potential new” passengers.

      And buying an offset isn’t a guarantee that your flight emissions will actually be, you know, offset, since it’s difficult to prove that carbon-avoidance projects wouldn’t have happened anyway or that the neutralized carbon will never be released in the future….

      Regardless of their relation to consumer trends, offsets aren’t a solution to the underlying physics problem in aviation, which is that today’s long-haul passenger jets can’t take off without burning a high-energy-content fuel such as kerosene. That’s why OPEC is confident that worldwide demand for jet fuel will reach nine million barrels a day by 2040, up from 6.3 million in 2017.

      Short of drastic rationing of air travel, the only long-term solution for aviation’s carbon woes is electrification. Biofuels from feedstocks such as sugarcane, algae and household garbage, which burn more cleanly than fossil fuels, could help in the short run—United has been mixing them into traditional jet fuel since 2016. But the real hope lies in projects such as E-Fan X, a test plane from Airbus, Rolls-Royce and Siemens in which one of the four gas-powered turbofans is replaced by an electric motor. The partners see the project as a step toward meeting the European Union's ambitious “Flightpath 2050” goal of reducing aviation’s carbon dioxide emissions by 75 percent by 2050.

      Start-ups are getting into the game, too: Seattle's Zunum Aero, backed by Boeing and JetBlue, is designing a regional jet with batteries in the wings and fans powered with a “hybrid to electric” power train. To be light enough for flight, aviation batteries will need a specific energy—a measure of how much power a battery contains for its weight—far beyond that of today’s lithium-ion battery packs. So, for the time being, Zunum’s power train will run partly on jet fuel.

      The improvements in batteries and motors needed to fully electrify the skies could take “the next few decades,” Zunum co-founder B. Matthew Knapp acknowledged in a recent Nature Sustainability op-ed. Meanwhile buying offsets is a substitute that both feels good and does good. Just don't assume that it will keep our climate-spoiling travel habits aloft forever.

Venomous Secrets

[This excerpt is from an article by Rachel Crowell in the October 2019 issue of Scientific American.]

      We rarely think of scorpions as beneficial. But researchers have isolated two new compounds in the arachnids’ venom that show promise for treating staph infections and drug-resistant tuberculosis.

      Scorpion venom is beyond expensive: harvesting a milliliter would cost about $10,300….He estimates that “milking” venom from one scorpion can yield only a few thousandths of a milliliter at a time at most, and it takes two or more weeks for an individual’s supplies to replenish. The substance can still be worth studying, however. Some of its constituent compounds have intriguing medicinal properties and can be synthesized more cheaply in the laboratory.

      Researchers…milked scorpions of the eastern Mexican species Diplocentrus melici, whose venom had never been studied before. They separated its components and tested some on Staphylococcus aureus, Escherichia coli and Mycobacterium tuberculosis bacteria. Two of these components—one of which happens to be red when isolated and the other blue—killed staph and TB microorganisms, suggesting their potential as antibiotics.

      The researchers sent small samples of the isolated compounds to…Stanford to determine the substances’ compositions and molecular structures. The group then chemically synthesized the compounds….

      There pathologists tested the synthesized substances in mice infected with tuberculosis and on human tissue samples hosting staph bacteria. The red compound proved more effective at killing staph, and the blue one worked better on TB—including a drug-resistant strain—without damaging the lining of the mice’s lungs.

      …the study’s approach seems promising. But she cautions that the compounds still need to be tested in larger animals—and they could also be challenging to synthesize on the scales required for testing in humans.

Going the Distance

[This excerpt is from an article by Jennifer Leman in the October 2019 issue of Scientific American.]

      After poison frog tadpoles hatch from their eggs in the leaf litter, they wriggle onto the backs of their patiently waiting fathers, who piggyback them to water. Scientists studying the candy-colored amphibians, sometimes called poison dart frogs, in the Amazon rain forest recently discovered that frog dads often skip close-by ponds in favor of something more distant—a move that expends precious ener-gy. Sometimes they traveled as far as 400 meters….

      Three-striped poison frogs traveled farthest, traversing an average distance of roughly 215 meters—when the nearest available pool was on average only 52 meters away from their home territory. Dyeing dart frogs traveled approximately 39 meters on average, hopping past ponds an average distance of 19 meters away. Two frogs even left the forest's shelter to deposit their tadpoles in flooded pastures.

      Despite the energy cost and higher risk of meeting predators, dropping young tadpoles in faraway pools may offer evolutionary benefits such as decreased risk of inbreeding and less competition for resources….But it is difficult to say what exactly motivates the frogs themselves to go farther….

Disappearing Bodies

[This excerpt is from an article by Bahar Gholipour in the October 2019 issue of Scientific American.]

      In 1231 Frederick II, the Holy Roman Emperor who ruled over much of Europe, issued a decree requiring schools that trained doctors to hold a human body dissection once every fiveyears. It was a slow debut for what would become a cornerstone of medical education. During the Renaissance, cadaver dissections helped scientists and artists gain a hands-on understanding of human anatomy. Today they are an essential experience for first-year medical students, a time-honored initiation into the secrets of our flesh.

      Now, nearly a millennium after its measured introduction, cadaver dissection may have begun an equally slow exit. This year a few U.S. medical schools will offer their anatomy curriculum without any cadavers. Instead their students will probe the human body using three-dimensional renderings in virtual reality, combined with physical replicas of the organs and real patient medical images such as ultrasound and CT scans.

      The program developers hope technology can improve on some of the limitations of traditional approaches. It takes a long time to dissect cadavers, and some body parts are so inaccessible that they may be destroyed in the process. Plus, the textures and colors of an embalmed cadaver’s organs do not match those of a living body, and donated bodies tend to be old and diseased….

      …When he tried to access organs in living patients, looking at imaging results or footage from tiny inserted cameras, he found the inside of human bodies did not match what he had seen in cadavers. “They’re totally different,” Young says. “The embalmed cadaver has a very flat, cornpressed organ presentation. The colors are not the vibrant colors of a living human.” The difference can distract from learning….

      Virtual anatomy tools, in contrast, provide a more faithful view of living organs, helping students form a foundational understanding of the body’s structures….By donning VR headsets or augmented-reality goggles, which show digital imagery super-imposed on the real world, students can examine an organ from all angles. They can connect structure with function by watching a beating heart or moving joints. They can also select views that add other organs or the entire circulatory and nervous systems to better see relations among structures….

      Adopting high-tech alternatives makes sense for brand-new medical programs that have neither the tradition nor the facilities for cadaver dissection, but even some existing ones are adopting digital tools to supplement their anatomy courses….

      Besides the educational advantages, going cadaverless is an economic decision for new programs. It costs several million dollars to build a cadaver laboratory, which requires a lot of space, as well as safety measures that meet legal regulations. And although cadavers are donated, medical schools still pay for preparation, maintenance and, eventually, burial. These costs are an even bigger challenge for schools in less wealthy nations….

      Cadaverless anatomy education has its drawbacks. It may be hard to develop a perception of depth in a virtual body, and students will miss out on seeing bodies’ natural anatomical variations…. Students may also lose the emotional, even philosophical impact of working with a cadaver, commonly seen as a doctor’s first patient….

      Another open question is whether students learn as well using the digital tools. Educators’ studies are probing whether replacing old techniques with new technology will actually improve, and not harm, the quality of their students’ education. Their results, if positive, may encourage more schools to convert….

Closing the Skills Gap

[This excerpt is from an article by Rick Lazio and Harold Ford in the October 2019 issue of Scientific American.]

      …Given these statistics and the rapid adoption of new technology, it is clear that STEM skills will be critical in the new tech economy. If left unaddressed, the shortage of STEM workers will have long-term and extremely consequential ramifications such as stagnated economic growth. This situation leaves our country at considerable risk of losing high-paying jobs to other nations.

      …The U.S. is falling behind other countries in achievement in STEM areas for a variety of reasons, including a lack of consistent exposure to the relevant subjects for young students—particularly minority students. Although both the Obama and Trump administrations emphasized the importance of STEM education, with the U.S. Department of Education investing $279 million in STEM discretionary grant funds in 2018, more can be done to make the system consistent for all of America's K-12 students.

      In 2015, according to the Pew Research Center, the U.S. placed 38th in math and 24th in science out of 71 participating nations in the Program for International Student Assessment (PISA), one of the largest tests to measure reading, math and science literacy. Also, the World Economic Forum reported that in 2013, 40 percent of Chinese graduates completed a degree in STEM—more than double the percentage of Americans. These numbers clearly point to a disturbing trend in our country’s ability to funnel technical labor into the workforce and remain competitive on an international scale.

      So how do we reverse this alarming trend? First, we must make STEM curricula central to primary and secondary school standards and encourage students to pursue STEM careers. Second, we must rethink our approach to education. Learning should be a lifelong endeavor, not just a K-12 priority. Businesses laying the groundwork for disruptive operational change via automation, Al and other means must also prepare to retrain their workers and give them the technical skills needed for the company’s next generation of jobs.

      Finally, immigration reform can ensure that those who enter the U.S. for a STEM education receive incentives to stay and contribute to our economy….

Cleaning up Plastic Pollution in Africa

[These excerpts are from an article by Bilikiss Adebiyi-Abiola, Solomon Assefa, Kareem Sheikhand Jeannette M. Garcia in the 20 September 2019 issue of Science.]

      …Over 416 billion plastic bags per month are used globally. In Africa, they litter roads, rivers, boreholes, and sewage systems. In many African countries, increasing plastic pollution has motivated policy-makers to enact legislation to protect the environment from further contamination. Currently, Africa has the highest percentage of countries (-46%) with plastic bans. For example, in 2008, Rwanda took the global lead in banning nonbiodegradable polyethylene bags. The law prohibits the manufacture, use, import, and sale of nonbiodegradable bags that fall outside its sustainability criteria, and violations are punishable by high fines or jail time. It is strictly enforced at airports and other port entries by agents from the Rwanda Environment Management Authority. Tax incentives in Rwanda are motivating plastic bag manufacturers to consider recycling as a business opportunity. The policy has led to local production of sustainable bags made from local materials, alleviating fears about negative impact on small businesses, jobs, and foreign direct investment.

      Some African countries are following Rwanda’s lead, albeit with less effective law enforcement. Tanzania is in the second phase of its plastic ban, and Kenya is following a gradual path by taxing plastic bags. Although Kenya implemented a plastic bag ban in 2017, punishable with fines and jail time, enforcement has been difficult. The tax has decreased consumer demand for single-use plastic shopping bags and increased the use of reusable alternatives. Kenya also is incentivizing community-led collection that is turning plastics into mattresses and eco-friendly asphalt, bricks, fencing posts, school bags, and shoes….

      Many of the programs in Africa that limit the production of new, nonbiodegradable plastics have occurred in the last 4 years. Thus, there are few data about the efficacy of these programs and technological efforts to tackle plastic waste, but the engagement and public responses are encouraging. Although efforts to limit plastic use may reduce the introduction of new plastics into the environment, the need to address plastic pollution already present in Africa still remains.

      Plastics pollution prevention in Africa is tightly coupled to the economics of recycling. Globally, about 90% of all waste is dumped or burned in low-income countries. In high-income regions, waste management is more regulated and recycling rates are higher….In African urban areas where formal waste collection and sorting infrastructure are available (primarily in city centers), new technologies for vehicle-based waste collection can improve collection efficiency. In one example, about 2500 metric tons of waste is generated daily in Nairobi, Kenya, but only -50% of the garbage is collected….

      The African population is expected to grow to 2.5 billion by 2050. Its most populous city, Lagos, Nigeria, is projected to grow to 32.6 million by that time. In 2014, 12,000 tons of waste was generated daily by Lagos citizens, 15% of which was plastic. The overburdened Lagos municipality collected only about 40% of this total generated waste. Once collected, waste is taken to dumpsites and plastics are recycled manually in the budding recycling sector. Despite health and safety risks involved in this work, informal and formal waste reclaimers are a key component of waste management, not only in Lagos but across Africa. For example, waste workers are responsible for recycling 80 to 90% of the plastic packaging that is recycled in South Africa.

      Plastic recycling in Africa has focused on commodity plastics and is mainly centered on first-level processing (such as baling and shredding). Such processed plastic is then sold and exported to Asia, where it is down-cycled to products such as pillow stuffing. Although this extends the lifetime of materials, the process creates downcycled products that can no longer be recycled….

      Collecting enough plastic waste to feed recycling plants is a continuous struggle anywhere in Africa. Formal collection infrastructure is still being developed across municipalities. The absence of policies to promote plastic recycling at-scale, coupled with limited road networks for general waste collection, little public awareness of plastic recycling, and an unstable global plastic recycling market, has stunted the adoption of recycling in several African cities….

      The rapid adoption of information technologies at various points along the plastic waste recycling chain can facilitate the realization of a closed-loop plastic waste ecosystem. Regional factors, such as government regulations and consumer motivation to improve African quality of life, play a critical role in the adoption of technologies to tackle plastic pollution in an environment that otherwise lacks a plastics recycling framework….

Renewable Bonds

[These excerpts are from an article by Robert F. Service in the 20 September 2019 issue of Science.]

      Black, gooey, greasy oil is the starting material for more than just transportation fuel. It's also the source of dozens of petrochemicals that companies transform into versatile and valued materials for modem life: gleaming paints, tough and moldable plastics, pesticides, and detergents. Industrial processes produce something like beauty out of the ooze. By breaking the hydrocarbons in oil and natural gas into simpler compounds and then assembling those building blocks, scientists long ago learned to construct molecules of exquisite complexity.

      Fossil fuels aren’t just the feedstock for those reactions; they also provide the heat and pressure that drive them. As a result, industrial chemistry’s use of petroleum accounts for 14% of all greenhouse gas emissions. Now, growing numbers of scientists and, more important, companies think the same final compounds could be made by harnessing renewable energy instead of digging up and rearranging hydrocarbons and spewing waste carbon dioxide (CO2) into the air. First, renewable electricity would split abundant molecules such as CO2, water, oxygen (O2), and nitrogen into reactive fragments. Then, more renewable electricity would help stitch those chemical pieces together to create the products that modern society relies on and is unlikely to give up….

      Chemists in academia, at startups, and even at industrial giants are testing processes—even prototype plants—that use solar and wind energy, plus air and water, as feedstocks….The company, located in a low-slung office park in Berkeley, has designed a washing machine-size device that uses electricity to i.,, v convert water and CO2 from the air into fuels and other molecules….

      Changing the lifeblood of industrial chemistry from fossil fuels to renewable electricity “will not happen in 1 to 2 years,” says Maximilian Fleischer, chief expert in energy technology at Siemens. Renewable energy is still too scarce and intermittent for now However, he adds, “It’s a general trend that is accepted by everybody” in the chemical industry.

      A sharp rise in supplies of solar, wind, and other forms of renewable electricity lies behind the trend. In 2018, the world surpassed 1 terawatt (TW) of installed solar and wind capacity. The second TW is expected by mid-2023, at just half the cost of the first, and the pace is likely to accelerate. One recent analysis suggests lower prices for renewable generation could prompt the development of 30 to 70 1W of solar energy capacity alone by 2050, enough to cover a majority of global energy needs….According to the National Renewable Energy Laboratory, the cost of utility-scale solar power should drop by 50% by 2050 and the cost of wind power by 30%.

      That surge in renewables has already led to brief periods when electricity supplies exceed demand, such as midday in sunny Southern California. The result is dramatic price drops. At times, utilities even pay customers to take electricity so that excess supply doesn’t melt transmission lines….

      But even if the heat comes from electricity reactions such as those that generate fuel from methane still emit waste CO2. Chemists want to go further, harnessing electrons not just as a source of heat, but as a direct input to the reactions. Industrial chemists already use electricity to smelt aluminum from bauxite ore and generate chlorine from salt—electron-adding reactions for which electrically driven chemistry is ideally suited. But as with H2, most commodity chemicals are made from fossil fuels, transformed with heat and pressure generated by more fossil fuels.

      Giving up those fuels doesn’t involve chemical magic. Key industrial chemicals such as carbon monoxide (CO) and ethylene can already be made by adding electrons to abundant starting materials such as CO2 and water, if efficiency is no object. The trick is to do so economically.

      That process requires a cheap source of renewable electricity….They found that electrosynthesis would be competitive for producing chemical staples such as CO, H2, ethanol, and ethylene if electricity cost 4 cents per kilowatt hour (kWh) or less—and if the conversion of electrical energy to energy stored in chemical bonds was at least 60% efficient.

      If electricity’s cost fell further, more compounds would be within reach….an electricity price of 2 cents/ kWh, synthesizing formic acid, ethylene glycol, and propanol would all be feasible….

      Kammen notes that several utility-scale solar and wind projects already meet one benchmark, delivering power at or below 4 cents/kWh, and the cost of renewables continues to decline….But reaching 60% conversion efficiency of electrical to chemical energy is a bigger challenge, and that’s where researchers are focusing their efforts.

      The simplest processes, those that make H2 and CO, are already reaching that second benchmark….

      …Last month, in Dresden, Germany, a company called Sunfire completed a test run of a high-temperature electrolysis reactor, known as a solid-oxide fuel cell, that promises even higher efficiency than PEM electrolyzers….Because the plant works at high temperatures, the water- and CO2-splitting reactions convert electrical energy to chemical bonds at nearly 80% efficiency, the company says….

      But as chemists develop new reactors and find ever-more-charmed combinations of catalysts—and as renewable energy continues to surge—the plants that churn out chemical staples will inevitably become more like the green variety, fully sustained by sun, air, and water.

400 Years and (Re)counting

[This editorial by Shirley M. Malcolm is in the 20 September 2019 issue of Science.]

      Over centuries of slavery in America, systematic structures were erected to present enslaved people as “the other”—a race apart and less than human—as a way to justify the institution and forestall discussions of its inhumanity and the moral imperative to dismantle it. These efforts included invoking science, as objective arbiter, in support of these viewpoints. Some theories of human origins, for example, espoused by great names of science, reflected attempts to bolster constructs of racial inferiority rather than to advance science. But they did their damage, and we live with their fallout even today. How many of the current challenges in diversifying science are part of this legacy: lack of investment in education; belief in innate capacity to do science (or not); exclusionary teaching practices; tolerance of classroom microaggressions; implicit bias in hiring, and in assessing and valuing work?

      This year marks the 400th anniversary of slavery in America, provoking scholarly retrospectives that have considered how central a role the concept of race has played in the course of human affairs, including in science. The ground that has been stirred offers an opportunity for soul searching and reflection, not only about science’s past but perhaps, more importantly, about its present and future. Articles have appeared, including in Science, revealing some of the scientific and medical advances associated with slavery, such as the natural history collections derived from the transatlantic slave trade where Africans were shipped to the Americas as enslaved people whose labors became a driving force of the economies of the European colonies, or the cruel experimentation on enslaved women in the history of gynecology.

      It is difficult to tell these stories or to read them, especially for those who are both descendants of these enslaved people and members of the science community. The marginalization continues today, long after the legal end of the institution. Outcomes manifest themselves as statistics documenting inequality and limited opportunity within and beyond the United States, such that, in the United Kingdom in 2018, blacks and other minorities comprised less than 1% of professors in higher education institutions.

      But the lens of science has also provided a powerful tool to help reframe the narrative of exclusion: race as social construct rather than biological reality; stereotype threat as self-fulfilling and reversible; lack of opportunity rather than lack of capacity. Sadly, the damage continues. How much of this legacy is represented (through the inherited trauma of epigenetic changes) in health disparities—poor disease outcomes; differential maternal and infant mortality for blacks and whites, independent of socioeconomic levels—or in wealth and income inequality? It is time to use scholarship to uncover the deeply rooted structures that science helped reinforce.

      Even while acknowledging blanket complicity, beyond science there is a powerful social infrastructure in laws and tolerance of behaviors that holds inequalities in place, and possibly more on the horizon such as artificial intelligence which, as a tool that relies on historical information, promises to deliver old discriminatory wine in new algorithmic bottles, cloaked in the black boxes of proprietary models.

      Continued inequality should not be an inevitable legacy of America’s past. Diverse perspectives and convergent scholarship can be applied to build an understanding from the history of biological and political theories, and from the social and cultural traditions that fuel today's system of inequality. Even if the political will should arise to take on the grand challenge of creating a system of opportunity for all, different institutional structures would be needed to begin the hard work: diverse participants, perspectives, fields, and practices; un-siloed, solution-focused, nonpartisan discussions; and governance by a search for truth and reconciliation. The United States needs a map that points the way to unpacking and dismantling the infrastructure of social inequality that was unleashed when slavers docked in Virginia 400 years ago.

Why We Trust Lies

[These excerpts are from an article by Cailin O’Conner and James Owen Weatherall in the September 2019 issue of Scientifi American.]

      In the mid-1800s a caterpillar the size of a human finger began spreading across the northeastern U.S. This appearance of the tomato hornworm was followed by terrifying reports of fatal poisonings and aggressive behavior toward people. In July 1869 newspapers across the region posted warnings about the insect, reporting that a girl in Red Creek, N.Y., had been “thrown into spasms, which ended in death” after a run-in with the creature. That fall the Syracuse Standard printed an account from one Dr. Fuller, who had collected a particularly enormous specimen. The physician warned that the caterpillar was “as poisonous as a rattlesnake” and said he knew of three deaths linked to its venom.

      Although the hornworm is a voracious eater that can strip a tomato plant in a matter of days, it is, in fact, harmless to humans. Entomologists had known the insect to be innocuous for decades when Fuller published his dramatic account, and his claims were widely mocked by experts. So why did the rumors persist even though the truth was readily available? People are social learners. We develop most of our beliefs from the testimony of trusted others such as our teachers, parents and friends. This social transmission of knowledge is at the heart of culture and science. But as the tomato hornworm story shows us, our ability has a gaping vulnerability: sometimes the ideas we spread are wrong.

      Over the past five years the ways in which the social transmission of knowledge can fail us have come into sharp focus. Misinformation shared on social media Web sites has fueled an epidemic of false belief, with widespread misconceptions concerning topics ranging from the prevalence of voter fraud, to whether the Sandy Hook school shooting was staged, to whether vaccines are safe. The same basic mechanisms that spread fear about the tomato hornworm have now intensified—and, in some cases, led to—a profound public mistrust of basic societal institutions. One consequence is the largest measles outbreak in a generation.

      “Misinformation” may seem like a misnomer here. After all, many of today’s most damaging false beliefs are initially driven by acts of propaganda and disinformation, which are deliberately deceptive and intended to cause harm. But part of what makes propaganda and disinformation so effective in an age of social media is the fact that people who are exposed to it share it widely among friends and peers who trust them, with no intention of misleading anyone. Social media transforms disinformation into misinformation….

      But even this group benefit does not guarantee that agents learn the truth. Real scientific evidence is probabilistic, of course. For example, some nonsmokers get lung cancer, and some smokers do not get lung cancer. This means that some studies of smokers will find no connection to cancer. Relatedly, although there is no actual statistical link between vaccines and autism, some vaccinated children will be autistic. Thus, some parents observe their children developing symptoms of autism after receiving vaccinations. Strings of misleading evidence of this kind can be enough to steer an entire community wrong….

      Yet the net result is that anti-vaxxers do not learn from the very people who are collecting the best evidence on the subject. In versions of the model where individuals do not trust evidence from those who hold very different beliefs, we find communities polarize, and those with poor beliefs fail to learn better ones.

      Conformism, meanwhile, is a preference to act in the same way as others in one’s community. The urge to conform is a profound part of the human psyche and one that can lead us to take actions we know to be harmful. When we add conformism to the model, what we see is the emergence of cliques of agents who hold false beliefs. The reason is that agents connected to the outside world do not pass along information that conflicts with their group's beliefs, meaning that many members of the group never learn the truth.

      Conformity can help explain why vaccine skeptics tend to cluster in certain communities….

      A classic example comes from the tobacco industry, which developed new techniques in the 1950s to fight the growing consensus that smoking kills. During the 19508 and 1960s the Tobacco Institute published a bimonthly newsletter called “Tobacco and Health” that reported only scientific research suggesting tobacco was not harmful or research that emphasized uncertainty regarding the health effects of tobacco.

      The pamphlets employ what we have called selective sharing. This approach involves taking real, independent scientific research and curating it, by presenting only the evidence that favors a preferred position. Using variants on the models described earlier, we have argued that selective sharing can be shockingly effective at shaping what an audience of nonscientists comes to believe about scientific matters of fact. In other words, motivated actors can use seeds of truth to create an impression of uncertainty or even convince people of false claims….

      Worse, propagandists are constantly developing ever more sophisticated methods for manipulating public belief. Over the past several years we have seen purveyors of disinformation roll out new ways of creating the impression—especially through social media conduits such as Twitter hots and paid trolls and, most recently, by hacking or copying your friends’ accounts that certain false beliefs are widely held, including by I your friends and others with whom you identify….

      The way to decide a question of scientific fact—are vaccines safe and effective?—is not to ask a community of nonexperts to vote on it, especially when they are subject to misinformation campaigns. What we need is a system that not only respects the processes and institutions of sound science as the best way we have of learning the truth about the world but also respects core democratic values that would preclude a single group, such as scientists, dictating policy….

Truth, Lies & Uncertainty

[These excerpts are from an introductory article by Seth Fletcher, Jen Schwartz and Kate Wong in the September 2019 issue of Scientific American.]

      On July 8 President Donald Trump stood in the East Room of the White House and delivered a speech celebrating his administration’s environmental leadership. Flanked by his Secretary of the Interior David Bernhardt, a former oil and gas lobbyist, and EPA head Andrew Wheeler, a former coal lobbyist, Trump extolled his team’s stewardship of public lands, its efforts to ensure “the cleanest air and cleanest water,” and its success in reducing carbon emissions. In reality, Trump has opened up millions of acres to drilling and mining and sought to reverse multiple air- and water-pollution regulations. As for carbon emissions, they spiked an estimated 3.4 percent last year, and this administration is withdrawing the U.S. from the Paris climate change agreement that nearly every other nation on the planet is participating in.

      The speech was surreal but apparently strategic: It came on the heels of polls showing that Americans are growing increasingly worried about the environment. It remains to be seen whether Trump will sway environmentally concerned voters by using false claims, but clearly his team thinks that’s a possibility. Truly we live in interesting times. How did we get here, and how do we get out?...

      Uncertainty in the world makes us all the more susceptible to such campaigns. But it’s not all doom and gloom. By understanding how we instinctively deal with unknowns and how bad actors exploit the information ecosystem, we can mount defenses against weaponized narratives—and build mutual understanding to solve society's most pressing challenges.

Too Much of a Good Thing

[These excerpts are from an article by Claudia Wallis in the September 2019 issue of Scientific American.]

      More than half of American adults take vitamin pills. I’ve watched in wonder as some of my more health-conscious friends kick off their morning with an impressive array of multicolored supplements: A, C, D, calcium, magnesium, you name it. And it’s not just my friends….

      Most of this nutritional enthusiasm does no harm—apart from the budgetary kind—and for those with inadequate diets or special health concerns, supplements can do a world of good. But it is wise to keep in mind that doses that fax exceed the recommended dietary allowances (RDAs) set by the Institute of Medicine can be hazardous. A reminder comes from a recent study linking excessive B vitamins to a heightened risk of hip fracture….

      The B vitamin findings are reminiscent of a discovery made some 20 years ago that linked excessive vitamin A (retinal} with hip fractures….

      The bottom line is that although vitamins and minerals are essential for health, more is not necessarily better. Research shows, for example, that taking large amounts of beta carotene (a vitamin A precursor) seems to accelerate lung cancer in smokers, even though the nutrient may have anticancer properties in other contexts. Like everything in nutrition, vitamins are complicated. Just consider the fact that B6 plays a role in more than 100 different enzyme reactions. Perhaps because of that complexity, many seemingly logical uses of vitamins yield disappointing results. For instance, even though low blood levels of vitamin D correlate with greater risk of heart attacks and strokes, taking D supplements generally does not help, according to a 2019 analysis.

      Vitamins are vital when your diet is deficient. Willett thinks a daily multivitamin is a sensible insurance policy. The irony, he observes, is that the people most apt to take lots of supplements are educated folks with a healthy diet—in other words, those who need them the least.

When “Like” is a Weapon

[These excerpts are from an editorial by the editors of the September 2019 issue of Scientific American.]

      …recent disinformation campaigns—especially ones that originate with coordinated agencies in Russia or China—have been far more sweeping and insidious. Using memes, manipulated videos and impersonations to spark outrage and confusion, their targets transcend any single election or community. Indeed, these efforts aim to engineer volatility to undermine democracy itself. If we're all mentally exhausted and we disagree about what is true, then authoritarian networks can more effectively push their version of reality. Playing into the “us versus them” dynamic makes everyone more vulnerable to false belief.

      Instead of surrendering to the idea of a post-truth world, we must recognize this so-called information disorder as an urgent societal crisis and bring rigorous, interdisciplinary scientific research to combat the problem. We need to understand the transmission of knowledge online; the origins, motivations and tactics of disinformation networks, both foreign and domestic; and exactly how even the most educated evidence seekers can unwittingly become part of an influence operation. Little is known, for instance, about the effects of long-term exposure to disinformation or how it affects our brain or voting behavior….

      The pace of research must try to catch up with the rapidly grow-ing sophistication of disinformation strategies….

      Journalists must be trained in how to cover deception so that they don’t inadvertently entrench it, and governments should strengthen their information agencies to fight back. Western nations can look to the Baltic states to learn some of the innovative ways their citizens have dealt with disinformation over the past decade: for example, volunteer armies of civilian “elves” expose the methods of Kremlin “trolls.” Minority and historically oppressed communities are also familiar with ways to push back on authorities’ attempts to overwrite truth. Critically, technologists should collaborate with social scientists to propose interventions—and they would be wise to imagine how attackers might cripple these tools or turn them around to use for their own means.

      Ultimately, though, for most disinformation operations to succeed, it is regular users of the social Web who must share the videos, use the hashtags and add to the inflammatory comment threads. That means each one of us is a node on the battlefield for reality. Individuals need to be more aware of how our emotions and biases can be exploited with precision and consider what forces might be provoking us to amplify divisive messages.

      So every time you want to “like” or share a piece of content, imagine a tiny “pause” button hovering over the thumbs-up icon on Facebook or the retweet symbol on Twitter. Hit it and ask yourself, Am I responding to a meme meant to brand me as a partisan on a given issue? Have I actually read the article, or am I simply reacting to an amusing or enraging headline? Am I sharing this piece of information only to display my identity for my audience of friends and peers, to get validation through likes? If so, what groups might be microtargeting me through my consumer data, political preferences and past behavior to manipulate me with content that resonates strongly?

      Even if—especially if—you’re passionately aligned with or disgusted by the premise of a meme, ask yourself if sharing it is worth the risk of becoming a messenger for disinformation meant to divide people who might otherwise have much in common.

      It is easy to assume that memes are innocuous entertainment, not powerful narrative weapons in a battle between democracy and authoritarianism. But these are among the tools of the new global information wars, and they will only evolve as machine learning advances. If researchers can figure out what would get people to take a reflective pause, it may be one of the most effective ways to safeguard public discourse and reclaim freedom of thought.

Evolving Emotions

[These excerpts are from a book review by David C. Van Essen in the 13 September 2019 issue of Science.]

      Evolution, behavior, brains, consciousness, and emotions are topics of enduring fascination. In The Deep History of Ourselves, Joseph LeDoux embraces all five in earnest. His ambitious endeavor to cover them in an integrated fashion is successful in many respects, but controversial in others.

      …His primary motivation in writing the current book is to articulate and defend a major recent shift—indeed, an about-face—in how he conceives of and uses the term “emotion.”

      LeDoux now equates emotions with feelings and stipulates that feelings only exist in creatures having conscious self-awareness (autonoesis). He concludes that although other species might have emotions, we currently can only be sure that they occur in humans. Before delving into this, the other sections of the book warrant discussion.

      The book’s first half is devoted to evolutionary “deep history” It begins with theories on the origin of cellular life (though short shrift is given to the possible role of viruses). A major theme is that “behavior”— defined broadly as interaction with one’s environment—emerged early in evolution.

      Single-celled organisms show approach and avoidance behaviors to environmental cues, notes LeDoux, and some unicellular eukaryotes show evidence of learning and memory. More complex behaviors emerged with the appearance of nervous systems.

      LeDoux focuses on the emergence of intercellular communication via neuronal action potentials and chemical synaptic transmission. Puzzlingly, he fails to mention that many non-neural epithelial cells have action potentials and are electrically coupled to one another, which may have set the stage for signaling by primitive neurons.

      The second half of the book begins with a discussion of brains, behavior, emotion, and cognition in the broad context of vertebrate evolution. It progresses to considering the anatomical and functional specializations of the human brain. LeDoux is enamored of the idea that the frontal pole is a uniquely specialized region of human cerebral cortex, but his theory is speculative and left this neuroanatomist unconvinced….

      The book’s final sections return to LeDoux's controversial theory of emotion. What is an emotion, he asks, and who (or what) has them? Can a dog be thirsty, have a sense of fear, or experience pleasure and, if so, are these properly considered emotions? What about a rat, a frog, or a fly?

      Much of the debate surrounding this issue is fundamentally semantic, depending critically on how one defines “emotion.” By equating emotions with feelings that can only be experienced by creatures having autonoetic consciousness, LeDoux positions himself at one extreme of a broad spectrum.

      A narrow definition like his comes at a price. LeDoux advocates major terminological shifts, such as using “defensive survival” instead of “fear” when referring to nonhumans. Time will tell whether this gains traction but there are grounds for skepticism.

      Strong counterarguments to LeDoux’s perspective have been lucidly articulated by Ralph Adolphs and David Anderson in The Neuroscience of Emotion. In their view, emotions represent fundamentally distinct internal states. The neural circuits that mediate a given emotion vary greatly across species, they argue, but many emotion-related behaviors share core commonalities….

      Though at times speculative, LeDoux ultimately succeeds in putting behavior, brains, consciousness, and emotions into a broad evolutionary context. One does not need to agree with all of his arguments to appreciate, j his lucid and engaging synthesis.

A Humboldtial View of Mountains

[These excerpts are from an editorial by Christian Korner and Eva Spehn in the 13 September 2019 issue of Science.]

      In the early 19th century, when naturalists were busy cataloging Earth's inventory and separating the living world into labeled units, a 32-year-old explorer at the flanks of Chimborazo mountain in Ecuador—higher than anybody else had climbed by that time—saw the fog clearing, revealing an arena of tropical mountain life. According to his notes, this was the moment when Alexander von Humboldt coined the central paradigm of his scientific legacy: Everything is connected. Removing one factor or item will inevitably affect others. For Humboldt, born 250 years ago, life on Earth was a web of interactions. He was seeking generality and came up with an ecological theory in modern terms—one that has never ceased to be relevant.

      Humboldt was the first to note that life on mountains is not driven by elevation as such, but by the climate associated with elevation. He introduced the concept of the isotherm—a line connecting elevations of equal temperature—to link mountains of the Arctic, the Alps, and the Andean Chimborazo by treeline position: at sea level in the Arctic and rising to 4000-m elevation near the equator, with all climatic life zones rising in parallel. Indeed, modern data show that the global treeline follows a Humboldtian isotherm of a 6°C mean temperature for the growing season. The treeline isotherm became the best known and best explained biogeographic boundary on Earth, defining the low-temperature limit of tree growth, even when trees are absent locally because of logging or fire. Thus, Humboldt’s idea of linking the world's mountains by isotherms represented a breakthrough scientific concept.

      Humboldt also was the first to describe one of the most powerful “experiments” by nature—steep elevation gradients that compress life zones into 4 to 5 km of elevation, which would otherwise be separated by thousands of kilometers of latitude near sea level. Not surprisingly, by lumping contrasting climates onto a single slope, mountains became hosts for more diverse life than any other terrestrial system. Not only do mountains harbor a high concentration of endemic species in specific regions, but their ruggedness also creates contrasting exposure to sun and wind. The result is a myriad of different local niches for life, which explains why mountain ecosystems are so rich in biodiversity. And thanks to the tremendous diversity of local life conditions, mountains have always offered refugia for plants and animals. However, these biota are vulnerable to anthropogenic drivers of change, from agriculture and forestry to extractive practices and pollution.

      Excluding lowland hill country, mountains cover 12.5% of Earth's terrestrial surface outside of Antarctica and are inhabited by about half a billion people. This is where vulnerability comes into play: Through the forces of gravity, these populations live under the threat of floods, avalanches, and landslides. Another 3 billion people living in the forelands are influenced by mountains through the resources that they provide—water in particular—but also by the constraints that they impose, such as transport barriers….

      The unifying concept of climatic belts, with their specific flora and fauna and conditions for sustaining human life, across the globe, is Humboldt's legacy to modern mountain science. Scientific evidence across disciplines—from climatology to biology to social sciences and humanities—is showing how correct Humboldt was. Everything is connected. Our thinking and actions need to reflect this.

Cracked Canvases

[This excerpt is from an article by Jennifer Leman in the September 2019 issue of Scientific American.]

      …Pigments are chemicals that absorb certain light wavelengths and reflect others to produce specific colors. But some materials—such as those on morpho butterflies’ iridescent blue wings and the striking feathers of some hummingbirds—produce colors based on the size and spacing of microstructures on their surfaces, which interact with light wavelengths of different sizes.

      Many plastics form minuscule cracks, called crazes, when put under stress. Typically these fractures occur randomly throughout the material. But first exposing some plastics to light beams can selectively weaken them in places, where crazes will appear when the plastic is stressed….Depending on size and configuration, these cracks act as microstructures that produce specific colors….

Filters less Foul

[These excerpts are from an article by David L. Chandler in the September/October 2019 issue of MIT News.]

      Oil and water are famously reluctant to mix fully together. But separating them completely—for example, when cleaning up after an oil spill or purifying water contaminated through fracking—is a devilishly hard and inefficient process frequently dependent on membranes that tend to get clogged up, or “fouled.”

      A new imaging technique…could provide a tool for developing better membrane materials that can resist or prevent fouling….

      The fouling process is very hard to observe, making it difficult to assess the relative advantages of different membrane materials and architectures. The new technique could make such evaluations much easier to carry out, the researchers say.

      Using two dyes that fluo-resce at different wavelengths, the researchers labeled the fibers of the membrane with one and the oily material in the fluid with the other. Then, employing confocal laser scanning microscopy, they used two lasers—one to illuminate each dye—and controlled the position and depth of the lasers’ focus to collect stacks of 2D images at different depths. Their technique can build up a full 3D image showing the oil, fiber, or both, making it possible to see how the oil droplets are dispersed in the membrane….

Margaret Hamilton

[These excerpts are from an article by Cara Giaimo in the September/October 2019 issue of MIT News.]

      In 1961, Hamilton brought this outside-the-box approach to her next position, inventing a new error protocol for MIT’s massive, unruly SAGE air defense system. This computer took up a whole warehouse, and made “foghorn and fire engine sounds” when it crashed….

      So in 1964, when she saw an ad from the MIT Instrumentation Lab recruiting programmers to work on software for what would become the Apollo program, Hamilton jumped at the chance….

      She was soon promoted to “man-rated” software, where an error could jeopardize an astronaut’s life. Here, good code had to run correctly—but it also had to detect and make up for hardware malfunctions or mistakes made by the astronauts themselves. Hamilton tapped back into that spirit of what-if: What if someone flips this switch at the wrong time? What if an emergency occurs when everyone is busy? Accounting for these possibilities kept her up at night. “That’s all I thought about,” she says.

      Sometimes inspiration came from unexpected places. Hamilton would often bring her daughter, Lauren, to the lab with her on nights and weekends. Lauren, then four years old, liked to play astronaut in the team's simulators, and one day, pressing buttons at random, she caused a spectacular software crash. Hamilton investigated and found that Lauren had confused the program by keying in a pre-launch sequence, called P01, “in the middle of the mission,” she says.

      She asked the powers at NASA to let her add a safeguard to prevent that error in a real flight, and they laughed it off as too unlikely. But they let her make a note of it. When an astronaut did make that blooper during the Apollo 8 mission—the first manned flight orbiting the moon—it caused necessary navigational data to vanish, and they called Hamilton in to get it back. “I remember saying to a couple of guys there, ‘It’s the Lauren bug!’” she says, laughing.

      It was Apollo 11 that gave the team the greatest scare. Just as the Eagle was about to touch down on the moon, the astronauts were interrupted by five error messages warning that computing power was low. But because the software was so well designed, Houston trusted it to prioritize the most important aspects of the landing, and allowed the mission to proceed. The team had programmed the software to detect errors and recover from them, but watching it do that during Eagle's descent inspired “sheer terror,” she says….

Of Mice, Men and Computers

[These excerpts are from an article by Cara Giaimo in the September/October 2019 issue of MIT News.]

      …Later, in a 1948 paper called “A Mathematical Theory of Communication,” he explained how any communicable material—a poem, a photograph, a radio wave—could be broken down into units of pure information, a series of yeses and nos. These units “may be called binary digits, or more briefly bits,” Shannon wrote. Thus represented, the material could be stored, manipulated, or sent from one place to another, all with great fidelity....

      …Over and over, he bumped into seemingly intractable problems and found a mathematical way through, making sure to absorb their lessons for next time. Along the way, he “single-handedly laid down the general rules of modem information theory,” establishing the foundation for digital computing and becoming “a giant [in] the industry,” as an anonymous eulogizer wrote in the Times of London after his death in 2001….

      Like Shannon with his bits, Minsky realized that something recognizable as “intelligence” might arise from discrete and manageable parts. He spent his career delving ever deeper into the workings of the human mind, approximating what he found there with increasingly com-plex programs and machines….Minsky joined the MIT faculty in 1958, wrote a number of influential books, and helped to found both the Artificial Intelligence Lab—which later merged with the Lab for Computer Science to become CSAIL—and the Media Lab. He won the Turing Award in 1969….

Grow your own Nanotubes

[These excerpts are from an article by Jennifer Chu in the September/October 2019 issue of Technology Review.]

      Baking soda, table salt, and detergent are surprisingly effective ingredients for cooking up carbon nanotubes. A team of MIT researchers found that such sodium-containing household ingredients can catalyze the growth of carbon nanotubes, or CNTs, at much lower temperatures than traditional catalysts require, although a home oven wouldn't be hot enough to make it work. The discovery may enable CNTs to grow on a host of materials that would melt at higher temperatures, such as polymers and other substances, offering a way to make those materials stronger.

      Under an electron microscope, carbon nanotubes resemble hollow cylinders of chicken wire. Each tube is made from a rolled-up lattice of hexagonally arranged carbon atoms. The bond between carbon atoms is extraordinarily strong, and when patterned into a flat lattice (as in graphene) or a tube-shaped lattice (as in a CNT), such structures can have exceptional stiffness and strength.

      Researchers typically grow CNTs through chemical vapor deposition, in which a material such as a silicon wafer is coated in a catalyst—usually an iron-based compound—and placed in a furnace, through which carbon-containing gases flow. At temperatures near 800 °C, the iron starts to draw carbon atoms out of the gas, forming vertical nanotubes.

      The MIT researchers were experimenting with ways to grow CNTs when they noticed that one batch produced results different from what they expected….

      They tested a range of sodium-containing compounds, including baking L soda, table salt, and detergent pellets….Eventually, they upgraded to purified versions of those compounds.

      While iron catalysts form carbon nanotubes at around 800 °C, they found that sodium catalysts did so at around 480 °C. And after about 15 to 30 minutes in the furnace, the sodium simply vaporized away, leaving hollow carbon nanotubes behind….

The Original Moonshot

[These excerpts are from a letter by L. Rafael Reif, the President of MIT, in the September/October 2019 issue of MIT News.]

      …After all, when NASA realized that the moon landing would require a computer guidance system that was miniaturized, foolproof, and far more powerful than any the world had ever seen, they called MIT. What's more, the second person to set foot on the moon was Buzz Aldrin, ScD '63—the first astronaut to have a doctoral degree. (In fact, of the 12 humans who have walked lk on the moon, four graduated from MIT.)

      I was also drawn to the story of Margaret Hamilton….Among the first programmers hired for the Apollo project at MIT, she played a key role in developing the software that made the moon landing possible. (She was also one of the first to argue that computer programming deserved as much respect as computer hardware. So she insisted on a brand-new term: “software engineering.”)

      Indeed, the spirit of that magnificent human project speaks to our community’s deepest values and its highest aspirations. First: the power of interdisciplinary teams. Our society loves to single out superstars. Yet I expect that as graduates of MIT, you are already skeptical of stories of scientific triumph that have only one hero. In fact, among the most powerful lessons we teach our students is the importance of learning from each other, respecting each other, and depending on each other: the instinct for sharing the work and sharing the credit.

      As Margaret Hamilton herself would be quick to explain, by July 1968, the MIT Instrumentation Laboratory had employed nearly 1,000 people to work on Apollo software and hardware. And from Virginia to Texas, NASA engaged thousands more. In short, she was one star in a tremendous constellation of talent. And together, those stars created something impossible for any one of them to create alone.

      The story of the moon landing also reflects our community’s enthusiasm for bold ideas and “impossible” assignments, and it demonstrates just how much human beings can accomplish when we invest in research and put our trust in science.

      Yet for those of us alive at the time, the most important insight was the sudden, intense understanding of our shared humanity and of the preciousness and fragility of our blue planet. Fifty years later, those lessons feel more urgent than ever….

Forest Giants Are the Trees Most at Risk

[These excerpts are from an article by Elizabeth Pennisi in the 6 September 2019 issue of Science.]

      The biggest trees, standing tall through storms and harsh winters, may look invincible. But a series of recent studies analyzing the effects of lightning, drought, and invasive pests on forests indicates that for trees, size is not strength, and forest giants are dispropor-tionately vulnerable.

      …Large trees are also major storehouses of carbon—one estimate suggests they hold 50% of a forest's carbon—and their deaths release it into the atmosphere, which could exacerbate climate change.

      It makes sense that lightning targets the biggest trees, but the extent of the toll has emerged only now….In temperate regions, lightning blackens tree trunks or burns a tree down when it strikes, so it’s easy to see its effects. But in tropical forests…lightning leaves no obvious marks, possibly because the trees carry more water, although a struck tree may still die weeks or months later…. Each strike kills an average of five trees and damages 16 more as the bolt’s electricity hops from one tree to another….

      Drought could worsen it. Some studies had suggested that because the roots of small trees are too shallow to reach groundwater, they might be more vulnerable to drought than forest giants….

      In 2014 and 2015, the region was in the grip of the worst drought in 1200 years together with unusually hot weather. Before the drought, trees of all sizes died at about the same rate….But after 2014, when the severe drought began, 40% of the trees taller than 30 meters died, compared with 28% for medium-size trees and 16% for small trees….

      “Height is more important than any other factor,” including rainfall and temperature, for whether a tree survives drought….

      …scientists believe taller trees are more vulnerable in part because they have to pull water longer distances from the roots to their crowns. If conditions cause water in leaves to escape too fast, bubbles can form in a trunk's water-conduction channels, disrupting flow….Drought also weakens trees' defenses against bark beetles, which in turn carry pathogens that can kill the tree….

      About 14% of the world's conifers grow in drought-prone climates like the Sierra Nevadas, and global warming is expected to make droughts more common in those areas….

      Invasive pests, which are also on the rise because of human activity, are another scourge of big trees….

Amazon Fires Clearly Linked to Deforestation, Scientists Say

[These excerpts are from an article by Herton Escobar in the 30 August 2019 issue of Science.]

      Brazil’s government claims its policies aren’t responsible for the fires that are ravaging the Amazon rainforest and triggered worldwide indignation last week. President Jair Bolsonaro suggested nongovernmental organizations were setting the forest ablaze to discredit his government; his minister of the environment, Ricardo Salles, tweeted that “dry weather, wind, and heat” were to blame….

      Thousands of fires occur in the Amazon annually, but the numbers have risen since Bolsonaro became president on 1 January and began to encourage development. In satellite images, Brazil’s National Institute for Space Research (INPE) counted more than 41,000 “fire spots” between 1 January and 24 August, compared with 22,000 in the same period last year….The numbers are the highest since 2010, when the Amazon experienced a severe drought triggered by El Nifio and a warming of the North Atlantic Ocean. This time, climatic anomalies can’t explain the uptick, scientists say.

      Deforestation can, at least partly. To clear land for farming, settlers fell trees, remove valuable timber, and then set fire to the remainder. Recent INPE data showed deforestation to be on the rise, although Bolsonaro called the numbers “a lie” and had INPE Director Ricardo Galvao fired….

Stunning Skull Shakes Human Family Tree

[These excerpts are from an article by Michael Price in the 30 August 2019 issue of Science.]

      …After 3 years of analysis, researchers have dated the fossil to 3.8 million years old and identified it as Australopithecus anamensis, a hominin long thought to be the direct predecessor of the famed “Lucy” species, A. afarensis. The new fossil could reshuffle that ancient relationship….

      Researchers hail the skull as one of the most significant hominin discoveries in decades….

      …not everyone is convinced it clarifies the relations of the australopithecines, a genus of upright apes that lived between 4.2 million and 2 million years ago throughout eastern and southern Africa.

      A. anamensis was first identified in 1995, mostly on the basis of 4-million-year-old teeth and jaws from Kenya. Given the dates, plus several telltale anatomical similarities, most researchers concluded that A. anamensis gradually transitioned into and was replaced by A. afarensis, which lived from about 3.7 million to 3 million years ago.

      The new Ethiopian specimen, nalned MRD after Miro Dora, the site where it was found, was probably a male with a brain size of about 370 cubic centimeters, about that of a chimpanzee. He had jutting cheekbones, elongated canine teeth and oval-shaped earholes—all features that strongly suggest membership in A. anamensis rather than the bigger-brained, flatter-faced A. afarensis….The team dated the skull using the radioactive decay of isotopes of argon in the surrounding sediments….

Evidence Lights the Way

[These excerpts are from an article by Lizzie Wade in the 30 August 2019 issue of Science.]

      About 16,000 years ago, on the banks of a river in western Idaho, people kindled fires, shaped stone blades and spearpoints, and butchered large mammals. All were routine activities in prehistory, but their legacy today is anything but. The charcoal and bone left at that ancient site, now called Cooper’s Ferry, are some 16,000 years old—the oldest radiocarbon-dated record of human presence in North America….

      The findings do more than add a few centuries to the timeline of people in the Americas. They also shore up a new picture of how humans first arrived, by showing that people lived at Cooper’s Ferry more than 1 millennium before melting glaciers opened an ice-free corridor through Canada about 14,800 years ago. That implies the first people in the Americas must have come by sea, moving rapidly down the Pacific coast and up rivers….

      The Clovis people, big game hunters who made characteristic stone tools dated to about 13,000 years ago, were once thought to have been the first to reach the Americas, presumably through the ice-free corridor. But a handful of earlier sites have persuaded many researchers that the coastal route is more likely. Archaeologists have questioned the signs of occupation at some putative pre-Clovis sites, but the stone tools and dating at Cooper’s Ferry pass the test with flying colors….

      Over 10 years of excavations, the Cooper’s Ferry team uncovered dozens of stone spear points, blades, and multipurpose tools called bifaces, as well as hundreds of pieces of debris from their manufacture. Although the site is near the Salmon River, most of the ancient bones belonged to mammals, including extinct horses. The team also found a hearth and pits dug by the site's ancient residents, containing stone artifacts and animal bones.

      Radiocarbon dates on the charcoal and bone are as old as 15,500 years. In North America, few tree ring records can precisely calibrate such early radiocarbon dates, but a state-of-the-art probabilistic model placed the start of the occupation at between 16,560 and 15,280 year….

      It’s easy to see how seafaring people might have reached Cooper’s Ferry….Although the site is more than 500 kilometers from the coast, the Salmon, Snake, and Columbia rivers link it to the sea….

Evidence Lights the Way

[These excerpts are from an editorial by Adam Gamoran in the 30 August 2019 issue of Science.]

      These are dark times for science and public policy in the United States. In June, it was revealed that the White House suppressed the congressional testimony of a State Department scientist on the implications of climate change for national security—just the latest example of evidence undercut by ideology….What will it take to keep the light of evidence burning and ensure that the best science informs important decisions of our time?

      The current administration has taken steps to undermine the integrity of federal statistics agencies, eliminate or marginalize science units in federal agencies, slim down or drop expert advisory boards, remove scientific information from federal websites, and ban agency employees from using the term “scientific evidence” in budget requests. In June, President 'frump directed federal agencies to disband at least one-third of their expert advisory committees by 30 September.

      Nevertheless, there are signs that data, evidence, and rigorous evaluation persist….

      State and local leaders are also seeking to use evidence, often in collaboration with researchers. By investing in research-informed programs, for example, the New Hampshire Charitable Foundation has made progress on early childhood education, family and youth supports, substance abuse prevention, and education and career pathways….

      So how can research, science, and evidence remain integral to public policy? Public and private fenders must redouble their commitments to support scientific inquiry, as in 2018 when Congress increased the budgets of several science agencies after the administration bad proposed cuts. Philanthropy must also fund evidence-based solutions and the science behind them….More researchers should collaborate with policy-makers to develop research agendas, to increase the chances that research findings will be used….

      It’s clear that contributions from government, philanthropy, and research organizations are keeping evidence aglow, even in dark times. Let's make sure that such efforts continue to light the path ahead.

What Will Be Your Legacy as a Science Teacher?

[These excerpts are from an editorial by Ann Haley MacKenzie in the September 2019 issue of The Science Teacher.]

      …What is your legacy going to he as a science teacher? I contend our legacy revolves around the memories we make with our students. Having students complete mind-numbing worksheets that are quickly forgotten leaves science as a lifeless lump of coal in our students’ lives.

      The part of the brain that houses long-term memory sits close to the amygdala, the seat of our emotions. If you want students to remember key concepts, then you must somehow make them come alive in a way to evoke emotion in your students….

      Years later, students will return to you and make comments about what they remember from your teaching. Trust me, it won’t be about a mindless task. They will remember the atmosphere of the classroom, your laughter, the memorable projects, and how you made them feel. Were they investigative scientists in your classroom or a herd of cattle moved in and out from period to period with no at-tention to the wonders of science?

      Leave a legacy. Make memories. If we want our students to continue studying science, their lives depend on it.

Going for the Gut

[These excerpts are from an article by Deborah Halber in the MIT’s Summer 2019 issue of Spectrum.]

      In a tiny Malay village near an ancient tropical rain forest, MIT postdocs Mathieu Groussin and Mathilde Poyet were explaining through an interpreter that they wanted members of the Batek tribe to donate some poop.

      The villagers laughed. When they stopped laughing, they described how their toileting—which did not involve any actual toilets—took place privately, deep within the forest.

      …had traveled to Malaysia in March as part of a worldwide mission to preserve the biodiversity of human gut microbes. It was crucial to include hunter-gatherers like the Batek, because their diets and microbiomes are strikingly different from those of city dwellers….

      The human microbiome is made up of single-celled bacteria with hard-to-pronounce names like Akkermansia muciniphila, Faecalibacterium prausnitzii, and Parabacteroides goldsteinii. They live in our bodies in numbers that rival those of all our other cells combined, and they work so seamlessly with everything else that they have been likened to a separate organ. Each individual’s microbiome is unique, but researchers are becoming aware of differences among populations that appear tied to not only diet, but also to vaccinations, antibiotics, and exposure to environmental chemicals.

      To researchers, some of the most interesting bacteria are the 1000-plus species inhabiting the gut. These aid in digestion, immune function, and eradicating free radicals (atoms linked to aging and disease). There is growing evidence that the influence of gut microbiota extends as far as the brain and nervous system….

      Bacteria have evolved to coexist with humans. To adapt quickly to changes in their environment, gut microbiota harbor a vast number of genes they trade among themselves. The less gut bacterial diversity…the higher the rate of gene exchange—possibly an evolutionary survival mechanism in the presence of an enemy like antibiotics, which kill off healthy microbes along with dangerous bacteria….

      Urbanization and industrialization…are leading to an alarming loss of microbiome biodiversity, wiping out strains that could play crucial roles in human health. At the same time, advances in anaerobic culturing methods and gene sequencing now allow a vast majority of human gut bacterial species to be cultured, characterized, and preserved indefinitely….

From Vision to World Wide Web

[These excerpts are from a book by Nick Montfort that were included in the MIT’s Summer 2019 issue of Spectrum.]

      Probably even more familiar to us today than the Interstate Highway Network, which was formed, post-Futurama, beginning in the 1950s, is our World Wide Web, a global information system that is now accessible instantly not only at workstations and notebook computers, but also on phones. This system carries a tremendous number of commercial interactions along with an unprecedented store of information, and it also has a recognized inventor. Tim Berners-Lee proposed this system early in 1989 and implemented enough of the system to load the first Web page later that year. He did have support from others on the project, including Robert Cailliau, but Berners-Lee’s work and vision were at the core of the Web, and he is its first author.

      The World Wide Web (and the future-making work that preceded it holds several L important lessons for future-makers….

      Berners-Lee dedicated the Web to everyone in the world, asking for no royalties, filing for no patents, and ensuring that Web technologies would be unencumbered and free for anyone to use. Instead of becoming a monopolistic system limited to those in wealthy countries with financial resources, the Web—even if aspects of it present problems at times—has, as advertised, become remarkably worldwide and open to all sorts of businesses, universities, organizations, and individuals....

      Berners-Lee and his collaborators didn’t make up every concept that is the foundation of the Web—they were aware, directly and indirectly, of existing hypertext ideas. The success of the World Wide Web is surely due to two specific factors beyond determination and cleverness:

      First, the Web is a simple system, much less powerful than Nelson would like….But the Web doesn’t require any central authority—or, at least, it requires only the hierarchical aspects of the underlying Internet that were already there. The Web would be much less useful without the ultimately centralized Domain Name Service (DNS) that resolves verbal names such as “mit.edu” into numeric addresses. But this system was developed in the 1980s, and predates the Web. Once you can convert your domain names into addresses, your requests only need to route through the Internet to locate a Web server and retrieve information from it. A person who wants to set up a new Web server can just set one up without any interaction with a central registry. In the worst case, dealing with a central authority just means the equivalent of register-Ling a new domain….

      Second, the standards of the Web were offered to everyone rather than being restricted by patents or copyrights. Berners-Lee insisted that the Web not be encumbered, and there are concrete reasons this may have helped the system to succeed….

Power Forward

[These excerpts are from an article by Mark Wolverton in the MIT’s Summer 2019 issue of Spectrum.]

      Meeting the growing energy needs of our technological age while addressing global climate change is a daunting undertaking. That's why the MIT Energy Initiative (MITEI) continually draws together wide swaths of the Institute's intellectual, organizational, and policy resources to take on the challenge….

      Among its most visible projects is its series of “Future of...” studies, comprehensive multidisciplinary research reports that explore paths to meeting future energy demands under carbon dioxide emissions constraints. To date, MITEI has produced “Future of...” studies on energy sources such as solar, natural gas, coal, and geothermal, and on vital parts of the energy infrastructure, including the electric power grid and the nuclear fuel cycle.

      The latest report is The Future of Nuclear Energy in a Carbon-Constrained World. This title neatly sums up the study’s major point, which…is that “nuclear can and should play a big role in decarbonizing the power sector.”

      The study points out that reaching this goal will require not just technical innovations, such as new reactor designs, but also updated policy and business models, regulations, and construction techniques….

      Vast new natural gas resources have been tapped, and attention to climate change and the need for decarbonization have increased. The nuclear industry was hit hard by both the 2008 economic crisis and the zoii nuclear accident in Fukushima, Japan.

      Furthermore, emerging technologies con-tinue to increase the value of nuclear energy in terms of decarbonization. Fourth-generation reactor designs are more efficient and more accident-tolerant; today's small, modular reactors offer more flexibility and versatility than traditional large-scale nuclear plants….

      Such ideas capitalize on the fundamental function of a nuclear reactor: creating heat. Typically, plants create steam to turn turbines that generate electricity, but heat itself can also drive industrial processes—a concept made even more attractive by the higher operating temperatures available with advanced reactor designs.

      In addition to exploring new technology, however, Buongiorno and his colleagues also examined the policy and economic issues that have stalled the growth of nuclear power. Their analysis shows that trying to meet energy needs solely through renewable sources will raise the cost of decarbonization while slowing its progress. The study makes the case that, ultimately, nuclear is an important avenue to a low-carbon future….

Food Process

[These excerpts are from an article by Michael Blanding in the MIT’s Summer 2019 issue of Spectrum.]

      In a typical supermarket, all of the fresh food—fruits and vegetables, meats, dairy, and bread—line the perimeter of the store. The expansive middle, meanwhile, features aisle after aisle of processed foods….

      The story begins with World War II, when the country mobilized to feed 6 million soldiers stationed abroad in 23 different climatic regions. “All of the food they ate was made in America and shipped to wherever they were,” Fitzgerald says. At the center was the US Army Quartermaster Corps, which exerted a profound, yet understudied, effect on the trajectory of our nation’s agricultural system….

      The military solved its provisioning problems by working with food companies to create food described as “time-insensitive”—bland, processed meals that could withstand the rigors of overseas shipping and be carried by soldiers into battlefields anywhere. That meant heavily processed and preserved foods like cans of beef stew and chili con came, “meat bars” (made of compressed and dehydrated meat), biscuits, cookies, and candy that could give soldiers energy and nutrients in a hurry.

      To accommodate this rapid shift, the Quartermaster Corps requisitioned massive quantities of produce from distinct areas—fruits from California, dairy from Wisconsin and New York, grains from the Midwest—consolidating industries geographically. “Before the war, farmers grew a little bit of everything, but that became less realistic as the war developed,” Fitzgerald says. “This big national crisis turned around the way agriculture was done.”

      After the war, those changes stuck. Midwest farmers, for example, suddenly found themselves with bumper crops of wheat and corn with no obvious civilian market. Food companies stepped in, creating new products to utilize the surplus. “They had to turn it into something—so welcome, Doritos!” Fitzgerald says. To make these processed foods more palatable to civilians, the companies tapped new technologies in coloring and spray-on flavor to create an amazing variety of foods—a trend that continues to fill the middle aisles of supermarkets today.

      Fitzgerald says the story of 20th-century processed food is an intriguing lens through which to view the history of technology generally especially in a place like MIT that has so much faith in the positive potential of technology….

Probing an Evolutionary Riddle

[These excerpts are from an article by Elizabeth Culotta in the 23 August 2019 issue of Science.]

      …“Natural selection will never produce in a being anything injurious to itself,” Darwin wrote in On the Origin of Species.

      But in humans, natural selection apparently did exactly that. Suicide is the leading cause of violent death, striking down about 800,000 people worldwide each year—more than all wars and murders combined, according to the World Health Organization….

      Applying an evolutionary eye to epidemiological data and human cultures, Humphrey concluded that suicide was likely the tragic byproduct of a vital adaptation: the sophisticated human brain….the ravages of suicide are a consequence of human intelligence and have shaped our minds and cultures….

      …if what makes us human has put us at risk, it has also saved us. They argue that, faced with the persistent threat of suicide, humans have developed a set of defenses, such as religious beliefs, that are crucial elements of our culture and psychology….

      Soper calls his model pain and brain: When faced with agonizing pain, a sophisticated mind can think of death as an escape….All organisms feel pain, which is vital to avoiding threats. But humans are arguably unique in our big brains, which allow us to have complex social lives, culture, and an awareness of death.

      …the combination could explain why suicide is both unique to and widespread among humans, having been reported in all types of human society, as varied as hunter-gatherer groups and industrialized nations. A 4000-year-old Egyptian poem mentions suicide, as do historical records from every era since….In the United States in 2017, about 4% of all adults, or nearly 10 million people, thought seriously of suicide….That’s more than 200 times the number who died by suicide that year.

      In contrast, Humphrey and Soper find no convincing evidence that other animals intentionally end their lives. And although suicide rates are rising among U.S. adolescents, suicide remains exceedingly rare among children: Of the more than 47,000 people in the United States who died by suicide in 2017, only 17 were ages 8 to 10; no such deaths were reported at younger ages.

      Although suicide appears across human cultures, it is also a rare event….

Color and Incarceration

[These excerpts are from an article by Lydialyle Gibson in the September/October 2019 issue of Harvard Magazine.]

      …federal policies—shaped by presidential administrations and endorsed by Congress—ratcheted up surveillance and punishment in black urban neighborhoods from the 196os through the 198os, how criminalization was steadily expanded, and how all of this was driven by deeply held assumptions about the cultural and behavioral inferiority of black Americans.

      …the contemporary carceral state began to take hold, not under law-and-order conservatives like Ronald Reagan or Richard Nixon, the men usually held responsible, but under liberals, most notably Lyndon Johnson, whose Great Society social-welfare programs were enacted at the height of the civil-rights movement….

      …In March 1965…President Johnson sent three bills to Congress that epitomized the federal government’s ambivalent response to the civil-rights movement: the Housing and Urban Development Act, the Voting Rights Act, and the Law Enforcement Assistance Act. The latter bill, signed into law a month after violent uprisings in Los Angeles's segregated Watts neighborhood, marked the official start of the War on Crime. For the first time in U.S. history, the federal government began to take a direct role in local police, courts, and prisons.

      Three years later, the Safe Streets Act created the Law Enforcement Assistance Administration, which figures as a main culprit in her account….And it helped widen local law-en-forcement patrols and surveillance operations in cities with large African-American populations.

      Meanwhile, Johnson’s poverty initiatives increasingly gave way to crime-fighting, as programs dedicated to health, housing, education, recreation, and job training came to be partly—or sometimes wholly—administered by law-enforcement agencies. Even as federal policymakers recognized that joblessness, failing schools, inadequate housing, and inequality lay at the root of urban ills—including crime—they repeatedly turned to law enforcement as the solution.

      …the idea of a self-perpetuating “tangle of pathology” among black families. All three…came to view black poverty "as a fact of American life," and black crime and violence as innate. Their ideas helped push the Nixon administration, several years later, toward a belief that black cultural pathology, not poverty, was the real cause of crime.

      And so, in low-income black neighborhoods, law enforcement became a ubiquitous part of the social and political landscape, and strategies intended to identify residents at risk of becoming criminals encouraged authorities to provoke interactions with them, creating, Hinton notes, a feedback loop of crime and enforcement….

      The Nixon administration ushered in dramatically more punitive policies, withdrawing further from social reforms and rehabilitative measures in favor of harsher punishments: longer sentences, preventive detention, broad wiretapping, no-knock raids. Sting operations often created crime, setting up decoy fencing operations and whole underground economies that incentivized the poor and unemployed to steal from one another….

      Her narrative carries through the administrations of Gerald Ford, under whom juvenile-detention facilities multiplied and white youths were treated as merely troubled while black youths were dealt with as criminal; and of Jimmy Carter, who, despite his progressive intentions channeled millions of federal dollars to public-housing authorities for surveillance and patrols that failed to improve safety but made housing projects into pipelnes to prison….

      Today, roughly 2 million people are incarcerated in this country, 60 percent of them African American or Latino. The United States, with 5 percent of the global population but 25 percent of its prisoners, is home to the largest prison system in the history of the world, with an incarceration rate that is five to io times that of peer nations. Altogether, the federal, state, and local penal systems cost taxpayers $80 billion per year, and some states…spend more money imprisoning young people than educating them….

If You Give a Baby a Peanut

[These excerpts are from an article by Claudia Wallis in the August 2019 issue of Scientific American.]

      Few things are more subject to change and passing fancies than dietary advice. And that can be true even when the advice comes from trusted health authorities. A dozen years ago the standard recommendation to new parents worried about their child developing an allergy to peanuts, eggs or other common dietary allergens was to avoid those items like the plague until the child was two or three years old. But in 2008 the American Academy of Pediatrics (AAP) dropped that guidance, after studies showed it did not help. And in its latest report, issued in April, the AAP completed the reversal—at least where peanuts are concerned. It recommended that high-risk children (those with severe eczema or an allergy to eggs) be systematically fed “infant-safe” peanut products as early as four to six months of age to prevent this common and sometimes life-threatening allergy. Children with mild or moderate eczema should receive them at around six months.

      These are not whimsical changes. They match advice from a federal panel of experts and reflect the results of large randomized studies….Another trial…found that after parents carefully followed a protocol to begin feeding peanut protein, eggs and four other allergenic foods to healthy, breastfed infants between three and six months of age, the babies had a 67 percent lower prevalence of food allergies at age three than did a control group. The results were strongest for peanuts, where the allergy rate fell to zero, compared with 2.5 percent in the control group. Egg allergies also fell….

      How food allergies develop and why they have become so commonplace remain dynamic areas of research. Both the allergies and eczema (a major risk factor) have been on the rise. A 2010 study…found that the prevalence of childhood allergies more than tripled between 1997 and 2008, jumping from 0.6 to 21 percent….

      Eight foods account for 90 percent of food allergies: cow’s milk, eggs, fish, shellfish, tree nuts, peanuts, wheat and soybeans. Some scientists believe this is so because these foods contain proteins that are unusually stable to digestion, heating and changes in pH and are therefore more likely to cause an immune response.

      Early dietary exposure is now the confirmed preventive strategy for peanuts and, pending more research, perhaps the other foods, although this is more easily said than done….

A Crazy-Sounding Climate Fix

[These excerpts are from an article by Rob Jackson and Pep Canadell in the August 2019 issue of Scientific American.]

      Carbon dioxide in the atmosphere blew past 415 parts per million this past May. The last time levels were this high, two or three million years ago, the oceans rose tens of meters, something likely to happen again as Earth’s ice melts over the next 1,000 years.

      To replace bad news with action, we need hope—a vision for restoring the atmosphere. Think about the Endangered Species Act: it does not stop at saving plants and animals from extinction; it helps them recover. When we see gray whales breaching on their way to Alaska every spring, grizzly bears ambling across a Yellowstone meadow, bald eagles and peregrine falcons riding updrafts, we are celebrating a planet restored. Our goal for the atmosphere should be the same….

      We are not sayingincreasing CO2 is a good thing in and of itself. The gas that concerns us is methane, which leaks from wells and pipelines; bubbles up when organic matter rots in landfills and rice paddies; emerges from the digestive systems of cattle and from the manure piles they leave behind; and more. The good news about methane is that it remains in the atmosphere for a far shorter time than CO2 does. The bad news is that methane is vastly more efficient at trapping heat—more than 80 times more, in the first 20 years after its release—which makes it, pound for pound, a bigger problem than carbon.

      We want to remove methane from the air and then use porous materials called zeolites to turn it into carbon dioxide. Zeolites can trap copper, iron and other metals that can act as catalysts to replace methane's four hydrogen atoms with two oxygens. Because a methane molecule holds more energy than carbon dioxide, the reaction typically runs to completion if you can jump-start it. Furthermore, by releasing the carbon dioxide back into the air instead of capturing it, you make the process less expensive and lengthen the life of the zeolites.

      Researchers around the world are already studying zeolites and other materials to convert methane to methanol, a valuable feedstock for the chemical industry. Making methanol is a halfway point in our reaction, tacking one oxygen atom onto each methane molecule. No one seems to have considered finishing the job by making carbon dioxide in the same way because carbon dioxide is not valuable like methanol. We should consider it now.

      Another surprise about our proposal is that you could restore the atmosphere by removing “only” three billion metric tons of methane. Doing so would generate a few months' worth of industrial carbon dioxide emissions but eliminate up to one sixth of overall warming. That is a good trade by any measure.

      What we propose will not be easy to accomplish. Methane is uncommon: whereas the atmosphere currently holds more than 400 molecules of carbon dioxide for every million molecules of air, methane accounts for only two or so out of a million. That makes pulling it from the atmosphere harder than keeping it from entering in the first place. We will need other things to work as well. To give companies, governments and individuals financial incentives to do this, there has to be a price on carbon or a policy mandate to pay for removing methane. We also need research on the large arrays needed to capture methane from air. And of course, we need to fix methane leaks and limit emissions from other human sources. But we cannot eliminate those emissions entirely, so we would have to continue removing methane from the atmosphere indefinitely.

      Restoration of all the gases in the atmosphere to preindustrial levels may seem unlikely today, but we believe it will occur eventually. Such a goal provides a positive framework for change at a time when climate action is sorely needed. Stabilizing global warming at 1.5 or two degrees Celsius is not enough. We need the planet to recover.

Should Kids Learn to Code?

[These excerpts are from an article by Zeynep Tufekci in the August 2019 issue of Scientific American.]

      The government is behind it. In his 2016 State of the Union address, President Barack Obama said that the US. should offer “every student the hands-on computer science and math classes that make them job-ready on day one.” Soon after, he launched a $4-billion Computer Science For All initiative.

      Technology companies are enthusiastic. Amazon wants to teach coding to 10 million kids a year through its Amazon Future Engineer program. Facebook, Microsoft, Google and others have similar projects of varying scale and scope. Many parents are eager, too….

      So should you sign your kid up for a programming camp? t Insist they take computer science classes? Maybe, maybe not….

      Programming was fun for me. But what about the child who’s not so enthusiastic? Should he or she be made to learn programming because it could lead to a job someday? I would hold off: it’s unlikely we will be programming computers the same way in the decades ahead that we do now….

      What matters, then, for the future of this kind of computer work? The technical side is mostly math: statistics, linear algebra, probability; calculus. Math remains a significant skill and is useful for many professions besides programming. It's essential for everyday life, too. And algorithmic thinking doesn't have to come from computer coding. Some math and an appropriate learning experience via cooking, sewing, knitting—all of which involve algorithms of a sort—can be valuable….

      So should you let an interested child enroll in a coding camp? Of course. Should kids play around with Scratch or do an Hour of Code tutorial to see if that captivates their interest? Absolutely. But no worries if they want instead to learn how to make cupcakes, sew pillows or pajamas, or climb trees.

      We need to make sure youngsters do not think of the world as forcing them to choose between math and science on the one hand and social sciences and humanities on the other. The most interesting, and perhaps most challenging, questions facing us will be right at that intersection—not in the tiny, closed worlds we like to build for fun.

The Big Slowdown

[These excerpts are from an article by Wade Roush in the August 2019 issue of Scientific American.]

      On June 22, 1927, Charles Lindbergh flew into Dayton, Ohio, for dinner at Orville Wright's house. It had been just a month since the young aviator’s first ever solo nonstop crossing of the Atlantic, and he felt he ought to pay his respects to the celebrated pioneer of flight.

      Forty-two years later, on July 16, 1969, Apollo II astronaut Neil Armstrong was allowed to bring a personal guest to the Kennedy Space Center to witness the launch of NASA’s towering Saturn V rocket. Armstrong invited his hero, Charles Lindbergh.

      That’s how fast technology advanced in the 20th century. One man, Lindbergh, could be the living link between the pilot of the first powered flight and the commander of the first mission to another world.

      In our century, for better or worse, progress isn’t what it used to be. Northwestern University economist Robert Gordon argues that by 1970, all the key technologies of modern life were in place: sanitation, electricity, mechanized agriculture, highways, air travel, telecommunications, and the like….

      Since 1970 the only notable outlier has been the exponential increase in computing power, which has trickled down to consumers in the form of the Internet and our ever present mobile devices. But in most other ways, Gordon argues, the lives of people in developed nations look and feel the same in 2019 as they did in 1979 or 1989….

      Consider consumer robotics. There’s enormous potential for robots to help us with housework, education, entertainment and medical care. But home robotics companies seem to keep folding….

      Our century’s one signature technology achievement is theme iPhone. And at this point, we’ve had smartphones in our pockets long enough to begin to appreciate their dangers. Meanwhile the list of potentially world-changing technologies that get lots of press ink but remain stubbornly in the prototype phase is very long. Self-driving cars, flying cars, augmented-reality glasses, gene therapy, nuclear fusion. Need I continue?...

Gun Research Needs More Firepower

[These excerpts are from an editorial by by the editors of August 2019 issue of Scientific American.]

      …That adds up to 136,000 Americans harmed or killed annually by gun violence. Worse, the death side of this sad ledger is growing….Guns are a clear and present danger in this country, where there are about 393 million civilian-owned firearms—more than enough to put one in the hands of every man, woman and child and amounting to the highest rate of gun ownership in the world by far.

      The tremendous toll makes gun violence a huge public health problem. Yet unlike other pressing health threats, Americans have few ideas about the most effective prevention strategies because there has been almost no large-scale research on the issue.

      All that could change this year. In an appropriations bill this spring, the U.S. House of Representatives included $50 million to be used for such studies by the CDC and the National Institutes of Health—the first time in decades that this kind of support has been given. If the U.S. Senate concurs and the bill becomes law, researchers need to jump at this opportunity.

      Congress created the research gap in the first place, so it is right for Congress to fix it. In 1996, after a series of studies linked gun ownership to increased violence and crime and prompted an antiresearch campaign from the National Rifle Association of America (NRA), legislators inserted language into the CDC’s budget bill that said no money could be used to “promote gun control.” Congress also zeroed out the agency’s budget for firearms research. The message was clear, and federally supported science in this area ground to a halt.

      Since then, dozens of small-scale studies have been carried out—research comparing the effects of licensing laws in one county or state to laws in another, for instance. But none has had the power of large investigations that look at the effects of various kinds of interventions across the entire country and that involve tens of thousands of people. This is the kind of science that showed us the safety and health advantages of using seat belts, quitting smoking and reducing air pollution.

      Experts have identified many areas where our firearms ignorance is killing us, gaps that scientists should now move to fill. For one, we cannot answer basic questions about people who commit gun violence—the percentage of them who legally possessed the guns they used, for example, or how those firearms were acquired. Studies of possession and acquisition patterns would give us a sober assessment of whether existing permitting, licensing or background-check laws are actually being used to disarm dangerous people—including those who intend to harm themselves through suicide.

      We also need information on the best ways to stop underground gun markets, where weapons are often sold to people who cannot obtain them from a licensed gun shop. The way to get a solid answer is through research that traces guns in a large number of cities with regulations of varying strictness. There is also a crying need to evaluate violence-prevention policies and programs based on data about individuals who participate in large randomized controlled trials—the scientific gold standard for determining causes and effects.

      None of this research infringes on Second Amendment rights to firearm ownership. It does, however, promote other, unalienable rights set out in our Declaration of Independence—“Life, Liberty and the pursuit of Happiness”—and helps to stop them from being taken away at gunpoint.

Choosing Wisely

[These excerpts are from an article by Aron K. Barbey in the 16 August 2019 issue of Science.]

      Examining “why smart people make dumb mistakes,” The Intelligence Trap presents an accessible and engaging discussion of the nature of human intelligence. The reason for the paradox…is that people with a high IQ are often unaware of the limits of their understanding and are therefore susceptible to poor judgment.

      …This work presents evidence that standard IQ tests fail to measure critical thinking skills that are at the heart of decision-making, and as a result, high IQ does not guarantee competent decisions.

      To illustrate the role of critical thought in decision-making, consider the following example from the Cognitive Reflection Test presented in the book: “A bat and a ball cost $1.10. The bat costs $1.00 more than the ball. How much does the ball cost?” Although “10 cents” immediately comes to mind, the application of logic and mathematics allows us to generate the correct solution (5 cents)….

Science Can’t Be Taught in a Vacuum

[These excerpts are from an article by David R. Wessner in the 9 August 2019 issue of Science.]

      The news spread quickly. A student at the small liberal arts college where I am a biology professor had allegedly posted anti-Semitic neo-Nazi rhetoric on social media. Faculty members and students alike were shocked. The bubble of our close-knit community had burst; the realities of the external world were now the realities of our internal world, too. In the hours and days that followed, we all asked, “How could this happen?” Students asked another question, too: “Why don’t faculty in our STEM courses discuss these issues with us?” This second question troubled me. I and other STEM (science, technology, engineering, and math) faculty members at my institution do explore social and political issues in our courses. But our students were telling us that, as a whole, we fell short.

      I make a point of presenting science within a social context. I include issues of social justice in my courses and talk with my students about current events involving hate speech and violence. But I didn’t always. Why should I? After an, I was trained to be a scientist. As a graduate student in the late 1980s, fascinated by the biology of HIV and hoping to launch a career at a primarily undergraduate institution, I thought my mission was clear: Help my students understand and appreciate this amazing science. Examining the lived experience of HIV/AIDS wasn’t part of the plan.

      …I realized that science can’t be studied or taught from the confines of an ivory tower. Science needs to be studied holistically and taught with compassion and empathy.

      …I couldn’t discuss recent advances in medicine without acknowledging the health care disparities in our country. Initially my classroom forays into social justice were limited, focusing on issues—The Immortal Life of Henrietta Lacks, the Tuskegee syphilis experiments, the Eugenics Board of North Carolina—that were very closely related to the science we were discussing. I was encouraged that, in course evaluations and informal chats, students said they appreciated looking at biology more broadly.

      As I became increasingly aware of how science intersects with social issues, I broadened my approach. When I taught about HIV transmission, I brought up gender-based violence, needle exchange programs, and sex work decriminalization. Through the lively, robust conversations that followed, we all gained a more nuanced view of the science—and the world.

      So, what about the hateful rhetoric allegedly posted by one of our students? It may not have been directly related to the content of my courses, but it was directly related to our lives as human beings. My students needed to process this troubling occurrence, and I needed to make my classroom a safe space to discuss it….

      Treating my classroom as separate from the outside world is idealistic at best and foolhardy at worst. Science does not exist in a vacuum. Our students do not live in a vacuum. Yes, I’m a scientist, but I’m also a person living in a complex world. So are my students.

Math on Trial

[These excerpts are from an editorial by Nathaniel Persily in the 9 August 2019 issue of Science.]

      Can science help take the partisanship out of politics? To some extent, that was the question the U.S. Supreme Court confronted in this year’s blockbuster partisan gerrymandering case. The Court answered “no” and, by doing so, delivered an object lesson in the limits of math and science to settle the most political of constitutional questions.

      The Supreme Court has wrestled for decades with the problem of how to determine when partisanship in the redistricting process becomes so excessive that it violates the Constitution. As with pornography and the First Amendment, it never sufficed for the Court to say, “I know it when I see it.” The Court sought an “administrable standard” to separate tolerable levels of partisan consideration in the redistricting process from intolerable levels of gerrymandering. And in a 2004 Pennsylvania case, Justice Anthony Kennedy all but invited scientists and lawyers to come up with new ideas for clear constitutional tests.

      Mathematicians and data scientists rose to the challenge. Specialists in geometry proposed new measures of district compactness, computer scientists offered new ways to randomly generate thousands of plans to assess an enacted plan’s partisanship, and “teched-up” political scientists suggested new notions crf “partisan symmetry” or “wasted votes” to ensure political fairness. These methods and others were offered in cases such as the ones from North Carolina and Maryland that made their way to the Supreme Court this year.

      For the most part, each of these methods tried to prove the obvious: that egregious partisan gerrymanders were as biased and unfair as the subsequent election results proved them to be. But the Court could never rally around a single “administrable standard”—one that could be easily stated and operationalized as a matter of constitutional law. This was particularly important in the gerrymandering context given the high political stakes involved and the risk that judicial decisions would be seen as picking partisan winners and losers.

      With the critical replacement of Justice Anthony Kennedy with Justice Brett Kavanaugh, the Court then had a five-member majority willing to put a nail in the coffin of partisan gerrymandering claims. In an opinion for that new majority, Chief Justice John Roberts explained why the problem of partisan gerrymandering was simply too difficult and too political. All the math presented by the plaintiffs, the lower courts, and the dissenters was largely irrelevant for the majority because it did not provide a bright line rule derived from arithmetic akin to “one person, one vote.”

      …Judges often worry that “you can find statistics to support anything” (as I once heard a lawyer argue in a redistricting case). And in today’s highly polarized political environment, judges know that whatever the merits of their decision in a redistricting case, they will be accused of favoring their own preferred party.

      All is not lost, however, for scientists wishing to see their favorite method enacted into law. Although the federal courthouse door is shut to them, the state courts remain open. And for the entrepreneurial, legislation at the state level—through popular initiatives and action by less politically riven legislatures—has proven effective recently. Indeed, scientists should feel particularly at home in using the states as “laboratories of democracy” (as Supreme Court Justice Louis Brandeis described them in 1932). Should they find a standard that works, maybe some future U.S. Congress—admittedly, quite far in the future—will provide for national standards that the Court could not find in the Constitution.

Fossils Show Large Predator Prowled Cambrian Sediments

[These excerpts are from an article by Joshua Sokol in the 2 August 2019 issue of Science.]

      In the summer of 2018, paleontologists hammering away at rocks high in the Canadian Rockies turned up hundreds of specimens of an unknown, but evidently hyperabundant creature. With a hand-size carapace that looks like it was sketched out in science fiction concept art, the diggers nicknamed it “the spaceship”….Now, they’ve given the creature its first scientific description and a name: Carabroraster falcatus—after the famed Millennium Falcon starship from Star Wars….

      The ship was one of the largest known animals of its day to churn up the sea floor. It sailed in fleets over muddy ocean sediment, plying its unusual claws in the hunt for small prey.

      Most fossils of the animal showed only hard parts. But one specimen preserved the entire creature: a carapace with two eyes peeking out from either side, trailed by soft, undulating flaps for swimming….

      The fossils come from the Burgess Shale, a formation that for more than a century has yielded a strange and world-famous menagerie living roughly 507 million years ago, during the first bloom of animal life on Earth. During this period, burrowing organisms and their would-be predators like trilobites began an evolutionary arms race that may have helped spur the explosion of new forms. But most creatures were small, and no digging carnivores of this size had come to light.

      Cambroraster had a round mouth lined with toothlike plates, fronted with comblike claws it could hold out like a basket. Its eyes sat in deep notches that give the carapace its signature “spaceship” look….

      Radiodonts offer a glimpse of how today’s arthropods evolved their now-standardized body plan from stranger beginnings. The most famous radiodont is the free-swimming Anomalocaris, the Cambrian’s iconic meter-long apex predator. Others in the group were filter feeders, and now Cambroraster shows that some scrounged the sea floor like modern-day horseshoe crabs. Given that radiodonts filled so many ecological niches, it’s “surprising they got out-competed….”

      In 2018, the ROM team unearthed dozens of separated carapaces and claws in single layers of shale, suggesting C. falcatus individuals had congregated and then molted their exoskeletons, huddling together for safety or to reproduce, like some arthropods do today….

Time’s Up, CO2

[These excerpts are from an editorial by Marcia McNutt in the 2 August 2019 issue of Science.]

      Forty years ago this summer, a small group of atmospheric and ocean scientists met in Woods Hole, Massachusetts, to project the future impacts on Earth's climate from atmospheric release of carbon dioxide (CO2) from fossil fuel combustion….On the basis of then-current trends, the 1979 committee, led by Jule Charney of the Massachusetts Institute of Technology, assumed that atmospheric CO2 concentrations would reach double the preindustrial values sometime in the first half of the 21st century. They calculated that as a result, the average global surface temperature would increase by 3° ± 1.5°C, with the greatest warming at high latitudes—the first assessment of its kind. The Charney committee also noted in the models a lag on the order of decades between CO2 release and the resulting temperature rise. This delay, from disequilibrium effects with the ocean, masks pending temperature increases long before they are apparent.

      Fast-forward to 2019, and these calculations of the sensitivity of climate to a doubling of CO2 have proven to be remarkably on target. Indeed, on the basis of today’s more sophisticated climate models, the Intergovernmental Panel on Climate Change confirms the climate sensitivity proffered by the Charney report. Furthermore, the lag between emission and resulting temperature increases has contributed to society's inaction on a degree of warming to which the planet is already committed from existing emissions. Four decades later, time is running out to control greenhouse gases. What else can scientists do to spur action to avert the worst impacts of climate change?

      Back in 1979, without insight as to what revolutions might reshape the world economy their grandchildren would inherit, or how the biosphere might create feedbacks, the Charney committee focused on what they could estimate: the radiative effect of CO2 in the atmosphere; the negative feedback from clouds; and the ability of the oceans to absorb atmospheric heat. Since then, our scientific understanding of the impacts of climate change has grown well beyond just surface temperature change, and we have deepened our knowledge about the roles of clouds, oceans, aerosols, and other non-CO2 greenhouse gases. In particular, the science of attributing changes in the frequency and severity of extreme weather events to climate change drivers has been building credibility.

      Whether the extreme event is a heatwave, flood, drought, wildfire, or hurricane, demonstrating to the public how climate change is amplifying the negative impacts of these events can spur more immediate action, even before the most catastrophic warming is upon us. Opinion polls reveal that a majority of Americans are worried about extreme heat, flooding, drought, or water shortages. However, even those who do view climate change as an important national issue rank it well down the list after health care, jobs, and the economy. Geoscientists must work collaboratively with health care professionals, economists, and engineers to link the changing impacts of extreme events and their aftermath to climate change while the effects are still being experienced. This approach could well convince people that climate change is about health, jobs, and the economy.

      The Charney report demonstrates the power of scientific prediction. Since its release, scientists have built a formidable evidence base on climate change. At no time since 1979 has the science backed down from its dire predictions for the prospects of human civilization to prosper in a world warming well beyond limits encountered in all of human history. The scientific community must better connect the issues with what now matters to the public, so that the evidence is acted upon for the benefit of society.

Small Wonders

[These excerpts are from an article by Lynn Dicks in the 26 July 2019 issue of Science.]

      When Beethoven was writing his famous fifth symphony in 1806, the ink in his quill was almost certainly a by-product of the quirky lifestyle of a tiny wasp. A thousand species of oak gall wasp (Hymenoptera: Cynipidae, Cynipini) induce gall formation, mostly in oak trees. The “oak apple” galls, which protect and provide food for the young wasp larvae, contain high concentrations of tannic acid. When crushed and fermented with iron salts (for example, iron sulfate or rusty nails), the galls produce gall wasp ink, which is nonsoluble, long lasting, and without lumps. It was the most popular ink in Europe from the 11005 to the 1800s.

      Though wasp-produced inks have fallen out of favor, insect decline has entered the public consciousness in a big way recently. People have been worrying about bees for some time, but our anxiety has recently extended to all insects, fueled by datasets showing startling rates of decline, news stories about “insectageddon,” and a gut feeling that there used to be a lot more insects around….

      One reason for concern is that insects are intricately involved in our food production and waste management systems. When a million head of cattle were grazing Australia in the early 20th century, the 9 million metric tons of dung they produced every year fouled pastures and led to a plague of flies because there were no native dung beetles willing to consume the cow pats and recycle the nitrogen to the son. The problem was solved in the 1960s by introducing African dung beetles. In our cities today, ants clear massive amounts of junk food waste, dispatching the equivalent of 60,000 hot dogs a year from the streets of Manhattan, according to one study….

      As always with entomology, be prepared for horror stories. There’s the cockroach wasp (Ampulex dernentor), which takes control of a cockroach’s brain using precise brain surgery and induces its victim to bury itself alive, controlling its movement directly by biting into its antennae. Consider the fruit flies, which reproduce so quickly that, if unchecked, they would generate a bail of flies spanning the distance between Earth and the Sun in a single year.

      …a dragonfly can see up to 300 separate images per second, visual processing power 15 times faster than ours. If it went to the cinema, it would see a very rapid slide show rather than the moving image we perceive….

      Honey bees were among the first animals to have a close relationship with humans, with evidence of beeswax on pottery from prehistoric farming communities 9000 years ago. Given this age-old interaction, it is surprising that honey bees are not fully domesticated. Despite consuming their honey for millennia, we have not shaped them to suit us. They still sting, and there are no specialized breeds for different purposes.

      …Honey bee mating rituals are still a mystery; male bees (drones) congregate in very distinct locations 10 to 20 meters up in the air. Congregation areas can persist for decades, and queens and drones fly several kilometers to reach them, but how they are positioned and how individual bees find them are still unclear.

      Western honey bees are perfectly capable of surviving “in the wild,” without help from humans. They now live almost everywhere there is land on Earth, including across North and South America and eastern Asia, well outside their original native range of Europe, Africa, and the Middle Fast….

Deadly Cats Down Under

[These excerpts are from an article by Jonathan B. Losos in the 26 July 2019 issue of Science.]

      With their shared passion for animals, bird watchers and cat lovers should be allies. Instead, they’re often at each other’s throats. The reason is simple: We love cats—there are more cats in the United States than dogs and a loosely estimated 600 million Fells catus worldwide. The problem is that many cats are outside some or all of the time, killing birds, rodents, insects, and just about every other type of small creature. Plus, outdoor cats can spread human diseases, most notably toxoplasmosis.

      As a result, many conservationists and public health workers would like to see house cats kept indoors and stray populations greatly reduced. Unfortunately, that is easier said than done.

      The debate over the extent to which cats are a problem and, if so, what solutions to pursue has become increasingly nasty. In part, this vitriol has been the result of inflammatory statements, exaggerations, distortions, quotes taken out of context, and good old-fashioned mudslinging.

      But underlying this unpleasantness has been a lack of enough good information. An estimate that cats annually kill 1 billion to 4 billion birds in the United States—by necessity, an extrapolation from small-scale studies—has been highly controversial, but the more important question concerns which species are getting killed. Billions of pigeons might not be a matter of much concern; a lot of endangered species would be another story.

      And it matters, too, how this death toll affects bird populations. Are these the “doomed surplus” that would have died in short order because of some other cause, or is cat predation driving down bird populations and endangering species? The answer is that in the United States, the epicenter of the cat debate, we mostly just don't know.

      But there is a place where scientists do know, where research on cats and their ecological impact has been deep and broad, where cutting-edge experiments are exploring cat impacts and possible solutions. That place is Australia….

      Australia combines an unfortunate trio of circumstances that make cats a huge problem. First, the island continent is renowned for its evolutionary isolation, producing a fauna unlike that found anywhere else and thus of exceptional conservation value. Second, Australian small animals have no evolutionary experience with a predator like a cat. Cuddly cuteness notwithstanding, cats are superbly adapted killing machines; the combination of cats and prey with no evolved defenses against them—sometimes not even recognizing a cat as a threat—is a recipe for slaughter. And third, Australia has lost its larger native predators. Around the world, big predators regulate the populations of smaller ones, often by killing them. With thylacines extinct, Tasmanian devils banished from the mainland, and other large predators eliminated cats nearly have free rein.

      Synthesizing an extraordinarily large number of studies, scientists estimate that the more than 2 million feral cats in Australia annually kill 4.00 million birds and more than a half billion of both reptiles and native mammals. A wide variety of data—from historical accounts, correlations of cat abundance and prey population declines, and increased abundance of prey species both on offshore islands lacking cats and in areas where cats have been removed—all confirm that native populations are sharply and negatively affected by cats. Moreover, controlled field experiments in fenced enclosures covering many square miles—some with cats, some without—conclusively demonstrate the feline effect: Cats have an enormously negative impact on many native species.

      Painstaking research, detailed in both books, unravels more specifics: Cat impacts are often greatest during lean times, when cats switch from no-longer-abundant rabbits to other prey. In some cases, individual “catastrophic” cats hone in on a particular type of prey and can have a devastating effect….a single cat once wiped out an entire wallaby colony, for example. Overall, cats have played a major role in the extinction of 27 Australian species since European settlement and are currently threatening the existence of scores more.

      The evidence that cats are having a massive effect on Australia’s indigenous wildlife is incontrovertible, but what to do about it? Keeping pet cats indoors is one important step, but the feral cat population is a more intractable problem….

Keeping Air Pollution Policies on Track

[These excerpts are from an article by Gary W. Fuller and Anna Font in the 26 July 2019 issue of Science.]

      Around the world, thousands of instruments are measuring air pollution. The World Air Quality website provides near-real time air pollution data from stations across North America, Europe, and through the Middle East to Southeast Asia and across Australia and New Zealand. Occasionally, one of these data points leaps into the news. Beijing frequently made the headlines in the early part of this decade but, for the past 2 years, Delhi has started to dominate newspaper reports as crop burning in the surrounding area adds to the city’s considerable air pollution woes. Like many cities, Delhi now faces huge challenges to reverse its deteriorating air pollution. Most air pollution policies focus on compliance with specific pollution limits, but progress has often been slow. More effective progress may be achieved by focusing on the rate of change….

      Reframing air pollution measurement in terms of assessing trends takes us back to the purpose of the world’s first air pollution measurement network. This was set up in the United Kingdom in 1912 to track air pollution changes in a time before legal standards for ambient air pollution were conceived….

      …With an estimated 4.9 million deaths annually as a result of air pollution, the global impacts of air pollution demand urgent action. In tandem with taking action to control sources, policy makers must make better use of air pollution measurements and develop feedback loops to ensure that policies remain on track and bring health benefits for everyone.

Yellow Stingray

[Theis excerpt is from an article in the Summer 2019 issue of the American Museum of Natural History’s Rotunda.]

      …Yellow stingrays inhabit the waters throughout the Gulf of Mexico, in the Atlantic Ocean from North Carolina to Florida, and in the Bahamas and the Caribbean. Despite its common name, this species’ dorsal (top-side) patterns come in a variety of colors, from dark green or brown on light backgrounds to white, yellow, or golden spots on dark green or brown backgrounds. These dappled patterns help the stingrays lay low by blending into coral reefs and sandy sea bottoms. Meanwhile, their ventral side is typically off-white with hints of yellow, green, or brown.

      Stingrays have been likened to “flattened sharks,” and they happen to be closely related. In contrast to bony fishes, sharks and rays are both cartilaginous and belong to an ancient group called elasmobranchs. Fishes in this group have skeletons that are composed of softer structural material similar to that found in human noses, ears, and joints. Elasmobranchs also lack the air bladder that keeps many other fishes neutrally buoyant.

      And unlike most bony fishes in which females release eggs for the males to fertilize externally, yellow stingrays reproduce by copulating. During mating, male yellow stingrays have been observed grabbing the female by biting midway into her pectoral fin, then swinging beneath her, ventral side to ventral side. In this position, the male inserts one clasper into the female cloaca to deposit sperm. Females nourish the embryos in a yolk sac, as opposed to a placenta, and give birth to live young.

      Yellow stingrays are relatively small—only 30 inches across compared to larger 7-foot-wide short-tail stingrays or the massive 18-to-23-foot-wide manta ray. But like most rays, the yellow stingray has a large brain—comprising 1 to 2 percent of its body weight—and its cerebellum has three separated lobes, offering researchers a rare chance to study the connection between various behaviors and brain activity.

Fifty Years since the First Step

[These excerpts are from an article in the Summer 2019 issue of the American Museum of Natural History’s Rotunda.]

      …This summer marks the 50th anniversary of the Apollo 11 landing, which fulfilled President John F. Kennedy’s ambitious goal to send a crewed spacecraft to the Moon, When Neil Armstrong stepped onto the Moon’s surface on July 20, 1969, it was an astounding achievement. The observations and specimens from Armstrong’s and Edwin “Buzz” Aldrin’s 21-hour-and-36-minute-long stay on the Moon-which included setting up surface experiments and gathering 48.5 pounds (22 kilograms) of rock, soil, and dust samples over approximately two hours-were just the beginning….

      Once the crew returned to Earth on July 24, the collected material set off a research race and led to five additional landings that yielded more specimens and more amazing discoveries. Among them: analysis of the chemical composition of lunar rocks helped strengthen the theory that the Moon was actually a chip off the young Earth.

      Researchers now think that soon after the formation of the solar system, Earth was struck by a Mars-sized object, intimately mixing the two bodies. Some of the resulting vapor and rock later congealed into the single satellite that is our Moon today. This origin story vould explain why the Moon doesn’t have a large iron core and is mostly composed of materials found in Earth’s crust, and why the ratios of many isotopes on the Moon’s surface are identical to those found in rocks on Earth….

      Research based on materials gathered during the Apollo missions continues to this day….

      In March, NASA announced that it would open a previously unstudied cache of Moon rocks and a sedimentary core from the Apollo missions for study….

      While NASA has not returned to the surface of the Moon since 1972, it has sent missions to farther destinations in the solar system, including Mars, Saturn, and asteroids like Bennu. That has left a vacuum in lunar exploration that other nations are beginning to fill. In January, China succeeded in landing a robotic rover on the Moon’s far side, in the largest-known impact crater in our solar system, the Von Darman crater. Scientists think the far side’s rocks preserve important clues about the early solar system. The mission also carried plant seeds that successfully sprouted, and while the seedlings didn’t live long, the mission was the first ever to grow organic matter on the Moon. China's future goals include locating ice deposits on the far side, setting up a lunar base, and putting astronauts on the Moon within 10 years….

Keeping Curiosity Alive

[These excerpts are from an editorial by Ann Haley MacKenzie in the August 2019 issue of The Science Teacher.]

      …Children are curious creatures when they enter kindergarten, but by the time they enter high school, science teachers find them questioning less, not following their curiousity, and often graduating indifferent toward a life of wonder.

      But isn’t the mark of an exemplary scientist (and person) to be naturally curious throughout life? The goal for ALL science teachers is to re-instill this innate curiosity and sense of wonder in their students….

      Science teachers see more and more students coming to their classrooms with trauma-based issues. Drug-addicted parents, incarcerated family members, and turmoil at home make it difficult for students to focus on key science concepts, like natural selection, black holes, equilibrium, and plate tectonics….

Mite Fight

[These excerpts are from an op-ed article by Erik Stokstad in the 26 July 2019 issue of Science.]

      The death of his favorite queens in 2013 was the final straw for BartJan Fernhout, an amateur beekeeper in Boxmeer, the Netherlands. Fernhout’s queens, which he had purchased from a specialty breeder, produced workers with prized traits: They were calm and made plenty of honey. Then, Fernhout’s hives became infested with a parasitic mite named Varroa destructor, which has become a major contributor to the demise of bee colonies worldwide.

      Chemicals and other methods can control the parasites. But the mites are developing resistance, and the treatments sometimes don’t work—or even backfire. The chemical Fernhout used to fight his mites, for example, stopped his queens from laying eggs. That caused the workers to kill the barren queens and begin to raise new royalty, a ruthless reaction the bees evolved long ago Lto ensure the future of their hives….

      It's been slow, laborious work. Since the mite jumped from Asian honey bees (Apis cerana) to the common domesticated European honey bee (A. miffera) more than a half-century ago, researchers have discovered some bees can keep the mite in cheek through behaviors such as fastidious grooming and removing mite-infested larvae. But identifying bees able to mount these responses is tedious. A standard way to evaluate grooming, for example, is to count how many mite legs have been chewed off by vigilant bees. And the complexities of bee reproduction make it cumbersome to combine mite-resistance traits with others valued by apiarists. Although researchers and breeders have created bees that require fewer pesticides, even these colonies can be overrun by mites—and very few lines can yet survive without any treatment….

      New molecular tools promise to accelerate those efforts. A new protein-based test, for example, would allow beekeepers to simply send a laboratory a few dozen antennae, plucked from their bees, to learn whether the insects have mite-detecting powers. Other scientists are sequencing the genomes of huge numbers of bees, hoping to create a relatively cheap and easy way to identify bees that carry genes for the protective behaviors. Such a test “is almost the Holy Grail” of anti-Varroa research, Fernhout says.

      A success would help secure the future of the multibillion-dollar honey bee industry, which supplies honey and enables the large-scale pollination of high-value crops, such as almonds….

      Like other ruinous pests, Varroa started to cause trouble after it moved to a new host. One species, V. jacobsoni, is a long-standing parasite of Asian honey bees throughout their home range of southern Asia. It reproduces in the bees’ brood cells, where it feeds on the larvae, but it typically doesn’t destroy colonies. One reason is that the mite lays its eggs only on larvae that will become drones—the males that mate with queens—and hives produce only a few drones. If the mite does target the more numerous larvae of worker bees, they commit suicide (a process called social apoptosis), preventing the mite from reproducing. The natural process of starting a new colony, called swarming, also gives colonies a fresh start; when a queen and a swarm of workers abandon their old hive, they leave behind the reproducing mites as well.

      In the mid-20th century, after apiarists brought European colonies to Asia, the mite found its new host. The European bee, which beekeepers prefer for its large colonies and docile workers, generally lacked the Asian variety’s defenses. Breeders had selected against swarming behavior, for example, because keepers don’t like queens to abandon their hives. The mite quickly adapted to its new host, and it routinely infests the larvae of European worker bees. The result was a new strain of Varroa—defined as the new destructor species in 2000—which ran amok. It now afflicts European bees everywhere except Australia and a few islands.

      The role of pesticides such as neonicotinoids in honey bee die-offs is debated. But there is no question that the mites have been a major factor. V. destructor weakens both adult and larval bees by consuming their fat stores. The mite also spreads viruses, including a lethal one that deforms wings, preventing bees from flying. Parasitized colonies lose workers, make less honey, and often fail within a year if not treated.

      Modern beekeeping, which involves keeping hives in close proximity, appears to have accelerated the mite's spread. When one colony is collapsing, bees from others come to rob honey and also pick up mites and viruses….

      In theory, there is a simple solution: Don’t do anything and let natural selection eliminate bees that can’t resist the mite. It’s brutal, but it works. Populations of feral honey bees crashed after Varroa arrived, for example. Then, in a few places they began to recover, suggesting some colonies had defenses. Beekeepers who let their hives fend for themselves also saw results….

      Breeding mite-resistant bees is an increasingly appealing alternative….

      The worker taps its antennae on several cells, checking for chemical cues. Then it nibbles a hole in the mite-infested cell. Other bees, responsible for cleaning, will remove the larva from the hive, preventing the mite from reproducing. This behavior, called Varroa sensitive hygiene (VSH), is heritable and a key target for breeders….

      …they have experimentally in-fested more than 1500 colonies with mites, then selected queens from the colonies that were good at VSH. In the best hives, the bees were able to detect and remove every reproducing mite….

      And getting a resistance trait into a queen is just half the battle. Keeping it in her offspring is also a challenge. That’s because queens mate with multiple drones while flying up to 10 kilometers from their hive. The behavior provides beneficial genetic diversity to the colony but can undo a breeder’s efforts if a resistant queen mates with drones that lack mite-fighting genetics.

      Breeders can overcome this problem by artificially inseminating queens. It's a tricky technique that requires collecting semen from drones, anaesthetizing the queen with carbon dioxide, and then inseminating her under a microscope….

      Another approach is to send queens to isolated mating stations, where the only drones available for mating are ones brought there by beekeepers….

      Economics may also slow the adoption of resistant strains. The cost of treating and living with mites is low enough that many commercial beekeepers don’t see an advantage to buying improved, resistant queens. And many breeders—who can already sell every queen they produce—don’t have an incentive to invest in selecting for Varroa resistance. Researchers predict that will change if the mite continues to develop resistance to amitraz, now the pesticide of choice in many countries. “If amitraz fails,” Danka says, “the landscape changes overnight.”

      Fernhout and other breeders want to be ready for the eventuality. They are close, they believe, to creating a world in which mite-resistance genes are widespread in honey bee populations, and beekeepers can set aside their failing pesticides….

NYC to Gridlock: Drop Dead

[These excerpts are from an article by Shanti Menon in the Summer 2019 issue of EDF’s Solutions.]

      They called it the summer of hell. New York City’s underfunded transit system hit a crisis point in 2017, with commuter trains in disarray and 6 million subway riders facing 70,000 delays a month. One sultry June evening, a southbound F train stopped in a tunnel for 45 minutes. When it crawled into the station, windows fogged by body heat, desperate passengers clawed their way out like zombies. Above ground, vehicles in midtown averaged just 5 miles per hour — the slowest rate of any U.S. city, and barely faster than walking.

      The moment was ripe for a solution….we helped New York City become the first in the United States to adopt congestion pricing, a plan that imposes a fee for driving into the clogged city center. The proceeds — expected to reach at least $1 billion per year — will be invested in public transit. It’s a bold solution that addresses the city’s traffic, pollution and climate issues all at once, and it will help millions of New Yorkers breathe cleaner air. It also signals a way for other cities, such as Seattle and Los Angeles, to solve their transportation woes and meet climate goals.

      By charging vehicles to enter the most crowded parts of a city— in Manhattan, the proposed zone is south of 60th Street, with round-trip peak fees likely in the range of $12-$14 for cars — congestion pricing reduces traffic and the problems it creates, including lost time and money, climate pollution and damage to people’s lungs and quality of life.

      In other cities, the method has proved its worth. Traffic delays in Stockholm dropped 30% to 50% and the number of children hospitalized with asthma fell nearly 50%. In London, congestion pricing gives 8 million residents an extra 1,888 years of life expectancy from cleaner air, according to research from King’s College London….

      Details of New York’s plan have yet to be finalized, such as which transit improvements will get funded first….Electrifying the nation’s largest transit bus fleet could also help bring down prices for batteries nationwide.

      Seattle, Los Angeles and San Francisco are studying congestion pricing. Officials in Portland, Oregon and Philadelphia, too, are watching New York’s progress….

The New Era of Megafires

[These excerpts are from an article by Rod Griffin in the Summer 2019 issue of EDF’s Solutions.]

      Six months after the Camp Fire roared through Paradise in the Sierra foothills 90 miles north of Sacramento, the town still looks like a scene in a post-apocalyptic movie. There are signs of life — even patches of green — but the activity is mostly construction crews removing toxic debris….

      The inferno, the deadliest in California history, killed 85 people, destroyed 14,000 homes and caused $16 billion in damage. It all started with a spark from a high-voltage power line operated by PG&E, the state's largest utility. Facing multiple lawsuits, the utility declared bankruptcy in January. The Wall Street Journal called it “the first major corporate casualty of climate change….”

      Nowhere is fire risk more evident than the arid West, where tens of millions of acres are succumbing to drought and pine bark beetle infestation, providing fuel for fires. Of the 10 worst fires in California history, four have occurred since 2017 and 15 of the top 20 have been in the past two decades.

      Climate change is a clear culprit — or at least an accomplice. A 2016 study in Proceedings of the National Academy of Sciences found that climate change has doubled the number of acres burned in the West since the 1980s and that the fire season is 78 days longer than it was.

      Compounding the problem, there’s been rampant development in the wildland-urban interface, where buildings abut natural areas, posing greater fire risk to humans and making firefighting more difficult.

      In addition to the human toll, high-intensity wildfires destroy wildlife habitat, degrade water quality and pollute the air. During the Camp Fire, smoke traveled for hundreds of miles, with Northern California cities recording the worst air quality in the world….

      There are many causes for the uptick in destructive wildfires, but U.S. forest policy is one of them. For more than a century, the Forest Service has been on a mission to stamp out wildfires. The agency's chief spokesperson for the last 75 years has been Smokey Bear, whose stern message is: “Only YOU can prevent wildfires.”

      The Smokey Bear campaign, inspired by a scared bear cub found by firefighters in the Capitan Mountains in New Mexico during a wildfire, helped campers become more responsible, but it also reinforced the perception that all fire is bad. Many U.S. forests are not only adapted to burn periodically but depend on fire for rejuvenation and heath. So does wildlife.

      Today, less than 1% of wildfires are allowed to burn. As a result, forests and grasslands are overgrown. That means that when fire does come, it’s more destructive. It kills more trees, torches more homes and sends far more carbon into the atmosphere, contributing to climate change.

      In addition, unsustainable logging practices removed the largest, most fire-resistant trees from many forests, leaving smaller trees and brush that serve as ladders to move fires from forest floor to canopy. Once a fire climbs to the treetops, known as a crown fire, it can move very rapidly. Some fires burn so hot they can sterilize huge swaths of land, depleting the soil of organic matter and increasing the risk of erosion, mudslides and toxic runoff.

      Following the Camp Fire, President Trump suggested that raking the forest floor may have helped prevent the conflagration. The solution is far more complex. Forest experts say the best hope for sustaining forests will be to thin areas with dead and declining trees and use controlled burns more frequently, restoring a more resilient forest….

      The problem, of course, is bigger than California. The U.S. Forest Service estimates that between 65 and 82 million acres, from Alaska to Florida, are in need of restoration on lands within their 193-million-acre forest and grassland system. Properly managed, forests absorb carbon dioxide from the atmo-sphere and are essential for watershed quality. Forest areas produce more than half of the nation’s drinking water.

      The challenge is how to pay for all this restoration. The U.S. Congress took an important step last year when it passed the Fire Funding Fix, which will allow the Forest Service to stop diverting funds away from forest management to pay for firefighting, a practice that consumes more than half of the agency’s budget (compared to 16% in 1995)….

Banana Fungus Puts Latin America on Alert

[These excerpts are from an article by Erik Stokstad in the 19 July 2019 issue of Science.]

      In a long-feared development, an extremely damaging banana disease has apparently reached Latin America. Late last week, the Colombian Agricultural Institute (ICA) in Bogota confirmed that four plantations in northern Colombia have been quarantined because of suspected infection with Fusarium wilt tropical race 4 (TR4), a fungus that kills plants by clogging their vascular system. Already widespread in Asia, the disease can wipe out entire plantations.

      The finding has yet to be confirmed, but countries in the region are on high alert. Neighboring Ecuador is the largest banana exporter in the world; Colombia, Costa Rica, and Guatemala are big producers as well. A major outbreak of TR4 could ruin many farmers and drive up banana prices globally….

      TR4 is a variant of Panama disease, which wiped out banana plantations across Latin America in the mid-20th century. The industry recovered after it replaced the most widely cultivated banana variety at the time, Gros Michel—also known as the Big Mike—with a new one, the Cavendish, that is resistant to Panama disease and now dominates the export industry.

      TR4, which easily overcomes the defenses of the Cavendish and many other banana varieties, emerged in Indonesia in the 1960s and has spread to many other countries since then. It surfaced in Jordan in 2013, in Mozambique 2 years later, and also in India, the world’s largest banana producer. Scientists dreaded its jump to the Americas, suspecting it was only a matter of time…. /p>

      In June, staff at a large Colombian banana plantation spotted suspicious symptoms on trees and alerted ICA. After an initial polymerase chain reaction test for the fungus DNA came back positive, ICA launched its contingency plan, closing four farms and destroying all plants within 10 meters of samples that tested positive. ICA officials also established checkpoints to disinfect vehicles and boots and expanded disease surveillance in another 1100 hectares. So far, samples from the wider area have come back negative….

Making Peace with Palm Oil

[These excerpts are from an article by Dyna Rochmyaningsih in the 12 July 2019 issue of Science.]

      …Oil palm (Elaeis grrineensis) is one of the most controversial crops today, because the plantations often replace tropical rainforests rich in biodiversity depriving iconic species such as the orangutan of their habitats. Vast swaths of Indonesia and Malaysia are given over to the crop. But Agung and a growing number of other scientists say it's time to work with oil palm companies—some of them in the crosshairs of environmental activists—to make the best of a bad situation….

      Some critics call the approach naive. By accepting industry funding—and using its giant plantations as laboratories—scientists risk losing their independence, they say, and they legitimize the companies’ business by giving it a veneer of sustainability….

      But scientists working with oil palm companies say they don't feel constrained scientifically, and they welcome the money….

      Palm oil is used in a staggering number of consumer products, from fast food, chocolate spread, and cereals to toothpaste and dog chow. It is also a source of biodiesel. Some 90% of the global supply comes from Indonesia and Malaysia, where plantations cover 17 million hectares, almost half the area of Germany. Growing demand is pushing the industry into Africa and South America….

      Policies to stem the tide have not worked very well….

      Yet banning palm oil would not end biodiversity loss, according to a 2018 report by the International Union for Conservation of Nature (IUCN); it would only displace it to other parts of the globe and possibly worsen it. One hectare of tropical land can produce 4 tons of oil annually, at least four times the yield of 1 hectare of rapeseed, sunflowers, or soybeans planted in temperate regions. Unlike those crops, the oil palm is a tree that can live up to 2.5 years—enough for a diverse ecosystem to thrive in a plantation, if growers allow it….

Gut Microbes May Help Malnourished Children

[These excerpts are from an article by Elizabeth Pennisi in the 12 July 2019 issue of Science.]

      Even after starving children get enough to eat again, they often fail to grow. Their brains don’t develop properly, and they remain susceptible to diseases, even many years later. Two studies…now suggest fostering the right gut microbes may help these children recover. The work also pinpoints combinations of foods that nurture the beneficial microbes.

      Most of the experiments were in animals, but a small group of malnourished children given those foods also showed signs of improvement….

      Together, their teams reported in 2014 that the gut microbiome normally “matures” as an infant grows into a toddler. They also noticed that it remains immature in severely malnourished children, dominated by bacteria found in younger healthy children. Two years later, the researchers put mature and immature microbiomes from children into mice raised without microbes. Animals given the immature microbiomes put on less muscle, had weaker bones, and had impaired metabolisms, suggesting a mature microbiome might be needed for proper development….

Solar plus Batteries Is Now Cheaper than Fossil Power

[These excerpts are from an article by Robert F. Service in the 12 July 2019 issue of Science.]

      This month, officials in Los Angeles, California, are expected to approve a deal that would make solar power cheaper than ever while also addressing its chief flaw: It works only when the sun shines. The deal calls for a huge solar farm backed up by one of the world's largest batteries. It would provide 7% of the city's electricity beginning in 2023 at a cost of 1.997 cents per kilowatt hour (kWh) for the solar power and 1.3 cents per kWh for the battery. That's cheaper than any power generated with fossil fuel.

      …As if on cue, last week a major U.S. coal company—West Virginia-based Revelation Energy LLC—filed for bankruptcy; the second in as many weeks….

      Precipitous price declines have already driven a shift toward renewables backed by battery storage. In March, an analysis of more than 7000 global storage projects…reported that the cost of utility-scale lithium-ion batteries had fallen by 76% since 2012, and by 35% in just the past 18 months, to $187 per MWh....Another market watch firm…predicts a further halving by 2030….

      Large-scale battery storage generally relies on lithium-ion batteries—scaled-up versions of the devices that power laptops and most electric vehicles. But…batteries are only part of the energy storage an-swer, because they typically provide power for only a few hours….

      Local commitments to switch to 100% renewables are also propelling the rush toward grid-scale batteries….54 countries and eight U.S. states have required a transition to 100% renewable electricity. In 2010, California passed a mandate that the state's utilities install electricity storage equivalent to 2% of their peak electricity demand by 2024….

Balancing Science and Security

[These excerpts are from an editorial by Mary Sue Coleman in the 12 July 2019 issue of Science.]

      Federal elected officials and members of the United States intelligence community have expressed concern about the security of the nation’s scientific and technological information, articulating worries about China, Russia, and Iran. The fears include potential academic espionage, theft of intellectual property, and threats to academic integrity. As federal policy-makers respond, it is critical that they work with the scientific community to balance securing strategically important information with maintaining the free flow of fundamental scientific knowledge and international talent necessary for scientific progress. History is a guide to striking this balance.

      During the Cold War, the U.S. security community raised similar concerns about the Soviet Union….

      Building on those discussions, in 1982 the U.S. National Academy of Sciences released Scientific Communication and National Security. Citing this report, President Reagan issued National Security Decision Directive 189 (NSDD 189) in 1985. NSDD 189 states that to the maximum extent possible, the products of basic and applied research funded by the federal government should be published and widely disseminated, and that classification should be used in those limited circumstances when controlling scientific information is necessary to protect national security. NSDD 189 was reaffirmed in 2001 by Secretary of State Condoleezza Rice during the George W. Bush administration….

      The core principles underlying NSDD 189 are now threatened. Legislative proposals, such as that introduced recently in Congress by Sen. J. Hawley (R-MO), would impose new limitations on who can work on, and what information can be shared about, unclassified research projects deemed by government bureaucrats to be “sensitive”—a category that actually does not exist under current rules. If enacted, this proposal would negatively affect universities’ ability to engage in scientific research on behalf of the U.S. government.

      A more effective approach to address the current security concerns is contained in the Securing American Science and Technology Act, introduced in May by Rep. IL M. Sherrill (D-NJ) and Rep. A. Gonzalez (R-OH). This legislation, now part of a larger bill, establishes an interagency working group under the existing authority granted to the White House Office of Science and Technology Policy’s National Science and Technology Council….

      For American science to advance, basic and applied research must be openly and widely shared. At the same time, the United States must continue to benefit—as it has for decades—from the world's best and brightest scholars coming to the country to study and work. Indiscriminate restrictions on either could do irreparable harm to the U.S. scientific enterprise.

The Freedom to Teach

[These excerpts are from an article by Randi Weingarten in the Summer 2019 issue of American Education.]

      Consider what teachers have recently said about why they teach:

      “I teach because I want to change the world, one child at a time, and to show them to have passion and wonder in their learning.”

      “I teach so the next generation will question—everything. The classroom should be a place where we set children's minds free.”

      “I teach because our democracy cannot survive without citizens capable of critical analysis."

      Why I felt called to teach is best summed up by this poster I have moved from office to office since I taught in the 1990s: “Teachers inspire, encourage, empower, nurture, activate, motivate, and change the world.”

      Teaching is unlike any other profession in terms of mission, importance, complexity, impact, and fulfillment. Teachers get the importance of their work. So do parents and the public. But teachers know that some people don’t get it—whether it's the empty platitudes, or the just plain dissing. And this has taken a huge toll.

      Teachers and others who work in public schools are leaving the profession at the highest rate on record. There were 110,000 fewer teachers than were needed in the last school year, almost doubling the shortage of 2015. All 50 states started the last school year with teacher shortages.

      This is a crisis, yet policymakers have largely ignored it.

      And it’s getting worse. Enrollment in teacher preparation programs is plummeting—dropping 38 percent nationally between 2008 and 2015….

      The teacher uprisings of the last two years have laid bare the frustration over insufficient resources, deplorable facilities, and inadequate pay and benefits for educators. In what President Trump calls the “greatest economy ever,” 25 states still spend less on public education than they did a decade ago….

      In 38 states, teacher salaries are lower than before the Great Recession. Research from the Economic Policy Institute shows that teachers are paid 24 percent less than other college graduates….

      Inadequate funding for education is sometimes the result of weak economies. But more often, it is a deliberate choice—to cut funds for the public schools 90 percent of our students attend—in order to finance tax cuts for corporations and the superrich or to siphon off funds for privatization…

      Ask teachers why they leave the profession. It’s not just underfunding. Teachers are frustrated, demoralized, and really stressed. The lack of classroom autonomy and discretion supercharge that dissatisfaction….

What, Us Worry?

[These excerpts are from an article by Steve Mirsky in the July 2019 issue of Scientific American.]

      …We and the world are facing big problems, and Diamond points out that we’re never going to solve those problems without acknowledging their existence. In fact, he sets up his arguments by examining how individuals in personal crises do or do not deal with those situations successfully and then drawing analogies, when possible, to countries.

      In such a framework, a decision by a smiling Senator James Inhofe of Oklahoma in 2015 to display a snowball on the Senate floor to somehow refute the reality of climate change could be considered a symptom of a national delusional disorder.

      Of course, that disorder has really bloomed in the years since. “Not enough American citizens and politicians take our current major problems seriously,” Diamond writes, regarding the deterioration of political compromise, the increase in incivility, tainted elections (including by voter suppression) and economic inequality (Climate change is in the section on global threats.)

      …The notion of exceptionalism dates to Alexis de Tocqueville in the 19th century and originally covered the country’s democracy and personal freedoms. But in more recent times it often seems (especially if you tune for a moment to Fox News) like exceptionalism has come to signify a belief that the U.S. is simply special—and shame on you if you question that specialness.

      Nevertheless, Diamond notes, “although per-capita income is somewhat higher in the U.S. than in most European countries, life expectancy and measures of personal satisfaction are consistently higher in Western Europe. That suggests that Western European models may have much to teach us.”

      …”Skepticism about science is increasingly widespread in the U.S., and that's a very bad portent, because science is basically just the accurate description and understanding of the real world.” But as the muckraking writer Upton Sinclair put it in 1934, “It is difficult to get a man to understand something, when his salary depends upon his not understanding it.” Especially if that man is a U.S. senator.

Broken Promises

[This excerpt is from an article by Rowan Moore Gerety in the July 2019 issue of Scientific American.]

      Madagascar broke free of the land that makes up Africa and India nearly 100 million years ago. Across the eons, evolution in isolation has given the island unparalleled ecological richness: Four out of five plants and animals there are found nowhere else, the sweeping cast of characters in a wide array of highly specialized symbiotic niches. The country’s 83 species of screw pine alone serve as breeding grounds for dozens of different reptiles and amphibians. But the ballet between this particular tree and frog is now confined to a tiny collection of forest fragments….

      Rio Tinto came to Madagascar in the 1980s, looking for ilmenite, a mineral used to make titanium dioxide, which pro vides the white pigment found in products ranging from pain and plastics to toothpaste. Test pits hit pay dirt near Tolagnaro (Fort Dauphin), at the southeastern tip of the island. The ilmenite deposits that interest the company lie underneath the rem nants of dense evergreen forests that once grew on sand dune along most of Madagascar’s eastern coast, forming a contin ous band covering perhaps 465,000 hectares. Since human colonization of the island some 2,000 years ago, these littoral forests, as they are known, have dwindled to at most 10 percent o their original expanse. As such, Rio Tinto’s concession weav through one of the most threatened ecosystems on the planet.

      …When ilmenite prices slumped during the Great Recession, Rio Tinto’s priorities shifted, and by 2016, the company reneged on its grand conservation promise. Instead it adopted the vague goal of avoiding making things too much worse. Today mining near Mandena is poised to extinguish this biodiversity hotspot. For the people who live there and dozens of endemic species such as the ring-wearing tree frog, destiny now turns on the outcome of this long-running experiment, a test case for industry’s role in conservation and the role conservationists can play in the mining industry….

      Rio Tinto discovered ilmenite near Tolagnaro in 1986. At the time, the forests in the region were already heavily fragmented and degraded by human activity. But the company’s prospecting soon brought new roads to the area and an influx of people looking for work, hastening the deforestation underway for charcoal production and new farmland to supply the growing city.

      Rio Tinto determined that the region around Toiagnaro contained some 70 million metric tons of ilmenite—enough to supply about 10 percent of the global market for a decade or more—and began to make a plan for extracting it. The company set its sights on three mineral-rich areas along the coast encompassing a total of approximately 6,000 hectares. Mining would start at the 2,000-hectare site in Mandena and eventually expand north to Sainte Luce and to Petriky farther south. The extraction would continue for the life of the mine—about 60 years from the date of first production, according to the company’s projections. Rio Tinto estimated that in the end the project would result in the loss of 1,665 hectares, or 3.5 percent, of Madagascar’s remaining littoral forest….

      Despite Rio Tinto's support for ecological research in Madagascar, by the early 2000s the company’s global track record had earned it a reputation as an unscrupulous actor in a heavily polluting industry. In Papua New Guinea, where Rio Tinto had developed a giant copper mine in the 1980s, protests brought on by the company’s disparate treatment of white foreigners and local workers forced the mine.s closure and helped to spark a civil war. Thirty years later Rio Tinto is gone, but pollution from the shuttered Panguna mine will still cost an estimated $1 billion to clean up….

“Emotional AI” Sounds Appealing

[This excerpt is from an article by Zeynep Tufekci in the July 2019 issue of Scientific American.]

      …And right out of the gate, advertisers and marketers have jumped on this technology. For example, Coca-Cola has hired a company called Affectiva, which markets emotion-recognition software, to fine-tune ads. As usual, money is driving this not so noble quest: research shows that ads that trigger strong emotional reactions are better at getting us to spend than ads using rational or informational approaches. Emotional recognition can also be used in principle for pricing and marketing in ways that just couldn't be done before. As you stand before that vending machine, how thirsty do you look? Prices may change accordingly. Hungry? Hot dogs may get more expensive.

      This technology will almost certainly be used along with facial-recognition algorithms. As you step into a store, cameras could capture your countenance, identify you and pull up your data. The salesperson might get discreet tips on how to get you to purchase that sweater—Appeal to your ego? Capitalize on your insecurities? Offer accessories and matching pieces?—while coupons customized to lure you start flashing on your phone. Do the databases know you have a job interview tomorrow? Okay, here’s a coupon for that blazer or tie. Are you flagged as someone who shops but doesn't buy or has limited finances? You may be ignored or even tailed suspiciously.

      One potential, and almost inevitable, use of emotion-recognition software will be to identify people who have “undesirable” behaviors. As usual, the first applications will likely be about security. At a recent Taylor Swift concert, for example, facial recognition was reportedly used to try to spot potential troublemakers. The software is already being deployed in U.S. airports, and it’s a matter of time before it may start doing more than identifying known security risks or stalkers. Who’s too nervous? Who's acting guilty?

      In more authoritarian countries, this software may turn to identifying malcontents. In China, an app pushed by the Communist party has more than 100 million registered users—the most downloaded app in Apple’s digital store in the nation. In a country already known for digital surveillance and a “social credit system” that rewards and punishes based on behavior the party favors or frowns on, it’s not surprising that so many people have downloaded an app that the New York Times describes as “devoted to promoting President Xi Jinping.” Soon people in China may not even be able to roll their eyes while they use the app: the phone's camera could gauge their vivacity and happiness as they read Xi’s latest quotes, then deduct points for those who appear less than fully enthusiastic.

      It’s not just China: the European Union is piloting a sort of “virtual agent” at its borders that will use what some have called an “AI lie detector.” Similar systems are being deployed by the U.S. government. How long before companies start measuring whether customer service agents are smiling enough? It may seem like a giant leap from selling soda to enforcing emotional compliance, and there can certainly be some positive uses for these technologies. But the people pushing them tend to accentuate the positive and downplay the potential downside. Remember Facebook’s feel-good early days…?

How Matter Becomes Mind

[These excerpts are from an article by Max Bertolero and Danielle S. Bassett in the July 2019 issue of Scientific American.]

      Networks pervade our lives. Every day we use intricale networks of roads, railways, maritime routes and skyways traversed by commercial flights. They exist even beyond our immediate experience. Think of the World Wide Web, the power grid and the universe, of which the Milky Way is an infinitesimal node in a seemingly boundless network of galaxies. Few such systems of interacting connections, however, match the complexity of the one underneath our skull.

      Neuroscience has gained a higher profile in recent years, as many people have grown familiar with splashily colored images that show brain regions “lighting up” during a mental task. There is, for instance, the temporal lobe, the area by your ear, which is involved with memory, and the occipital lobe at the back of your head, which dedicates itself to vision.

      What has been missing from this account of human brain function is how all these distinct regions interact to give rise to who we are….In the most fundamental sense, what the brain is—and thus who we are as conscious beings—is, in fact, defined by a sprawling network of 100 billion neurons with at least 100 trillion con-necting points, or synapses.

      Network neuroscience seeks to capture this complexity….

      To undersand how networks underlie our cognitive capabilities, first consider the analogy of an orchestra playing a symphony. Until recently, neuroscientists have largely studied the functioning of individual brain regions in isolation, the neural equivalent of separate brass, percussion, strings and woodwind sections. In the brain, this stratification represents an approach that dates back to Plato—quite simply, it entails carving nature at the joints and then studying the individual components that remain.

      Just as it is useful to understand how the amygdala helps to process emotions, it is similarly vital to grasp how a violin produces high-pitched sounds. Still, even a complete list of brain regions and their functions—vision, motor, emotion, and so on—does not tell us how the brain really works. Nor does an inventory of instruments provide a recipe for Beethoven’s Eroica symphony.

      …Put another way, just as a collection of instruments is not music, an assemblage of wires does not represent brain function….

      At any moment, though, some areas within the three-pound organ are more active than others. We have all heard the saying that people use a small fraction of their brain capacity. In fact, the entire brain is active at any point in time, but a given task modulates the activity of only a portion of the brain from its baseline level of activity.

      That arrangement does not mean that you fulfill only half of your cognitive potential. In fact, if your entire brain were strongly active at the same time, it would be as if all the orchestra members were playing as loudly as possible—and that scenario would create chaos, not enable communication. The deafening sound would not convey the emotional overtones present in a great musical piece. It is the pitch, rhythms, tempo and strategic pauses that communicate information, both during a symphony and inside your head.

      …Imagine a scenario in which every musician in an orchestra had to change the notes played every time another musician changed his or her notes. The orchestra would spiral out of control and would certainly not produce aesthetically pleasing sounds. Processing in the brain is similar—each module must be able to function mostly independently. Philosophers as early as Plato and as recent as Jerry Fodor have noted this necessity, and our research confirms it.

      Even though brain modules are largely independent, a symphony requires that families of instruments be played in unison….Watching a movie with only a brain module for vision—without access to the one for emotions—would detract greatly from the experience.

      For that reason, to complete many cognitive tasks, modules must often work together….

      Although our brains have certain basic network components—modules interconnected by hubs—each of us shows slight variations in the way our neural circuits are wired. Researchers have recently devoted intense scrutiny to this diversity….

      …brain-connectivity patterns establish a “fingerprint” that distinguishes each individual. People with strong functional connections among certain regions have an extensive vocabulary and exhibit higher fluid intelligence—helpful for solving novel problems—and are able to delay gratification. They tend to have more education and life satisfaction and better memory and attention. Others with weaker functional connections among those same brain areas have lower fluid intelligence, histories of substance abuse, poor sleep and a decreased capacity for concentration.

      …If your brain network has strong hubs with many connections across modules, it tends to have modules that are clearly segregated from one another, and you will perform better on a range of tasks, from short-term memory to mathematics, language or social cognition. Put simply, your thoughts, feelings, quirks, flaws and mental strengths are all encoded by the specific organization of the brain as a unified, integrated network. In sum, it is the music your brain plays that makes you you….

      Transformations in both structural and functional connectivity are important during adolescent brain development, when the finishing touches of the brain’s wiring diagram are being refined. This period is of critical importance because the first signs of mental disorders often appear in adolescence or early adulthood.

      One area our research relates to is understanding how brain networks develop through childhood and adolescence and into adulthood. These processes are driven by underlying physiological changes, but they are also influenced by learning, exposure to new ideas and skills, an individual's socioeconomic status and other experiences.

      …We have also found that the extent to which modules segregate from one another is more rapid in children who have a higher socioeconomic status, highlighting the key impact of their environment.

      …The areas identified as hubs are also the locations in the human brain that have expanded the most during evolution, making them up to 30 times the size they are in macaques. Larger brain hubs most likely permit greater integration of processing across modules and so sup-port more complex computations….

      This simulation demonstrates that one potential solution to evolving a brain capable of exchanging information among modules requires hubs with strong connections. Notably, real networks—brains, airports, power grids—also have durable, tightly interconnected hubs, exactly as predicted by evolutionary experiments. That observation does not mean evolution necessarily occurred in the same way as the simulation, but it shows La possible means by which one of nature's tricks might operate….

The Grand Story of Carbon

[This excerpt is from a book report by Nicola Pohl in the 5 July 2019 issue of Science.]

      Although organic chemistry is often described as the science of carbon, Robert Hazen's latest book, Symphony in C, makes clear that this vital element cannot be contained by such a disciplinary boundary.

      Despite its abundance and importance, the location and cycling of carbon on Earth are not yet well understood. Ever-increasing atmospheric concentrations of its dioxide form lend urgency to a more accurate accounting of this element. However, it is Hazen’s enthusiasm, the string of shareable facts presented, and the introduction of so many interesting scientists that make this book such a fascinating read.

      …In the first section, “Earth”—the most well-developed of the book—Hazen discusses carbon-based minerals, offering a wonderful account of how mineralogy has gradually turned from a purely observational science to one that can predict missing carbon-containing minerals….

      The extreme pressures and temperatures hundreds of miles below Earth’s surface form denser crystalline minerals, but almost none of the ~400 currently known carbon minerals are in high-pressure phases. Hazen has been fascinated by experimental efforts to mimic these extreme pressures since he was a graduate student, and he details the methods being used to reach 80,000-fold or greater atmospheres of pressure. Such high pressures do not lead only to simple structures, we learn. Additional surprises await when Hazen ex-plores deeper toward Earth’s core.

      The second section, “Air,” starts with a very brief history of Earth before discussing carbon in the air—primarily carbon dioxide—and its cycling through the atmosphere. Hazen finishes this section with a wonderful discussion of the biases that humans, including scientists, have and the challenges they bring to forming a more integrated picture of the world….

      “Fire” is devoted to the many ways we manipulate carbon, using it to create plastic materials, for example, as well as other products of modern organic chemistry….

      The final pages of the book end with a very personal look at what Hazen calls the “human carbon cycle”—exploring how we consume and expel carbon—and examines our responsibility to our carbon-based home….

Quest for Fire

[These excerpts are from an article by Robert F. Service in the 5 July 2019 issue of Science.]

      …His elixir is gasoline. Nearly everyone in the developed world is hopelessly addicted to it. Collectively, we use nearly 3 trillion liters every year….

      But before the demo, the machine sprang a leak. Although it wasn’t operating at the pitch fest, McGinnis’s optimism was. He promised audience members that the repaired device would extract carbon dioxide (CO2) from the air, add it to water, and use a catalyst to rearrange the chemical bonds to make hydrocarbons. The result: fossil fuel without the fossils. “It can sound like magic, but it’s really just chemistry,” McGinnis told the audience.

      Synthesizing gasoline, instead of refining it from oil, isn’t a new idea. German chemists hi the 1920s discovered they could turn coal into carbon monoxide (CO) and hydrogen—a combination known as synthesis gas. Catalysts, along with heat and pressure, could then transform synthesis gas into gasoline and other liquid hydrocarbons.

      But McGinnis’s setup requires no heat, pressure, or coal. It uses only air, water, and electricity, which can come from the sun or wind. And with those renewable resources becoming ever cheaper, he's betting he can deliver gasoline more economically—and far more cleanly—than companies that must find oil, drill for it, ship it, and refine it.

      Several other startups and academic labs are pursuing the same dream….

      Yet many of those efforts have stumbled over the expensive, energy-intensive steps needed to separate the hydrocarbons from the water they are produced in. Prometheus relies instead on a proprietary carbon nanotube membrane sieve that it says readily parts the hydrocarbons from water….

      Once the machine is working efficiently, electricity will make up about one-third of its operating costs. Renewable electricity prices around the globe are falling, however, and they already sink near zero at certain times of the day in places where the sun blazes or the wind howls. Prometheus, McGinnis says, could easily ramp its electricity demands up and down to take advantage of the lowest rates, and the machines could be sited wherever renewable power is cheapest….

      Even if all goes according to plan, McGinnis will face a long mad to compete with the likes of ExxonMobil. He'll have to prove he can build a fuelmaker cheaply enough to make its gasoline aBordable. That could be tough if turning it on makes sense only when renewable electricity prices bottom out. The fuehnaker also works only with a source of clean water. And before he can market his invention, he'll need to prove that his fuels can directly substitute for fossil-derived versions….

FDA Enforcement Actons Plummet under Trump

[These excerpts are from an article by Charles Piller in the 5 July 2019 issue of Science.]

      From monitoring clinical trials and approving medicines and vaccines, to ensuring the safety of blood transfusions, medical devices, groceries, and more, the U.S. Food and Drug Administration (FDA) is one of the nation's most vital watchdogs. By several measures, however, FDA’s compliance and enforcement actions have plummeted since President Donald Trump took office….

      The agency’s “warning letters”—a key tool for keeping dangerous or ineffective drugs and devices and tainted foods off the market—have fallen by one-third, for example. Such letters typically demand swift corrections to protect public health and safety….

      Warnings from the FDA Center for Devices and Radiological Health, which helps ensure the safety and quality of medical devices, and from some of the agency's district offices—including Philadelphia, Florida, and New York—have dropped even more steeply, by more than two-thirds. Two district offices have not issued a warning in more than 2 years. The numbers don’t just reflect a new administration's slow start. FDA sent significantly fewer warning letters in the second year of Trump’s presidency than in his first.

      FDA watchers say they can’t pinpoint what’s driving the decline, but they are alarmed….

      Several other FDA actions under Trump show similar dedines when measured against the end of the Obama administration. FDA inspection reports labeled “official action indicated”—typically a trigger for warning letters or similar actions—have fallen by about half under Trump and are continuing to trend downward….

Contrails Threaten Climate

[This news brief is in the 5 July 2019 issue of Science.]

      Carbon emissions from aviation are a well-known contributor to climate warming. But another byproduct of planes—the white contrails they paint across the sky—has an even bigger effect. Contrails form when water vapor in a plane's exhaust freezes, and unlike low-level clouds that reflect sunlight to cool the atmosphere, they trap heat radiated from Earth's surface, warming it. A new model described last week in Atmospheric Chemistry and Physics is the first to classify contrail clouds separately from natural ones. Researchers predicted a threefold increase in contrail warming effects by 2050. They also estimated that a 50% reduction in airplane soot, which promotes the formation of contrails, would lead to a 15% decrease in those effects. But such reductions are unlikely; global air traffic is surging, and most pollution-reduction plans in the industry fail to consider climate impact beyond carbon dioxide emissions.

Chinese Scientists and Security

[These excerpts are from an editorial by Elias Zerhouri in the 5 July 2019 issue of Science.]

      …We should remember that for years, scientific exchanges and collaborations with China were encouraged by U.S. policy-makers, including implicit support of China’s Thousand Talents Program. Chinese-born as well as American-born federally funded scientists were publicly offered various positions in China over the years without opposition by relevant institutions. The “rules,” now presented and enforced as severe violations of U.S. ethics and intellectual property regulations, were not rigorously implemented by officials at many U.S. institutions. The consternation, sense of targeted discrimination, and fear in the Chinese-American scientific community are thus understandable.

      U.S. science and technology are a cornerstone of competitiveness and preeminence in the world, and the security and protection of this vital enterprise are of paramount importance. But unlike most other countries, the United States relies heavily on attracting the best and brightest in the world to its ecosystem of innovation because of an insufficient number of graduates in science, technology, engineering, and mathematics fields relative to the size and technological intensity of its economy. Would it be in the national interest to risk losing all or some of the extraordinarily productive Chinese-American scientific diaspora trained and supported for years in the United States?

      …most Chinese-born scientists prefer to stay in the United States for personal and family preferences. One can imagine the glee of Chinese officials at the prospect of thousands of Chinese-American scientists, whom they were unable to recruit until now, relocating back to China. So, what should be done?

      …No members of any community should be targeted because of their origins, rather than for what they may have intentionally and demonstrably done to harm U.S. science and technology. The United States should not risk losing critical intellectual assets such as productive foreign-born scientists and engineers to global competitors to serve short-term security concerns at the expense of long-term national interests.

Genomic Surveillance for Malaria

[These excerpts are from an article by Ify Aniebo in the July 2019 issue of Scientific American.]

      In 2018 the World Health Organization proposed a “10+1” initiative for malaria control and elimination that targets 10 African countries plus India, which together host 70 percent of global cases. Although this approach is promising, it is missing an important component: genomic surveillance. Drug resistance threatens all of the progress made so far against malaria, but genomic surveillance can detect resistance years before the first warning signs appear in clinics. It can answer critical questions about how resistance emerges and spreads and can help control the balance of interventions, preserve the useful life of already existing drugs and ensure effective treatment.

      …This genomic information can help malaria-control programs use quality data sets for regular monitoring of drug resistance, provide evidence-based decision-making around malaria policy and assist in managing the spread of resistance.

      The countries most affected by malaria all had a first-line drug that ended up becoming resistant. In African countries, toward the end of the 20th century, chloroquine was the drug of choice, but malaria parasites grew resistant to it. That drug was theh replaced with a combination of pyrirnethamine and sulfadoxine in the early 2000s, and resistance again occurred. Now the parasites are becoming resistant to the current first-line artemisinin-based combination therapies (ACTs)….

      …The more drugs we use to treat malaria parasites, the more resistant they become as a result of selective pressure, which creates the preconditions for resistance. Because we know this biological response from the parasites is inevitable, we should put in place measures to track down these changes when they arise: doing so would help us prevent the spread of the disease, investigate emergence of resistance and subsequently preserve the efficacy of the current first-line antimalarial treatment.

      With advances in genomic technology, scientists have been able to analyze malaria parasites from the patients carrying them and the mosquitoes transmitting them. Such analysis has become a source of relevant information for both drug and insecticide resistance. Research shows that genomic surveillance has helped us understand how different mosquito species arise and transmit malaria to humans, which in turn has led to a better targeting of interventions as vectorial capacity becomes better understood.

      Such surveillance has enabled greater knowledge of changing transmission intensity and parasite gene flow, including drug-resistant genes, and has aided in quantifying the risks of importing malaria from a country that is burdened with the disease. But work using genomic surveillance as a tool has mostly transpired within the realm of research, with only a few examples of its application in the field where malaria burden remains high.

      Genomic surveillance has been used in countries that have eliminated malaria to prevent its resurgence and in countries that are in a malaria-elimination phase. It should not be any different for the. African countries that have the highest malaria burden. Lessons learned from poliomyelitis show that genomic surveillance played a huge role in controlling the infection.

Lucky Charms

[These excerpts are from an article by Clara Moskowitz in the July 2019 issue of Scientific American.]

      We could have been living in an antimatter universe, but we are not. Antimatter is matter’s upside-down twin—every matter particle has a matching antimatter version with the opposite charge. Physicists think the cosmos started out with just as much antimatter as matter, but most of the former got wiped out. Now they may be one step closer to knowing why.

      Researchers…have discovered antimatter and matter versions of “charm” quarks—one of six types, or flavors, of a class of elementary matter particles—acting differently from one another….

      Matter and antimatter annihilate each other on contact, and researchers believe such collisions destroyed almost all of the antimatter (and a large chunk of the matter) that initially existed in the cosmos. But they do not understand why a relatively small excess of matter survived to become the stars and planets and the rest of the cosmos. Consequently, physicists have been looking for a kind of matter that behaves so differently from its antimatter version that it would have had time to generate this excess in the early universe.

      The newly discovered mismatch in decay rates between charm quarks and antiquaries turns out to be too small to account for the universe’s excess of matter….

      Physicists previously found similar variations in two other quark flavors, but those were also too tiny to account for our matter-dominated universe. Scientists are holding out hope of finding much larger matter-antimatter differences elsewhere, such as in ghostly particles called neutrinos or reactions involving the Higgs boson—the particle that gives others mass….

Science Research Pays Off

[These excerpts are from an article by Peter Dizikes in the July/August 2019 issue of MIT News.]

      The Human Genome Project helped scientists make the first complete map of human genes. But the $3 billion,15-year project was also a remarkably successful investment: in 2012, human genome sequencing accounted for an estimated 280,000 jobs, $19 billion in personal income, $3.9 billion in federal taxes, and $2.1 billion in state and local taxes, all for just $2 per year per US resident….

      It’s hardly the only science-based payoff out there. Every $10 million in public science funding granted to the National Institutes of Health produces 2.7 patents and an additional $30 million in value for the private-sector firms that own them; meanwhile, each dollar in publicly funded military R&D leads to another $2.50 to $5.90 in private-sector investment.

      Once upon a time, the US steadily increased public investment in science. In 1938, the country allocated under one-tenth of 1% of its national income to science research. By 1944, the war had boosted that to 0.5%, and by 1964, 2% of GDP was invested in science research. But today, that figure has dropped to 0.7% of GDP, and overall growth rates have lagged compared with the first postwar decades.

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